AT5G08280 : hydroxymethylbilane synthase
Query Information
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AGICode AT5G08280
Description hydroxymethylbilane synthase
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT5G08280 hydroxymethylbilane synthase hydroxymethylbilane synthase 1 0.32 -0.32
2 AT2G40490 Uroporphyrinogen decarboxylase HEME2 0.96 0.31 -0.32
3 AT2G43030 Ribosomal protein L3 family protein 0.96 0.34 -0.32
4 AT1G64510 Translation elongation factor EF1B/ribosomal protein S6
family protein		 0.96 0.33 -0.32
5 AT5G58250 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
thylakoid, chloroplast; EXPRESSED IN: 22 plant structures;
EXPRESSED DURING: 14 growth stages; CONTAINS InterPro
DOMAIN/s: Protein of unknown function DUF2488
(InterPro:IPR019616); Has 1807 Blast hits to 1807 proteins
in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736;
Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes -
339 (source: NCBI BLink).		 EMBRYO DEFECTIVE 3143 0.95 0.31 -0.28
6 AT3G54210 Ribosomal protein L17 family protein 0.95 0.31 -0.3
7 AT5G11480 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 0.95 0.31 -0.32
8 AT3G13120 Ribosomal protein S10p/S20e family protein 0.95 0.31 -0.31
9 AT2G33800 Ribosomal protein S5 family protein EMBRYO DEFECTIVE 3113 0.95 0.32 -0.32
10 AT3G48730 glutamate-1-semialdehyde 2,1-aminomutase 2 glutamate-1-semialdehyde
2,1-aminomutase 2		 0.95 0.33 -0.32
11 AT3G52150 RNA-binding (RRM/RBD/RNP motifs) family protein 0.95 0.32 -0.3
12 AT5G65220 Ribosomal L29 family protein 0.94 0.31 -0.33
13 AT2G33450 Ribosomal L28 family 0.94 0.33 -0.29
14 AT1G75350 Ribosomal protein L31 embryo defective 2184 0.94 0.32 -0.31
15 AT3G12930 Lojap-related protein 0.94 0.31 -0.29
16 AT5G14320 Ribosomal protein S13/S18 family EMBRYO DEFECTIVE 3137 0.94 0.31 -0.32
17 AT4G37510 Ribonuclease III family protein 0.94 0.33 -0.33
18 AT5G47190 Ribosomal protein L19 family protein 0.94 0.33 -0.31
19 AT4G34290 SWIB/MDM2 domain superfamily protein 0.93 0.31 -0.33
20 AT2G35500 shikimate kinase like 2 shikimate kinase-like 2 0.93 0.32 -0.33
21 AT3G28460 methyltransferases 0.93 0.31 -0.33
22 AT1G07320 ribosomal protein L4 EMBRYO DEFECTIVE 2784, ribosomal
protein L4		 0.93 0.31 -0.3
23 AT4G11175 Nucleic acid-binding, OB-fold-like protein 0.93 0.32 -0.31
24 AT2G48070 resistance to phytophthora 1 RESISTANCE TO PHYTOPHTHORA 1 0.93 0.3 -0.32
25 AT1G48350 Ribosomal L18p/L5e family protein EMBRYO DEFECTIVE 3105 0.93 0.31 -0.31
26 AT4G34620 small subunit ribosomal protein 16 small subunit ribosomal protein 16 0.93 0.31 -0.31
27 AT1G05190 Ribosomal protein L6 family embryo defective 2394 0.93 0.32 -0.32
28 AT3G25920 ribosomal protein L15 ribosomal protein L15 0.93 0.31 -0.33
29 AT1G02150 Tetratricopeptide repeat (TPR)-like superfamily protein 0.93 0.31 -0.33
30 AT1G79850 ribosomal protein S17 CS17, PIGMENT DEFECTIVE 347,
PLASTID RIBOSOMAL SMALL SUBUNIT
PROTEIN 17, ribosomal protein S17		 0.93 0.3 -0.3
31 AT3G56910 plastid-specific 50S ribosomal protein 5 plastid-specific 50S ribosomal
protein 5		 0.93 0.32 -0.32
32 AT4G20130 plastid transcriptionally active 14 plastid transcriptionally active
14		 0.92 0.32 -0.3
33 AT5G45930 magnesium chelatase i2 CHL I2, CHLI-2, magnesium
chelatase i2		 0.92 0.32 -0.34
34 AT2G40690 NAD-dependent glycerol-3-phosphate dehydrogenase family
protein		 GLY1, SUPPRESSOR OF FATTY ACID
DESATURASE DEFICIENCY 1		 0.92 0.33 -0.29
35 AT4G26370 antitermination NusB domain-containing protein 0.92 0.32 -0.29
36 AT5G14910 Heavy metal transport/detoxification superfamily protein 0.92 0.33 -0.3
37 AT5G14660 peptide deformylase 1B ATDEF2, DEF2, peptide deformylase
1B		 0.92 0.33 -0.31
38 AT1G35680 Ribosomal protein L21 chloroplast ribosomal protein L21 0.92 0.32 -0.32
39 AT3G14930 Uroporphyrinogen decarboxylase HEME1 0.92 0.31 -0.32
40 AT1G68590 Ribosomal protein PSRP-3/Ycf65 0.92 0.31 -0.34
41 AT1G14270 CAAX amino terminal protease family protein 0.92 0.31 -0.32
42 AT4G18480 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 CHLORINA 42, CHLORINA 42, CHL11,
CHLI-1, CHLI1		 0.92 0.31 -0.34
43 AT5G13510 Ribosomal protein L10 family protein EMBRYO DEFECTIVE 3136 0.92 0.33 -0.3
44 AT2G18710 SECY homolog 1 SECY homolog 1 0.92 0.31 -0.33
45 AT1G08540 RNApolymerase sigma subunit 2 ABC1, SIGMA FACTOR 1, SIGMA FACTOR
2, RNA POLYMERASE SIGMA SUBUNIT 1,
RNApolymerase sigma subunit 2,
SIGA, SIGMA FACTOR B		 0.92 0.32 -0.32
46 AT3G05600 alpha/beta-Hydrolases superfamily protein 0.92 0.32 -0.3
47 AT5G19620 outer envelope protein of 80 kDa ARABIDOPSIS THALIANA OUTER
ENVELOPE PROTEIN OF 80 KDA, EMBRYO
DEFECTIVE 213, outer envelope
protein of 80 kDa, translocon at
the outer envelope membrane of
chloroplasts 75-V		 0.92 0.34 -0.3
48 AT5G52960 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED
DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s:
Protein of unknown function DUF3143 (InterPro:IPR021489);
Has 1807 Blast hits to 1807 proteins in 277 species: Archae
- 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants -
385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI
BLink).		 0.91 0.3 -0.34
49 AT1G32990 plastid ribosomal protein l11 plastid ribosomal protein l11 0.91 0.32 -0.31
50 AT3G15190 chloroplast 30S ribosomal protein S20, putative 0.91 0.33 -0.32
51 AT1G78630 Ribosomal protein L13 family protein embryo defective 1473 0.91 0.33 -0.31
52 AT1G53520 Chalcone-flavanone isomerase family protein 0.91 0.29 -0.3
53 AT2G33180 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast stroma; EXPRESSED IN: 22 plant structures;
EXPRESSED DURING: 13 growth stages; Has 57 Blast hits to 57
proteins in 22 species: Archae - 0; Bacteria - 8; Metazoa -
0; Fungi - 0; Plants - 35; Viruses - 0; Other Eukaryotes -
14 (source: NCBI BLink).		 0.91 0.3 -0.32
54 AT5G63050 embryo defective 2759 embryo defective 2759 0.91 0.32 -0.31
55 AT5G38290 Peptidyl-tRNA hydrolase family protein 0.91 0.32 -0.32
56 AT3G04260 plastid transcriptionally active 3 PIGMENT DEFECTIVE 324, plastid
transcriptionally active 3		 0.91 0.32 -0.34
57 AT1G67740 photosystem II BY photosystem II BY, YCF32 0.91 0.33 -0.29
58 AT5G46420 16S rRNA processing protein RimM family 0.91 0.32 -0.3
59 AT1G06190 Rho termination factor 0.9 0.3 -0.31
60 AT4G17560 Ribosomal protein L19 family protein 0.9 0.31 -0.32
61 AT3G29185 Domain of unknown function (DUF3598) 0.9 0.3 -0.33
62 AT2G45270 glycoprotease 1 glycoprotease 1 0.9 0.32 -0.32
63 AT5G23310 Fe superoxide dismutase 3 Fe superoxide dismutase 3 0.9 0.31 -0.32
64 AT4G17600 Chlorophyll A-B binding family protein LIL3:1 0.9 0.33 -0.31
65 AT1G08520 ALBINA 1 ALB-1V, ALBINA 1, CHLD, PIGMENT
DEFECTIVE EMBRYO 166, V157		 0.9 0.31 -0.32
66 AT3G06730 Thioredoxin z thioredoxin putative plastidic,
Thioredoxin z		 0.9 0.31 -0.31
67 AT3G09210 plastid transcriptionally active 13 plastid transcriptionally active
13		 0.9 0.3 -0.32
68 AT2G24060 Translation initiation factor 3 protein 0.9 0.31 -0.31
69 AT5G16140 Peptidyl-tRNA hydrolase family protein 0.9 0.33 -0.32
70 AT3G25480 Rhodanese/Cell cycle control phosphatase superfamily
protein		 0.9 0.31 -0.32
71 AT5G30510 ribosomal protein S1 ARRPS1, ribosomal protein S1 0.9 0.3 -0.3
72 AT5G52970 thylakoid lumen 15.0 kDa protein 0.9 0.31 -0.31
73 AT3G63410 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 ALBINO OR PALE GREEN MUTANT 1,
E37, INNER ENVELOPE PROTEIN 37,
VITAMIN E DEFECTIVE 3		 0.9 0.34 -0.3
74 AT3G44890 ribosomal protein L9 ribosomal protein L9 0.9 0.31 -0.32
75 AT1G11430 plastid developmental protein DAG, putative 0.89 0.3 -0.31
76 AT2G33430 differentiation and greening-like 1 DIFFERENTIATION AND GREENING-LIKE,
differentiation and greening-like
1		 0.89 0.31 -0.33
77 AT1G01080 RNA-binding (RRM/RBD/RNP motifs) family protein 0.89 0.31 -0.33
78 AT2G30695 FUNCTIONS IN: molecular_function unknown; INVOLVED IN:
protein folding, protein transport; LOCATED IN: chloroplast
stroma, chloroplast; EXPRESSED IN: 23 plant structures;
EXPRESSED DURING: 13 growth stages; CONTAINS InterPro
DOMAIN/s: Trigger factor, ribosome-binding, bacterial
(InterPro:IPR008881); Has 253 Blast hits to 253 proteins in
72 species: Archae - 0; Bacteria - 138; Metazoa - 0; Fungi
- 0; Plants - 40; Viruses - 0; Other Eukaryotes - 75
(source: NCBI BLink).		 0.89 0.31 -0.32
79 AT4G01310 Ribosomal L5P family protein 0.89 0.3 -0.31
80 AT4G20360 RAB GTPase homolog E1B ATRAB8D, RAB GTPase homolog E1B,
RAB GTPase homolog E1B		 0.89 0.32 -0.32
81 AT3G17170 Translation elongation factor EF1B/ribosomal protein S6
family protein		 REGULATOR OF FATTY-ACID
COMPOSITION 3		 0.89 0.31 -0.32
82 AT1G01970 Tetratricopeptide repeat (TPR)-like superfamily protein 0.89 0.27 -0.33
83 AT4G27600 pfkB-like carbohydrate kinase family protein GENES NECESSARY FOR THE
ACHIEVEMENT OF RUBISCO
ACCUMULATION 5		 0.89 0.31 -0.32
84 AT5G44650 Encodes a chloroplast protein that induces tolerance to
multiple environmental stresses and reduces photooxidative
damage.		 Arabidopsis thaliana chloroplast
protein-enhancing stress
tolerance, chloroplast
protein-enhancing stress
tolerance, Ycf3-interacting
protein 1		 0.89 0.3 -0.28
85 AT2G41950 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast, plant-type cell wall; EXPRESSED IN: 22 plant
structures; EXPRESSED DURING: 13 growth stages; Has 53
Blast hits to 53 proteins in 24 species: Archae - 0;
Bacteria - 27; Metazoa - 0; Fungi - 0; Plants - 26; Viruses
- 0; Other Eukaryotes - 0 (source: NCBI BLink).		 0.89 0.33 -0.3
86 AT4G28210 embryo defective 1923 embryo defective 1923 0.89 0.3 -0.31
87 AT2G38140 plastid-specific ribosomal protein 4 plastid-specific ribosomal protein
4		 0.89 0.32 -0.31
88 AT5G51110 Transcriptional coactivator/pterin dehydratase 0.89 0.32 -0.29
89 AT4G01690 Flavin containing amine oxidoreductase family HEMG1, PPO1, PPOX 0.89 0.31 -0.29
90 AT5G55220 trigger factor type chaperone family protein 0.89 0.31 -0.33
91 AT1G64355 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED
DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s:
Protein of unknown function DUF3593 (InterPro:IPR021995);
Has 301 Blast hits to 301 proteins in 96 species: Archae -
0; Bacteria - 143; Metazoa - 0; Fungi - 0; Plants - 44;
Viruses - 0; Other Eukaryotes - 114 (source: NCBI BLink).		 0.89 0.32 -0.32
92 AT2G03420 unknown protein; Has 38 Blast hits to 38 proteins in 17
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 38; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 0.89 0.29 -0.31
93 AT4G24770 31-kDa RNA binding protein ARABIDOPSIS THALIANA RNA BINDING
PROTEIN, APPROXIMATELY 31 KD,
ATRBP33, CP31, 31-kDa RNA binding
protein		 0.89 0.31 -0.31
94 AT2G26930 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase 4-(cytidine
5'-phospho)-2-C-methyl-D-erithrito
l kinase, 4-(cytidine
5'-phospho)-2-C-methyl-D-erithrito
l kinase, 4-(cytidine
5′-diphospho)-2-C-methyl-d-e
rythritol kinase, 4-(cytidine
5′-diphospho)-2-C-methyl-d-e
rythritol kinase, ISPE, PIGMENT
DEFECTIVE 277		 0.89 0.31 -0.32
95 AT2G24090 Ribosomal protein L35 0.89 0.32 -0.33
96 AT1G50900 Ankyrin repeat family protein Grana Deficient Chloroplast 1,
LHCP translocation defect		 0.89 0.32 -0.32
97 AT2G42220 Rhodanese/Cell cycle control phosphatase superfamily
protein		 0.89 0.33 -0.31
98 AT5G54600 Translation protein SH3-like family protein 0.89 0.32 -0.31
99 AT3G19810 Protein of unknown function (DUF177) 0.89 0.31 -0.32
100 AT1G22700 Tetratricopeptide repeat (TPR)-like superfamily protein 0.89 0.31 -0.31
101 AT2G37220 RNA-binding (RRM/RBD/RNP motifs) family protein 0.89 0.32 -0.31
102 AT3G23700 Nucleic acid-binding proteins superfamily 0.89 0.3 -0.33
103 AT4G20130 plastid transcriptionally active 14 plastid transcriptionally active
14		 0.89 0.32 -0.31
104 AT2G20890 photosystem II reaction center PSB29 protein photosystem II reaction center
PSB29 protein, THYLAKOID
FORMATION1		 0.89 0.31 -0.32
105 AT2G39670 Radical SAM superfamily protein 0.89 0.32 -0.33
106 AT4G18360 Aldolase-type TIM barrel family protein -0.85 0.32 -0.33
107 AT2G41220 glutamate synthase 2 glutamate synthase 2 -0.84 0.33 -0.31
108 AT3G10500 NAC domain containing protein 53 NAC domain containing protein 53,
NAC domain containing protein 53		 -0.84 0.34 -0.29
109 AT2G41380 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.81 0.32 -0.29
110 AT5G63970 Copine (Calcium-dependent phospholipid-binding protein)
family		 -0.81 0.3 -0.33
111 AT3G25290 Auxin-responsive family protein -0.81 0.32 -0.33
112 AT5G06750 Protein phosphatase 2C family protein -0.8 0.29 -0.29
113 AT2G39350 ABC-2 type transporter family protein ATP-binding cassette G1 -0.8 0.32 -0.32
114 AT1G02850 beta glucosidase 11 beta glucosidase 11 -0.78 0.34 -0.32
115 AT1G76790 O-methyltransferase family protein indole glucosinolate
O-methyltransferase 5		 -0.78 0.31 -0.33
116 AT1G14240 GDA1/CD39 nucleoside phosphatase family protein -0.78 0.31 -0.33
117 AT1G35260 MLP-like protein 165 MLP-like protein 165 -0.78 0.3 -0.33
118 AT5G18270 Arabidopsis NAC domain containing protein 87 Arabidopsis NAC domain containing
protein 87		 -0.78 0.33 -0.31
119 AT2G28110 Exostosin family protein FRAGILE FIBER 8, IRREGULAR XYLEM 7 -0.78 0.32 -0.31
120 AT3G53480 pleiotropic drug resistance 9 ATP-binding cassette G37,
PLEIOTROPIC DRUG RESISTANCE 9,
pleiotropic drug resistance 9,
polar auxin transport inhibitor
sensitive 1		 -0.77 0.3 -0.32
121 AT3G16340 pleiotropic drug resistance 1 ATP-binding cassette G29,
PLEIOTROPIC DRUG RESISTANCE 1,
pleiotropic drug resistance 1		 -0.76 0.32 -0.33
122 AT1G50570 Calcium-dependent lipid-binding (CaLB domain) family
protein		 -0.76 0.31 -0.32
123 AT1G63440 heavy metal atpase 5 heavy metal atpase 5 -0.76 0.34 -0.32
124 AT5G49880 mitotic checkpoint family protein -0.76 0.31 -0.32
125 AT5G18780 F-box/RNI-like superfamily protein -0.75 0.31 -0.32
126 AT4G09030 arabinogalactan protein 10 arabinogalactan protein 10,
ATAGP10		 -0.74 0.33 -0.36
127 AT5G20960 aldehyde oxidase 1 aldehyde oxidase 1, aldehyde
oxidase 1, aldehyde oxidase alpha,
ARABIDOPSIS THALIANA ALDEHYDE
OXIDASE 1, ATAO, Arabidopsis
thaliana aldehyde oxidase 1		 -0.74 0.33 -0.33
128 AT5G49280 hydroxyproline-rich glycoprotein family protein -0.74 0.32 -0.31
129 AT1G05577 Domain of unknown function (DUF966) -0.74 0.33 -0.31
130 AT3G57380 Glycosyltransferase family 61 protein -0.74 0.33 -0.33
131 AT5G37540 Eukaryotic aspartyl protease family protein -0.74 0.29 -0.32
132 AT1G69526 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.74 0.31 -0.33
133 AT3G12760 CONTAINS InterPro DOMAIN/s: Defective-in-cullin neddylation
protein (InterPro:IPR014764), Protein of unknown function
DUF298 (InterPro:IPR005176), UBA-like (InterPro:IPR009060);
BEST Arabidopsis thaliana protein match is: Domain of
unknown function (DUF298) (TAIR:AT1G15860.2); Has 857 Blast
hits to 855 proteins in 202 species: Archae - 0; Bacteria -
0; Metazoa - 482; Fungi - 154; Plants - 139; Viruses - 0;
Other Eukaryotes - 82 (source: NCBI BLink).		 -0.73 0.33 -0.33
134 AT3G61850 Dof-type zinc finger DNA-binding family protein dof affecting germination 1 -0.73 0.32 -0.32
135 AT5G59490 Haloacid dehalogenase-like hydrolase (HAD) superfamily
protein		 -0.73 0.31 -0.31
136 AT5G38030 MATE efflux family protein -0.72 0.32 -0.33
137 AT5G67340 ARM repeat superfamily protein -0.71 0.31 -0.32
138 AT2G46150 Late embryogenesis abundant (LEA) hydroxyproline-rich
glycoprotein family		 -0.71 0.3 -0.29
139 AT3G21770 Peroxidase superfamily protein -0.7 0.33 -0.29
140 AT5G65660 hydroxyproline-rich glycoprotein family protein -0.7 0.33 -0.32
141 AT1G30270 CBL-interacting protein kinase 23 ATCIPK23, CBL-interacting protein
kinase 23, LOW-K+-SENSITIVE 1,
SOS2-like protein kinase 17,
SNF1-RELATED PROTEIN KINASE 3.23		 -0.7 0.34 -0.31
142 AT2G34500 cytochrome P450, family 710, subfamily A, polypeptide 1 cytochrome P450, family 710,
subfamily A, polypeptide 1		 -0.7 0.32 -0.33
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
143 C0051 Aconitic acid cis-Aconitic acid cis-Aconitate glutamine biosynthesis III,
TCA cycle variation V (plant),
glyoxylate cycle,
TCA cycle variation III (eukaryotic) 		-0.75 0.43 -0.46 C0051