AT3G60180 : -
Query Information
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AGICode AT3G60180
Description P-loop containing nucleoside triphosphate hydrolases superfamily protein
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT3G60180 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 1 0.31 -0.3
2 AT5G63800 Glycosyl hydrolase family 35 protein beta-galactosidase 6,
MUCILAGE-MODIFIED 2		 0.81 0.31 -0.32
3 AT3G13570 SC35-like splicing factor 30A SC35-like splicing factor 30A,
SC35-like splicing factor 30A		 -0.78 0.33 -0.3
4 AT4G38460 geranylgeranyl reductase geranylgeranyl reductase 0.76 0.32 -0.31
5 AT4G17940 Tetratricopeptide repeat (TPR)-like superfamily protein 0.76 0.32 -0.34
6 AT1G31820 Amino acid permease family protein 0.76 0.34 -0.3
7 AT4G32520 serine hydroxymethyltransferase 3 SERINE HYDROXYMETHYLTRANSFERASE 3,
serine hydroxymethyltransferase 3		 -0.75 0.3 -0.31
8 AT1G02090 Proteasome component (PCI) domain protein ARABIDOPSIS THALIANA COP9
SIGNALOSOME SUBUNIT 7,
CONSTITUTIVE PHOTOMORPHOGENIC 15,
COP9 SIGNALOSOME SUBUNIT 7, FUSCA
5		 -0.75 0.32 -0.31
9 AT3G01520 Adenine nucleotide alpha hydrolases-like superfamily
protein		 0.75 0.32 -0.32
10 AT5G49650 xylulose kinase-2 xylulose kinase-2, XYLULOSE KINASE
2		 0.74 0.31 -0.3
11 AT1G13560 aminoalcoholphosphotransferase 1 aminoalcoholphosphotransferase 1,
ATAAPT1		 -0.74 0.33 -0.33
12 AT5G22460 alpha/beta-Hydrolases superfamily protein 0.74 0.32 -0.3
13 AT5G65760 Serine carboxypeptidase S28 family protein 0.73 0.33 -0.32
14 AT3G61540 alpha/beta-Hydrolases superfamily protein 0.73 0.31 -0.29
15 AT5G36910 thionin 2.2 thionin 2.2 -0.72 0.32 -0.29
16 AT3G13672 TRAF-like superfamily protein 0.72 0.35 -0.31
17 AT2G26830 Protein kinase superfamily protein embryo defective 1187 -0.72 0.32 -0.32
18 AT5G12470 Protein of unknown function (DUF3411) -0.71 0.32 -0.31
19 AT5G03230 Protein of unknown function, DUF584 0.71 0.34 -0.29
20 AT1G48320 Thioesterase superfamily protein 0.71 0.31 -0.31
21 AT5G27470 seryl-tRNA synthetase / serine--tRNA ligase -0.71 0.32 -0.29
22 AT2G22660 Protein of unknown function (duplicated DUF1399) 0.71 0.29 -0.32
23 AT5G26360 TCP-1/cpn60 chaperonin family protein -0.7 0.33 -0.31
24 AT4G35310 calmodulin-domain protein kinase 5 ATCPK5, calmodulin-domain protein
kinase 5		 -0.7 0.32 -0.32
25 AT1G03360 ribosomal RNA processing 4 ribosomal RNA processing 4,
ribosomal RNA processing 4		 -0.7 0.32 -0.34
26 AT1G20220 Alba DNA/RNA-binding protein -0.7 0.31 -0.32
27 AT4G29890 choline monooxygenase, putative (CMO-like) 0.7 0.34 -0.32
28 AT5G64280 dicarboxylate transporter 2.2 dicarboxylate transporter 2.2 0.7 0.31 -0.31
29 AT1G66530 Arginyl-tRNA synthetase, class Ic -0.7 0.29 -0.32
30 AT5G66540 FUNCTIONS IN: molecular_function unknown; INVOLVED IN: rRNA
processing; LOCATED IN: cytosol, nucleolus, nucleus;
EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12
growth stages; CONTAINS InterPro DOMAIN/s: U3 small
nucleolar ribonucleoprotein complex, subunit Mpp10p
(InterPro:IPR012173), Mpp10 protein (InterPro:IPR007151);
Has 30201 Blast hits to 17322 proteins in 780 species:
Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi -
3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996
(source: NCBI BLink).		 -0.69 0.3 -0.31
31 AT2G14080 Disease resistance protein (TIR-NBS-LRR class) family 0.69 0.3 -0.3
32 AT1G62810 Copper amine oxidase family protein 0.69 0.32 -0.3
33 AT2G18220 Noc2p family -0.69 0.33 -0.3
34 AT3G03150 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
mitochondrion; EXPRESSED IN: 22 plant structures; EXPRESSED
DURING: 13 growth stages; BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT5G17165.1); Has 39 Blast
hits to 39 proteins in 11 species: Archae - 0; Bacteria -
0; Metazoa - 0; Fungi - 0; Plants - 39; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 0.69 0.32 -0.32
35 AT3G03470 cytochrome P450, family 87, subfamily A, polypeptide 9 cytochrome P450, family 87,
subfamily A, polypeptide 9		 0.69 0.32 -0.29
36 AT1G77030 hydrolases, acting on acid anhydrides, in
phosphorus-containing anhydrides;ATP-dependent
helicases;nucleic acid binding;ATP binding;RNA
binding;helicases		 -0.69 0.33 -0.31
37 AT2G27100 C2H2 zinc-finger protein SERRATE (SE) SERRATE -0.69 0.32 -0.31
38 AT1G52930 Ribosomal RNA processing Brix domain protein -0.68 0.29 -0.33
39 AT4G18975 Pentatricopeptide repeat (PPR) superfamily protein 0.68 0.31 -0.31
40 AT4G31790 Tetrapyrrole (Corrin/Porphyrin) Methylases -0.68 0.3 -0.31
41 AT3G15460 Ribosomal RNA processing Brix domain protein -0.68 0.31 -0.29
42 AT2G34040 Apoptosis inhibitory protein 5 (API5) -0.68 0.31 -0.3
43 AT5G11720 Glycosyl hydrolases family 31 protein 0.68 0.32 -0.31
44 AT2G38730 Cyclophilin-like peptidyl-prolyl cis-trans isomerase family
protein		 -0.68 0.31 -0.31
45 AT3G07350 Protein of unknown function (DUF506) 0.68 0.33 -0.32
46 AT3G46040 ribosomal protein S15A D ribosomal protein S15A D -0.68 0.31 -0.33
47 AT4G29820 homolog of CFIM-25 ARABIDOPSIS THALIANA HOMOLOG OF
CFIM-25, homolog of CFIM-25		 0.67 0.32 -0.33
48 AT1G32440 plastidial pyruvate kinase 3 plastidial pyruvate kinase 3 -0.67 0.3 -0.33
49 AT1G54740 Protein of unknown function (DUF3049) 0.67 0.31 -0.31
50 AT3G60690 SAUR-like auxin-responsive protein family 0.67 0.31 -0.32
51 AT1G25490 ARM repeat superfamily protein ATB BETA BETA, ENHANCED ETHYLENE
RESPONSE 1, ROOTS CURL IN NPA,
REGA		 -0.67 0.31 -0.33
52 AT4G08290 nodulin MtN21 /EamA-like transporter family protein 0.67 0.32 -0.28
53 AT5G11630 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED
DURING: 13 growth stages; BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT4G17310.1); Has 90 Blast
hits to 90 proteins in 10 species: Archae - 0; Bacteria -
0; Metazoa - 0; Fungi - 0; Plants - 90; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.67 0.31 -0.31
54 AT3G12750 zinc transporter 1 precursor zinc transporter 1 precursor 0.67 0.3 -0.31
55 AT3G60360 embryo sac development arrest 14 EMBRYO SAC DEVELOPMENT ARREST 14,
U3 SMALL NUCLEOLAR RNA-ASSOCIATED
PROTEIN 11		 -0.67 0.33 -0.29
56 AT5G19860 Protein of unknown function, DUF538 0.67 0.3 -0.32
57 AT5G59960 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED
DURING: 15 growth stages; Has 30201 Blast hits to 17322
proteins in 780 species: Archae - 12; Bacteria - 1396;
Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0;
Other Eukaryotes - 2996 (source: NCBI BLink).		 0.67 0.32 -0.3
58 AT3G07910 FUNCTIONS IN: molecular_function unknown; INVOLVED IN:
biological_process unknown; LOCATED IN: endomembrane
system; EXPRESSED IN: 24 plant structures; EXPRESSED
DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s:
Reactive oxygen species modulator 1 (InterPro:IPR018450);
Has 192 Blast hits to 192 proteins in 80 species: Archae -
0; Bacteria - 0; Metazoa - 139; Fungi - 6; Plants - 39;
Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).		 -0.66 0.33 -0.32
59 AT1G21920 Histone H3 K4-specific methyltransferase SET7/9 family
protein		 0.66 0.31 -0.34
60 AT4G28020 unknown protein; CONTAINS InterPro DOMAIN/s:
Uncharacterised protein family UPF0066
(InterPro:IPR001378); Has 30201 Blast hits to 17322
proteins in 780 species: Archae - 12; Bacteria - 1396;
Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0;
Other Eukaryotes - 2996 (source: NCBI BLink).		 -0.66 0.33 -0.32
61 AT2G35940 BEL1-like homeodomain 1 BEL1-like homeodomain 1, embryo
sac development arrest 29		 0.66 0.32 -0.32
62 AT1G08580 unknown protein; Has 39 Blast hits to 39 proteins in 15
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 35; Viruses - 0; Other Eukaryotes - 4 (source:
NCBI BLink).		 -0.66 0.3 -0.3
63 AT3G04470 Ankyrin repeat family protein -0.66 0.32 -0.31
64 AT2G35680 Phosphotyrosine protein phosphatases superfamily protein 0.66 0.29 -0.34
65 AT5G18820 TCP-1/cpn60 chaperonin family protein chaperonin-60alpha2, embryo
defective 3007		 -0.66 0.32 -0.33
66 AT3G53500 RNA-binding (RRM/RBD/RNP motifs) family protein with
retrovirus zinc finger-like domain		 arginine/serine-rich zinc
knuckle-containing protein 32,
arginine/serine-rich zinc
knuckle-containing protein 32,
arginine/serine-rich zinc
knuckle-containing protein 32		 -0.66 0.32 -0.32
67 AT5G20700 Protein of unknown function (DUF581) 0.65 0.32 -0.32
68 AT3G49990 unknown protein; Has 1524 Blast hits to 1298 proteins in
225 species: Archae - 9; Bacteria - 84; Metazoa - 474;
Fungi - 184; Plants - 98; Viruses - 17; Other Eukaryotes -
658 (source: NCBI BLink).		 -0.65 0.29 -0.31
69 AT1G73920 alpha/beta-Hydrolases superfamily protein 0.65 0.31 -0.31
70 AT1G79150 binding -0.65 0.33 -0.32
71 AT1G28580 GDSL-like Lipase/Acylhydrolase superfamily protein 0.65 0.31 -0.32
72 AT3G55620 Translation initiation factor IF6 eukaryotic initiation facor 6A,
embryo defective 1624		 -0.65 0.33 -0.31
73 AT5G49460 ATP citrate lyase subunit B 2 ATP citrate lyase subunit B 2 -0.65 0.31 -0.31
74 AT5G38780 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 0.65 0.31 -0.34
75 AT2G40420 Transmembrane amino acid transporter family protein 0.64 0.28 -0.29
76 AT5G24316 proline-rich family protein 0.64 0.32 -0.34
77 AT1G66740 ASF1 like histone chaperone ANTI- SILENCING FUNCTION 1A,
AtSP7, SGA2, SP7		 -0.64 0.3 -0.3
78 AT3G24530 AAA-type ATPase family protein / ankyrin repeat family
protein		 -0.64 0.32 -0.3
79 AT3G59940 Galactose oxidase/kelch repeat superfamily protein 0.64 0.31 -0.3
80 AT2G35060 K+ uptake permease 11 K+ uptake permease 11 0.64 0.31 -0.32
81 AT3G05990 Leucine-rich repeat (LRR) family protein -0.64 0.31 -0.29
82 AT3G14100 RNA-binding (RRM/RBD/RNP motifs) family protein 0.64 0.3 -0.29
83 AT1G31020 thioredoxin O2 thioredoxin O2, thioredoxin O2 -0.64 0.32 -0.32
84 AT5G30490 CONTAINS InterPro DOMAIN/s: Craniofacial development
protein 1/Bucentaur (InterPro:IPR011421); Has 333 Blast
hits to 324 proteins in 149 species: Archae - 0; Bacteria -
18; Metazoa - 117; Fungi - 96; Plants - 49; Viruses - 0;
Other Eukaryotes - 53 (source: NCBI BLink).		 -0.64 0.31 -0.3
85 AT3G21540 transducin family protein / WD-40 repeat family protein -0.64 0.31 -0.31
86 AT2G25100 Polynucleotidyl transferase, ribonuclease H-like
superfamily protein		 -0.64 0.3 -0.32
87 AT3G11964 RNA binding;RNA binding -0.64 0.31 -0.32
88 AT5G06360 Ribosomal protein S8e family protein -0.63 0.31 -0.31
89 AT2G40430 CONTAINS InterPro DOMAIN/s: P60-like (InterPro:IPR011687),
Tumour suppressor protein Gltscr2 (InterPro:IPR011211); Has
709 Blast hits to 643 proteins in 201 species: Archae - 0;
Bacteria - 32; Metazoa - 224; Fungi - 154; Plants - 45;
Viruses - 0; Other Eukaryotes - 254 (source: NCBI BLink).		 -0.63 0.3 -0.32
90 AT5G22740 cellulose synthase-like A02 ARABIDOPSIS THALIANA CELLULOSE
SYNTHASE-LIKE A02, ARABIDOPSIS
THALIANA CELLULOSE SYNTHASE-LIKE
A2, cellulose synthase-like A02,
CELLULOSE SYNTHASE-LIKE A 2		 -0.63 0.32 -0.34
91 AT5G22330 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 ATTIP49A, RESISTANCE TO
PSEUDOMONAS SYRINGAE PV MACULICOLA
INTERACTOR 1		 -0.63 0.31 -0.31
92 AT1G80310 sulfate transmembrane transporters molybdate transporter 2 0.63 0.29 -0.31
93 AT4G16670 Plant protein of unknown function (DUF828) with plant
pleckstrin homology-like region		 0.63 0.29 -0.3
94 AT5G18400 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S
biogenesis		 -0.63 0.34 -0.3
95 AT3G26510 Octicosapeptide/Phox/Bem1p family protein 0.63 0.3 -0.34
96 AT3G17790 purple acid phosphatase 17 ATACP5, ATPAP17, purple acid
phosphatase 17		 0.63 0.3 -0.32
97 AT3G02200 Proteasome component (PCI) domain protein -0.63 0.29 -0.33
98 AT3G15610 Transducin/WD40 repeat-like superfamily protein 0.62 0.32 -0.31
99 AT1G07970 CONTAINS InterPro DOMAIN/s: Cytochrome B561-related,
N-terminal (InterPro:IPR019176); Has 215 Blast hits to 213
proteins in 79 species: Archae - 0; Bacteria - 6; Metazoa -
131; Fungi - 22; Plants - 42; Viruses - 0; Other Eukaryotes
- 14 (source: NCBI BLink).		 -0.62 0.32 -0.32
100 AT1G74750 Pentatricopeptide repeat (PPR) superfamily protein -0.62 0.33 -0.32
101 AT5G14760 L-aspartate oxidase L-aspartate oxidase -0.62 0.34 -0.31
102 AT1G68530 3-ketoacyl-CoA synthase 6 ECERIFERUM 6, CUTICULAR 1, G2,
3-ketoacyl-CoA synthase 6,
POLLEN-PISTIL INCOMPATIBILITY 1		 0.62 0.32 -0.3
103 AT4G32400 Mitochondrial substrate carrier family protein ARABIDOPSIS THALIANA BRITTLE 1,
EMBRYO DEFECTIVE 104, EMBRYO
DEFECTIVE 42, SODIUM
HYPERSENSITIVE 1		 -0.62 0.3 -0.31
104 AT1G55150 DEA(D/H)-box RNA helicase family protein -0.62 0.32 -0.31
105 AT3G62970 zinc finger (C3HC4-type RING finger) family protein 0.62 0.3 -0.33
106 AT5G07300 Calcium-dependent phospholipid-binding Copine family
protein		 BONZAI 2 -0.62 0.31 -0.32
107 AT5G67630 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 -0.62 0.31 -0.31
108 AT3G07590 Small nuclear ribonucleoprotein family protein -0.62 0.31 -0.32
109 AT5G14600 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.62 0.29 -0.32
110 AT2G44850 unknown protein; CONTAINS InterPro DOMAIN/s:
Uncharacterised protein family UPF0565
(InterPro:IPR018881); BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT2G45380.1); Has 138 Blast
hits to 138 proteins in 53 species: Archae - 0; Bacteria -
0; Metazoa - 73; Fungi - 0; Plants - 62; Viruses - 0; Other
Eukaryotes - 3 (source: NCBI BLink).		 0.62 0.3 -0.34
111 AT5G62350 Plant invertase/pectin methylesterase inhibitor superfamily
protein		 -0.61 0.33 -0.32
112 AT2G06040 CONTAINS InterPro DOMAIN/s: Leucine-rich repeat,
cysteine-containing subtype (InterPro:IPR006553); BEST
Arabidopsis thaliana protein match is: RNI-like superfamily
protein (TAIR:AT5G21900.1); Has 5028 Blast hits to 2547
proteins in 240 species: Archae - 0; Bacteria - 125;
Metazoa - 2326; Fungi - 765; Plants - 1373; Viruses - 0;
Other Eukaryotes - 439 (source: NCBI BLink).		 -0.61 0.29 -0.33
113 AT3G59800 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT2G43795.2); Has 15361 Blast
hits to 8061 proteins in 537 species: Archae - 2; Bacteria
- 622; Metazoa - 7561; Fungi - 1246; Plants - 920; Viruses
- 49; Other Eukaryotes - 4961 (source: NCBI BLink).		 -0.61 0.31 -0.29
114 AT3G16320 Tetratricopeptide repeat (TPR)-like superfamily protein CDC27a -0.61 0.3 -0.32
115 AT4G26300 Arginyl-tRNA synthetase, class Ic embryo defective 1027 -0.61 0.33 -0.32
116 AT2G41630 transcription factor IIB transcription factor IIB -0.61 0.3 -0.3
117 AT1G62290 Saposin-like aspartyl protease family protein 0.61 0.29 -0.3
118 AT1G48420 D-cysteine desulfhydrase 1-AMINOCYCLOPROPANE-1-CARBOXYLIC
ACID DEAMINASE 1, A. THALIANA
1-AMINOCYCLOPROPANE-1-CARBOXYLIC
ACID DEAMINASE 1, D-cysteine
desulfhydrase, D-cysteine
desulfhydrase		 0.61 0.32 -0.34
119 AT3G27420 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT5G40600.1); Has 43 Blast hits
to 43 proteins in 15 species: Archae - 0; Bacteria - 0;
Metazoa - 3; Fungi - 0; Plants - 39; Viruses - 0; Other
Eukaryotes - 1 (source: NCBI BLink).		 0.61 0.32 -0.31
120 AT5G47930 Zinc-binding ribosomal protein family protein -0.61 0.32 -0.32
121 AT3G12130 KH domain-containing protein / zinc finger (CCCH type)
family protein		 -0.61 0.35 -0.31
122 AT2G46610 RNA-binding (RRM/RBD/RNP motifs) family protein arginine/serine-rich splicing
factor 31a, arginine/serine-rich
splicing factor 31a		 0.61 0.31 -0.32
123 AT3G09720 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 -0.61 0.32 -0.31
124 AT2G20670 Protein of unknown function (DUF506) 0.6 0.3 -0.32
125 AT3G50880 DNA glycosylase superfamily protein 0.6 0.32 -0.31
126 AT5G29000 Homeodomain-like superfamily protein PHR1-like 1 0.6 0.32 -0.3
127 AT2G01680 Ankyrin repeat family protein 0.6 0.3 -0.3
128 AT4G00750 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 0.6 0.32 -0.31
129 AT2G25350 Phox (PX) domain-containing protein 0.6 0.29 -0.32
130 AT5G47560 tonoplast dicarboxylate transporter ATSDAT, TONOPLAST DICARBOXYLATE
TRANSPORTER, tonoplast
dicarboxylate transporter		 0.59 0.32 -0.31
131 AT2G34610 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G30190.1); Has 342 Blast hits
to 279 proteins in 74 species: Archae - 0; Bacteria - 7;
Metazoa - 76; Fungi - 18; Plants - 51; Viruses - 0; Other
Eukaryotes - 190 (source: NCBI BLink).		 0.59 0.32 -0.31
132 AT3G51860 cation exchanger 3 ATCAX3, ATHCX1, CAX1-LIKE, cation
exchanger 3		 0.59 0.29 -0.3
133 AT1G10150 Carbohydrate-binding protein 0.59 0.32 -0.32
134 AT2G18670 RING/U-box superfamily protein 0.59 0.33 -0.29
135 AT5G66110 Heavy metal transport/detoxification superfamily protein heavy metal associated
isoprenylated plant protein 27		 0.59 0.31 -0.33
136 AT1G16730 unknown protein 6 unknown protein 6 0.59 0.31 -0.31
137 AT1G09530 phytochrome interacting factor 3 PHYTOCHROME-ASSOCIATED PROTEIN 3,
phytochrome interacting factor 3,
PHOTOCURRENT 1		 0.59 0.31 -0.31
138 AT5G40890 chloride channel A chloride channel A, ATCLCA,
chloride channel A, CHLORIDE
CHANNEL-A, CHLORIDE CHANNEL A		 0.59 0.31 -0.33
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
139 C0165 MST_1688.6 - - - 0.74 0.48 -0.46
140 C0164 MST_1596.8 - - - 0.73 0.47 -0.48
141 C0160 MST_1509.5 - - - 0.69 0.44 -0.46
142 C0163 MST_1589.2 - - - 0.68 0.41 -0.45
143 C0023 1,6-Anhydro-β-glucose 1,6-Anhydro-β-D-glucose Levoglucosan - 0.68 0.45 -0.45 C0023
144 C0161 MST_1566.3 - - - 0.65 0.47 -0.45