4.0:Information of module
IPT8 induced 12h
In comparison with IAA7mII over-expressor IAA Treated help
Scatter plot of seleted modules.
Trend of Up regulated genes including module
GOID Term Ontology p-value
GO:0009812 flavonoid metabolic process BP 7.236e-10
GO:0042221 response to chemical BP 1.121e-08
GO:1901700 response to oxygen-containing compound BP 1.532e-08
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View Hierarchical networks of GOs (      )
Trend of Down regulated genes including module
GOID Term Ontology p-value
GO:0032259 methylation BP 4.153e-29
GO:0043414 macromolecule methylation BP 6.432e-29
GO:0001510 RNA methylation BP 7.347e-25
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View Hierarchical networks of GOs (      )
List of genes in module
･･･up requlated genes  ･･･down regulated genes
probeID AGICode Annotation Log2 signal ratio
IPT8 induced 12h		 Log2 signal ratio
IAA7mII over-expressor IAA Treated
1 257039_at AT3G19160 ATIPT8, ATP/ADP isopentenyltransferases, IPT8, ATP/ADP isopentenyltransferases, IPT8, isopentenyltransferase 8, PGA22 1.358 0.097
2 266078_at AT2G40670 ARR16, response regulator 16, RR16, response regulator 16 0.839 0.634
3 259388_at AT1G13420 ATST4B, ARABIDOPSIS THALIANA SULFOTRANSFERASE 4B, ST4B, sulfotransferase 4B 0.826 -0.004
4 256602_at AT3G28310 unknown 0.778 0.074
5 256631_at AT3G28320 unknown 0.714 0.068
6 246825_at AT5G26260 [TRAF-like family protein] 0.691 -0.009
7 259846_at AT1G72140 [Major facilitator superfamily protein] 0.690 -0.238
8 247754_at AT5G59080 unknown 0.689 0.082
9 245353_at AT4G16000 unknown 0.675 0.139
10 264404_at AT2G25160 CYP82F1, cytochrome P450, family 82, subfamily F, polypeptide 1 0.669 0.104
11 248729_at AT5G48010 AtTHAS1, Arabidopsis thaliana thalianol synthase 1, THAS, THALIANOL SYNTHASE, THAS1, thalianol synthase 1 0.620 0.263
12 247657_at AT5G59845 [Gibberellin-regulated family protein] 0.607 0.167
13 260438_at AT1G68290 ENDO2, endonuclease 2 0.606 0.094
14 259897_at AT1G71380 ATCEL3, cellulase 3, ATGH9B3, ARABIDOPSIS THALIANA GLYCOSYL HYDROLASE 9B3, CEL3, cellulase 3 0.597 -0.024
15 257735_at AT3G27400 [Pectin lyase-like superfamily protein] 0.553 0.096
16 245713_at AT5G04370 NAMT1 0.540 0.043
17 254907_at AT4G11190 [Disease resistance-responsive (dirigent-like protein) family protein] 0.536 0.164
18 262704_at AT1G16530 ASL9, ASYMMETRIC LEAVES 2-like 9, LBD3, LOB DOMAIN-CONTAINING PROTEIN 3 0.515 0.033
19 250223_at AT5G14070 ROXY2 0.514 0.055
20 258760_at AT3G10780 [emp24/gp25L/p24 family/GOLD family protein] 0.498 0.479
21 263380_at AT2G40200 [basic helix-loop-helix (bHLH) DNA-binding superfamily protein] 0.492 0.113
22 262915_at AT1G59940 ARR3, response regulator 3 0.476 0.224
23 253696_at AT4G29740 ATCKX4, CKX4, cytokinin oxidase 4 0.476 0.115
24 253839_at AT4G27890 [HSP20-like chaperones superfamily protein] 0.475 0.029
25 264138_at AT1G78950 AtBAS, AtLUP4, BAS, beta-amyrin synthase 0.466 0.045
26 248723_at AT5G47950 [HXXXD-type acyl-transferase family protein] 0.464 0.207
27 264436_at AT1G10370 ATGSTU17, GLUTATHIONE S-TRANSFERASE TAU 17, ERD9, EARLY-RESPONSIVE TO DEHYDRATION 9, GST30, GLUTATHIONE S-TRANSFERASE 30, GST30B, GLUTATHIONE S-TRANSFERASE 30B, GSTU17, GLUTATHIONE S-TRANSFERASE U17 0.460 0.076
28 248728_at AT5G48000 CYP708 A2, CYTOCHROME P450, FAMILY 708, SUBFAMILY A, POLYPEPTIDE 2, CYP708A2, cytochrome P450, family 708, subfamily A, polypeptide 2, THAH, THALIANOL HYDROXYLASE, THAH1, THALIANOL HYDROXYLASE 1 0.460 0.277
29 251466_at AT3G59340 unknown 0.458 0.031
30 248725_at AT5G47980 [HXXXD-type acyl-transferase family protein] 0.456 0.316
31 266418_at AT2G38750 ANNAT4, annexin 4, AtANN4 0.453 0.089
32 264790_at AT2G17820 AHK1, ATHK1, histidine kinase 1, HK1, histidine kinase 1 0.452 0.063
33 248727_at AT5G47990 CYP705A5, cytochrome P450, family 705, subfamily A, polypeptide 5, THAD, THALIAN-DIOL DESATURASE, THAD1, THALIAN-DIOL DESATURASE 0.443 0.210
34 255385_at AT4G03610 [Metallo-hydrolase/oxidoreductase superfamily protein] 0.436 0.045
35 253819_at AT4G28350 LecRK-VII.2, L-type lectin receptor kinase VII.2 0.426 0.133
36 247228_at AT5G65140 TPPJ, trehalose-6-phosphate phosphatase J 0.422 -0.253
37 259586_at AT1G28100 unknown 0.420 -0.008
38 254111_at AT4G24890 ATPAP24, ARABIDOPSIS THALIANA PURPLE ACID PHOSPHATASE 24, PAP24, purple acid phosphatase 24 0.411 0.328
39 259653_at AT1G55240 unknown 0.397 0.384
40 247956_at AT5G56970 ATCKX3, CKX3, cytokinin oxidase 3 0.393 0.105
41 257467_at AT1G31320 LBD4, LOB domain-containing protein 4 0.393 0.043
42 256713_at AT2G34060 [Peroxidase superfamily protein] 0.380 0.176
43 251858_at AT3G54820 PIP2;5, plasma membrane intrinsic protein 2;5, PIP2D, PLASMA MEMBRANE INTRINSIC PROTEIN 2D 0.374 0.111
44 262516_at AT1G17190 ATGSTU26, glutathione S-transferase tau 26, GSTU26, glutathione S-transferase tau 26 0.372 -0.039
45 249750_at AT5G24570 unknown 0.372 0.492
46 258901_at AT3G05640 [Protein phosphatase 2C family protein] 0.371 0.277
47 267058_at AT2G32510 MAPKKK17, mitogen-activated protein kinase kinase kinase 17 0.369 0.613
48 258938_at AT3G10080 [RmlC-like cupins superfamily protein] 0.366 0.053
49 248118_at AT5G55050 [GDSL-like Lipase/Acylhydrolase superfamily protein] 0.364 0.115
50 253774_at AT4G28530 anac074, NAC domain containing protein 74, NAC074, NAC domain containing protein 74 0.362 0.567
51 245560_at AT4G15480 UGT84A1 0.360 0.156
52 267012_at AT2G39220 PLA IIB, PLP6, PATATIN-like protein 6 0.359 0.135
53 246485_at AT5G16080 AtCXE17, carboxyesterase 17, CXE17, carboxyesterase 17 0.359 0.082
54 264527_at AT1G30760 [FAD-binding Berberine family protein] 0.349 -0.038
55 258618_at AT3G02885 GASA5, GAST1 protein homolog 5 0.348 0.044
56 252639_at AT3G44550 FAR5, fatty acid reductase 5 0.343 0.143
57 246833_at AT5G26620 unknown 0.330 0.173
58 261934_at AT1G22400 ATUGT85A1, ARABIDOPSIS THALIANA UDP-GLUCOSYL TRANSFERASE 85A1, UGT85A1 0.329 0.211
59 246395_at AT1G58170 [Disease resistance-responsive (dirigent-like protein) family protein] 0.328 0.198
60 247005_at AT5G67520 adenosine-5'-phosphosulfate (APS) kinase 4 0.327 -0.310
61 263211_at AT1G10460 GLP7, germin-like protein 7 0.326 0.114
62 264501_at AT1G09390 [GDSL-like Lipase/Acylhydrolase superfamily protein] 0.321 0.380
63 250413_at AT5G11160 APT5, adenine phosphoribosyltransferase 5 0.320 0.133
64 246488_at AT5G16010 [3-oxo-5-alpha-steroid 4-dehydrogenase family protein] 0.316 0.086
65 259466_at AT1G19050 ARR7, response regulator 7 0.316 0.128
66 247867_at AT5G57630 CIPK21, CBL-interacting protein kinase 21, SnRK3.4, SNF1-RELATED PROTEIN KINASE 3.4 0.315 0.050
67 254828_at AT4G12550 AIR1, Auxin-Induced in Root cultures 1 0.315 -0.045
68 245319_at AT4G16146 [cAMP-regulated phosphoprotein 19-related protein] 0.313 0.039
69 254453_at AT4G21120 AAT1, amino acid transporter 1, CAT1, CATIONIC AMINO ACID TRANSPORTER 1 0.313 0.167
70 261907_at AT1G65060 4CL3, 4-coumarate:CoA ligase 3 0.311 0.173
71 245710_at AT5G04330 CYP84A4, CYTOCHROME P450 84A4 0.310 0.034
72 258252_at AT3G15720 [Pectin lyase-like superfamily protein] 0.308 0.183
73 263948_at AT2G35980 ATNHL10, ARABIDOPSIS NDR1/HIN1-LIKE 10, NHL10, NDR1/HIN1-LIKE, YLS9, YELLOW-LEAF-SPECIFIC GENE 9 0.306 0.053
74 254213_at AT4G23590 [Tyrosine transaminase family protein] 0.304 -0.120
75 252202_at AT3G50300 [HXXXD-type acyl-transferase family protein] 0.303 -0.172
76 247406_at AT5G62920 ARR6, response regulator 6 0.303 -0.014
77 253042_at AT4G37550 [Acetamidase/Formamidase family protein] 0.303 -0.795
78 256968_at AT3G21070 ATNADK-1, NAD KINASE 1, NADK1, NAD kinase 1 0.301 0.329
79 246203_at AT4G36610 [alpha/beta-Hydrolases superfamily protein] 0.297 0.087
80 250054_at AT5G17860 CAX7, calcium exchanger 7 0.295 -0.001
81 257442_at AT2G28680 [RmlC-like cupins superfamily protein] 0.291 0.230
82 262922_at AT1G79420 unknown 0.287 0.204
83 267344_at AT2G44230 unknown 0.286 -0.024
84 262940_at AT1G79520 [Cation efflux family protein] 0.285 0.304
85 248153_at AT5G54250 ATCNGC4, cyclic nucleotide-gated cation channel 4, CNGC4, cyclic nucleotide-gated cation channel 4, DND2, DEFENSE, NO DEATH 2, HLM1 0.279 0.202
86 246389_at AT1G77380 AAP3, amino acid permease 3, ATAAP3 0.277 0.020
87 250860_at AT5G04770 ATCAT6, ARABIDOPSIS THALIANA CATIONIC AMINO ACID TRANSPORTER 6, CAT6, cationic amino acid transporter 6 0.276 -0.021
88 252123_at AT3G51240 F3'H, F3H, flavanone 3-hydroxylase, TT6, TRANSPARENT TESTA 6 0.274 -0.577
89 247610_at AT5G60630 unknown 0.272 0.134
90 254474_at AT4G20390 [Uncharacterised protein family (UPF0497)] 0.272 0.098
91 252374_at AT3G48100 ARR5, response regulator 5, ATRR2, ARABIDOPSIS THALIANA RESPONSE REGULATOR 2, IBC6, INDUCED BY CYTOKININ 6, RR5, response regulator 5 0.269 -0.465
92 245347_at AT4G14890 FdC1, ferredoxin C 1 0.267 0.052
93 266072_at AT2G18700 ATTPS11, trehalose phosphatase/synthase 11, ATTPSB, TPS11, trehalose phosphatase/synthase 11, TPS11, TREHALOSE-6-PHOSPHATE SYNTHASE 11 0.261 0.064
94 253496_at AT4G31870 ATGPX7, GLUTATHIONE PEROXIDASE 7, GPX7, glutathione peroxidase 7 0.261 0.152
95 263737_at AT1G60010 unknown 0.257 -0.515
96 266352_at AT2G01610 [Plant invertase/pectin methylesterase inhibitor superfamily protein] 0.256 0.053
97 259129_at AT3G02150 PTF1, plastid transcription factor 1, TCP13, TEOSINTE BRANCHED1, CYCLOIDEA AND PCF TRANSCRIPTION FACTOR 13, TFPD 0.256 0.570
98 247136_at AT5G66170 STR18, sulfurtransferase 18 0.255 0.021
99 258287_at AT3G15990 SULTR3;4, sulfate transporter 3;4 0.254 0.001
100 245385_at AT4G14020 [Rapid alkalinization factor (RALF) family protein] -0.765 0.055
101 246229_at AT4G37160 sks15, SKU5 similar 15 -0.731 0.067
102 266209_at AT2G27550 ATC, centroradialis -0.714 0.208
103 261576_at AT1G01070 UMAMIT28, Usually multiple acids move in and out Transporters 28 -0.694 0.069
104 260076_at AT1G73630 [EF hand calcium-binding protein family] -0.659 0.136
105 262883_at AT1G64780 AMT1;2, ammonium transporter 1;2, ATAMT1;2, ammonium transporter 1;2 -0.617 0.060
106 250469_at AT5G10130 [Pollen Ole e 1 allergen and extensin family protein] -0.612 0.179
107 247634_at AT5G60520 [Late embryogenesis abundant (LEA) protein-related] -0.612 0.149
108 248178_at AT5G54370 [Late embryogenesis abundant (LEA) protein-related] -0.567 -0.023
109 247337_at AT5G63660 LCR74, LOW-MOLECULAR-WEIGHT CYSTEINE-RICH 74, PDF2.5 -0.565 0.133
110 265246_at AT2G43050 ATPMEPCRD -0.562 0.154
111 261004_at AT1G26450 [Carbohydrate-binding X8 domain superfamily protein] -0.540 0.117
112 256349_at AT1G54890 [Late embryogenesis abundant (LEA) protein-related] -0.537 0.060
113 265769_at AT2G48090 unknown -0.517 0.228
114 256593_at AT3G28510 [P-loop containing nucleoside triphosphate hydrolases superfamily protein] -0.511 0.037
115 246149_at AT5G19890 [Peroxidase superfamily protein] -0.504 0.134
116 246585_at AT5G14750 ATMYB66, myb domain protein 66, MYB66, myb domain protein 66, WER, WEREWOLF, WER1, WEREWOLF 1 -0.496 -0.128
117 261985_at AT1G33750 [Terpenoid cyclases/Protein prenyltransferases superfamily protein] -0.493 0.286
118 257375_at AT2G38640 unknown -0.491 0.049
119 267141_at AT2G38090 [Duplicated homeodomain-like superfamily protein] -0.481 -0.206
120 253483_at AT4G31910 BAT1, BR-related AcylTransferase1, PIZ, PIZZA -0.465 0.192
121 247094_at AT5G66280 GMD1, GDP-D-mannose 4,6-dehydratase 1 -0.458 -0.160
122 260144_at AT1G71960 ABCG25, ATP-binding casette G25, ATABCG25, Arabidopsis thaliana ATP-binding cassette G25 -0.457 0.134
123 250214_at AT5G13870 EXGT-A4, endoxyloglucan transferase A4, XTH5, xyloglucan endotransglucosylase/hydrolase 5 -0.453 0.038
124 262396_at AT1G49470 unknown -0.443 0.056
125 260230_at AT1G74500 ATBS1, activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1, bHLH135, basic helix-loop-helix protein 135, BS1, activation-tagged BRI1(brassinosteroid-insensitive 1)-suppressor 1, PRE3, PACLOBUTRAZOL RESISTANCE 3, TMO7, TARGET OF MONOPTEROS 7 -0.438 0.056
126 250002_at AT5G18690 AGP25, arabinogalactan protein 25, ATAGP25, ARABIDOPSIS THALIANA ARABINOGALACTAN PROTEINS 25 -0.424 0.130
127 264565_at AT1G05280 unknown -0.421 0.362
128 255016_at AT4G10120 ATSPS4F -0.420 0.107
129 259813_at AT1G49860 ATGSTF14, glutathione S-transferase (class phi) 14, GSTF14, glutathione S-transferase (class phi) 14 -0.412 0.070
130 247070_at AT5G66815 unknown -0.406 0.193
131 262154_at AT1G52700 [alpha/beta-Hydrolases superfamily protein] -0.402 0.203
132 266222_at AT2G28780 unknown -0.400 -0.097
133 262728_at AT1G75820 ATCLV1, CLV1, CLAVATA 1, FAS3, FASCIATA 3, FLO5, FLOWER DEVELOPMENT 5 -0.399 -0.107
134 261504_at AT1G71692 AGL12, AGAMOUS-like 12, XAL1, XAANTAL1 -0.385 0.011
135 245463_at AT4G17030 AT-EXPR, ATEXLB1, expansin-like B1, ATEXPR1, ATHEXP BETA 3.1, EXLB1, expansin-like B1, EXPR -0.384 0.195
136 250892_at AT5G03760 ATCSLA09, ATCSLA9, CSLA09, CSLA9, CELLULOSE SYNTHASE LIKE A9, RAT4, RESISTANT TO AGROBACTERIUM TRANSFORMATION 4 -0.379 0.194
137 247753_at AT5G59070 [UDP-Glycosyltransferase superfamily protein] -0.379 -0.009
138 262446_at AT1G49310 unknown -0.374 -0.004
139 248777_at AT5G47920 unknown -0.373 0.133
140 264734_at AT1G62280 SLAH1, SLAC1 homologue 1 -0.372 0.183
141 257105_at AT3G15300 [VQ motif-containing protein] -0.371 -0.245
142 253657_at AT4G30110 ATHMA2, ARABIDOPSIS HEAVY METAL ATPASE 2, HMA2, heavy metal atpase 2 -0.369 0.179
143 247922_at AT5G57500 [Galactosyltransferase family protein] -0.369 -0.238
144 247474_at AT5G62280 unknown -0.366 -0.161
145 263373_at AT2G20515 unknown -0.362 0.093
146 245172_at AT2G47540 [Pollen Ole e 1 allergen and extensin family protein] -0.360 -0.228
147 263481_at AT2G04025 GLV7, GOLVEN 7, RGF3, root meristem growth factor 3 -0.356 0.089
148 262045_at AT1G80240 DGR1, DUF642 L-GalL responsive gene 1 -0.352 -0.198
149 246016_at AT5G10720 AHK5, histidine kinase 5, CKI2, CYTOKININ INDEPENDENT 2, HK5, histidine kinase 5 -0.350 -0.284
150 258293_at AT3G23430 ATPHO1, ARABIDOPSIS PHOSPHATE 1, PHO1, phosphate 1 -0.342 0.097
151 251324_at AT3G61430 ATPIP1, ARABIDOPSIS THALIANA PLASMA MEMBRANE INTRINSIC PROTEIN 1, PIP1, PLASMA MEMBRANE INTRINSIC PROTEIN 1, PIP1;1, PLASMA MEMBRANE INTRINSIC PROTEIN 1;1, PIP1A, plasma membrane intrinsic protein 1A -0.338 0.076
152 249136_at AT5G43180 unknown -0.338 -0.036
153 265856_at AT2G42430 ASL18, ASYMMETRIC LEAVES2-LIKE 18, LBD16, lateral organ boundaries-domain 16 -0.336 -0.352
154 263867_at AT2G36830 GAMMA-TIP, gamma tonoplast intrinsic protein, GAMMA-TIP1, GAMMA TONOPLAST INTRINSIC PROTEIN 1, TIP1;1, TONOPLAST INTRINSIC PROTEIN 1;1 -0.332 -0.020
155 246390_at AT1G77330 ACO5, ACC oxidase 5 -0.323 0.008
156 264696_at AT1G70230 AXY4, ALTERED XYLOGLUCAN 4, TBL27, TRICHOME BIREFRINGENCE-LIKE 27 -0.323 0.119
157 259632_at AT1G56430 ATNAS4, ARABIDOPSIS THALIANA NICOTIANAMINE SYNTHASE 4, NAS4, nicotianamine synthase 4 -0.322 0.079
158 248104_at AT5G55250 AtIAMT1, IAMT1, IAA carboxylmethyltransferase 1 -0.317 0.176
159 246415_at AT5G17160 unknown -0.315 0.169
160 261327_at AT1G44830 [Integrase-type DNA-binding superfamily protein] -0.314 0.206
161 258270_at AT3G15650 [alpha/beta-Hydrolases superfamily protein] -0.309 0.115
162 250438_at AT5G10580 unknown -0.307 0.128
163 261660_at AT1G18370 ATNACK1, ARABIDOPSIS NPK1-ACTIVATING KINESIN 1, HIK, HINKEL, NACK1, NPK1-ACTIVATING KINESIN 1 -0.304 0.109
164 258867_at AT3G03130 unknown -0.298 0.051
165 260059_at AT1G78090 ATTPPB, Arabidopsis thaliana trehalose-6-phosphate phosphatase B, TPPB, trehalose-6-phosphate phosphatase B -0.295 0.127
166 257740_at AT3G27330 [zinc finger (C3HC4-type RING finger) family protein] -0.294 0.181
167 266546_at AT2G35270 AHL21, AT-hook motif nuclear localized protein 21, GIK, GIANT KILLER -0.291 0.016
168 247739_at AT5G59240 [Ribosomal protein S8e family protein] -0.288 -0.008
169 254235_at AT4G23750 CRF2, cytokinin response factor 2, TMO3, TARGET OF MONOPTEROS 3 -0.287 0.095
170 246001_at AT5G20790 unknown -0.285 0.338
171 263914_at AT2G36400 AtGRF3, growth-regulating factor 3, GRF3, growth-regulating factor 3 -0.280 -0.041
172 261636_at AT1G50110 [D-aminoacid aminotransferase-like PLP-dependent enzymes superfamily protein] -0.278 0.098
173 261221_at AT1G19960 unknown -0.275 0.140
174 251900_at AT3G54430 SRS6, SHI-related sequence 6 -0.274 0.228
175 247645_at AT5G60530 [late embryogenesis abundant protein-related / LEA protein-related] -0.269 0.005
176 263360_at AT2G03830 GLV6, GOLVEN 6, RGF8, root meristem growth factor 8 -0.267 0.089
177 251174_at AT3G63200 PLA IIIB, PLP9, PATATIN-like protein 9 -0.265 0.153
178 267636_at AT2G42110 unknown -0.265 0.280
179 258397_at AT3G15357 unknown -0.264 0.002
180 262231_at AT1G68740 PHO1;H1 -0.260 0.149
181 266561_at AT2G23960 [Class I glutamine amidotransferase-like superfamily protein] -0.259 0.344
182 248535_at AT5G50120 [Transducin/WD40 repeat-like superfamily protein] -0.258 0.233
183 247038_at AT5G67160 EPS1, ENHANCED PSEUDOMONAS SUSCEPTIBILTY 1 -0.257 0.066
184 257487_at AT1G71850 [Ubiquitin carboxyl-terminal hydrolase family protein] -0.256 0.025
185 251394_at AT3G60900 FLA10, FASCICLIN-like arabinogalactan-protein 10 -0.255 0.195
186 263318_at AT2G24762 AtGDU4, glutamine dumper 4, GDU4, glutamine dumper 4 -0.253 0.155
187 256926_at AT3G22540 unknown -0.250 0.234
188 253051_at AT4G37490 CYC1, CYCLIN 1, CYCB1, CYCB1;1, CYCLIN B1;1 -0.248 0.016
189 254233_at AT4G23800 3xHMG-box2, 3xHigh Mobility Group-box2 -0.247 -0.188
190 264895_at AT1G23100 [GroES-like family protein] -0.245 0.264
191 249874_at AT5G23070 AtTK1b, TK1b, thymidine kinase 1b -0.244 -0.115
192 249214_at AT5G42720 [Glycosyl hydrolase family 17 protein] -0.243 0.054
193 260539_at AT2G43480 [Peroxidase superfamily protein] -0.242 0.184
194 245891_at AT5G09220 AAP2, amino acid permease 2 -0.242 0.142
195 253332_at AT4G33420 [Peroxidase superfamily protein] -0.240 0.203
196 266663_at AT2G25790 SKM1, STERILITY-REGULATING KINASE MEMBER 1 -0.240 0.076
197 262743_at AT1G29020 [Calcium-binding EF-hand family protein] -0.236 0.145