AT5G23020 : 2-isopropylmalate synthase 2
Query Information
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AGICode AT5G23020
Description 2-isopropylmalate synthase 2
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT5G23020 2-isopropylmalate synthase 2 2-isopropylmalate synthase 2,
METHYLTHIOALKYMALATE
SYNTHASE-LIKE, MAM3		 1 0.31 -0.29
2 AT3G27190 uridine kinase-like 2 uridine kinase-like 2 0.75 0.31 -0.32
3 AT4G13430 isopropyl malate isomerase large subunit 1 ATLEUC1, isopropyl malate
isomerase large subunit 1		 0.74 0.31 -0.33
4 AT3G13760 Cysteine/Histidine-rich C1 domain family protein 0.73 0.31 -0.34
5 AT1G47270 tubby like protein 6 tubby like protein 6, tubby like
protein 6		 -0.73 0.34 -0.3
6 AT5G06480 Immunoglobulin E-set superfamily protein -0.72 0.31 -0.3
7 AT2G18230 pyrophosphorylase 2 pyrophosphorylase 2,
pyrophosphorylase 2		 -0.72 0.31 -0.33
8 AT1G52050 Mannose-binding lectin superfamily protein 0.72 0.3 -0.33
9 AT1G56170 nuclear factor Y, subunit C2 ATHAP5B, HAP5B, nuclear factor Y,
subunit C2		 -0.71 0.31 -0.32
10 AT5G24930 CONSTANS-like 4 ATCOL4, CONSTANS-like 4 -0.71 0.32 -0.34
11 AT2G39450 Cation efflux family protein ATMTP11, MTP11 -0.71 0.32 -0.31
12 AT5G14640 shaggy-like kinase 13 SHAGGY-LIKE KINASE 13, shaggy-like
kinase 13		 -0.7 0.31 -0.31
13 AT5G42720 Glycosyl hydrolase family 17 protein -0.7 0.31 -0.32
14 AT1G22160 Protein of unknown function (DUF581) -0.7 0.29 -0.3
15 AT5G20990 molybdopterin biosynthesis CNX1 protein / molybdenum
cofactor biosynthesis enzyme CNX1 (CNX1)		 B73, CHLORATE RESISTANT 6,
CO-FACTOR FOR NITRATE REDUCTASE
AND XANTHINE DEHYDROGENASE,
CO-FACTOR FOR NITRATE REDUCTASE
AND XANTHINE DEHYDROGENASE 1,
SIRTINOL 4		 0.7 0.31 -0.3
16 AT5G53130 cyclic nucleotide gated channel 1 CYCLIC NUCLEOTIDE-GATED CHANNEL 1,
cyclic nucleotide gated channel 1		 -0.7 0.33 -0.32
17 AT3G06720 importin alpha isoform 1 IMPORTIN ALPHA, AT-IMP, ATKAP
ALPHA, importin alpha isoform 1,
IMPORTIN ALPHA ISOFORM 1		 0.7 0.33 -0.33
18 AT5G62470 myb domain protein 96 MYB DOMAIN PROTEIN 96, myb domain
protein 96, MYBCOV1		 -0.69 0.31 -0.32
19 AT3G49310 Major facilitator superfamily protein 0.69 0.33 -0.35
20 AT5G65970 Seven transmembrane MLO family protein MILDEW RESISTANCE LOCUS O 10,
MILDEW RESISTANCE LOCUS O 10		 0.69 0.3 -0.32
21 AT1G62710 beta vacuolar processing enzyme beta vacuolar processing enzyme,
BETAVPE		 -0.69 0.33 -0.3
22 AT1G60190 ARM repeat superfamily protein AtPUB19, plant U-box 19 -0.69 0.32 -0.31
23 AT1G56600 galactinol synthase 2 galactinol synthase 2, galactinol
synthase 2		 -0.68 0.32 -0.31
24 AT4G15700 Thioredoxin superfamily protein 0.68 0.34 -0.32
25 AT1G13300 myb-like transcription factor family protein HYPERSENSITIVITY TO LOW
PI-ELICITED PRIMARY ROOT
SHORTENING 1		 0.68 0.29 -0.33
26 AT1G07090 Protein of unknown function (DUF640) LIGHT SENSITIVE HYPOCOTYLS 6 0.68 0.32 -0.32
27 AT3G15780 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G52550.1); Has 20 Blast hits
to 20 proteins in 5 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 20; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.68 0.32 -0.33
28 AT1G16850 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: response to salt stress; LOCATED IN:
endomembrane system; EXPRESSED IN: leaf apex, leaf whorl,
male gametophyte, flower, leaf; EXPRESSED DURING: LP.06 six
leaves visible, LP.04 four leaves visible, LP.10 ten leaves
visible, petal differentiation and expansion stage, LP.08
eight leaves visible; BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT5G64820.1); Has 24 Blast
hits to 24 proteins in 6 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 24; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.68 0.31 -0.31
29 AT1G74090 desulfo-glucosinolate sulfotransferase 18 DESULFO-GLUCOSINOLATE
SULFOTRANSFERASE 18, ARABIDOPSIS
SULFOTRANSFERASE 5B,
desulfo-glucosinolate
sulfotransferase 18		 0.67 0.33 -0.31
30 AT5G08590 SNF1-related protein kinase 2.1 ARABIDOPSIS SERINE/THREONINE
KINASE 2, ARABIDOPSIS SKP1-LIKE1,
SNRK2-1, SNF1-related protein
kinase 2.1, SRK2G		 -0.67 0.3 -0.33
31 AT2G35610 xyloglucanase 113 xyloglucanase 113 0.67 0.31 -0.33
32 AT1G55810 uridine kinase-like 3 uridine kinase-like 3 0.67 0.32 -0.29
33 AT5G47640 nuclear factor Y, subunit B2 nuclear factor Y, subunit B2 -0.67 0.31 -0.31
34 AT5G20270 heptahelical transmembrane protein1 heptahelical transmembrane
protein1		 -0.67 0.29 -0.31
35 AT1G51500 ABC-2 type transporter family protein ATP-binding cassette G12,
AtABCG12, ARABIDOPSIS THALIANA
WHITE-BROWN COMPLEX 12, ECERIFERUM
5, D3, WHITE-BROWN COMPLEX 12		 -0.67 0.29 -0.31
36 AT1G21890 nodulin MtN21 /EamA-like transporter family protein -0.67 0.32 -0.31
37 AT5G10140 K-box region and MADS-box transcription factor family
protein 		AGAMOUS-like 25, FLC, FLOWERING
LOCUS C, FLOWERING LOCUS F		 -0.67 0.32 -0.32
38 AT3G19710 branched-chain aminotransferase4 branched-chain aminotransferase4 0.67 0.3 -0.32
39 AT3G53110 P-loop containing nucleoside triphosphate hydrolases
superfamily protein		 LOW EXPRESSION OF OSMOTICALLY
RESPONSIVE GENES 4		 0.67 0.33 -0.29
40 AT1G69850 nitrate transporter 1:2 nitrate transporter 1:2, nitrate
transporter 1:2, NTL1		 0.67 0.32 -0.32
41 AT5G03690 Aldolase superfamily protein 0.67 0.3 -0.31
42 AT4G22212 Arabidopsis defensin-like protein 0.67 0.32 -0.3
43 AT4G05390 root FNR 1 root FNR 1, root FNR 1 0.66 0.3 -0.34
44 AT1G28230 purine permease 1 ATPUP1, purine permease 1 -0.66 0.3 -0.3
45 AT5G12840 nuclear factor Y, subunit A1 ATHAP2A, EMBRYO DEFECTIVE 2220,
HAP2A, nuclear factor Y, subunit
A1		 -0.66 0.31 -0.31
46 AT2G22240 myo-inositol-1-phosphate synthase 2 INOSITOL 3-PHOSPHATE SYNTHASE 2,
MYO-INOSITOL-1-PHOSTPATE SYNTHASE
2, myo-inositol-1-phosphate
synthase 2		 -0.66 0.31 -0.32
47 AT1G19970 ER lumen protein retaining receptor family protein -0.66 0.3 -0.33
48 AT2G24580 FAD-dependent oxidoreductase family protein 0.66 0.33 -0.31
49 AT1G53080 Legume lectin family protein -0.66 0.31 -0.32
50 AT1G73470 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED
DURING: 13 growth stages; Has 72 Blast hits to 72 proteins
in 35 species: Archae - 0; Bacteria - 50; Metazoa - 0;
Fungi - 0; Plants - 22; Viruses - 0; Other Eukaryotes - 0
(source: NCBI BLink).		 -0.66 0.31 -0.33
51 AT1G58270 TRAF-like family protein ZW9 -0.65 0.33 -0.3
52 AT5G13170 senescence-associated gene 29 AtSWEET15, senescence-associated
gene 29, SWEET15		 -0.65 0.29 -0.32
53 AT1G29160 Dof-type zinc finger DNA-binding family protein 0.65 0.31 -0.32
54 AT2G22490 Cyclin D2;1 ATCYCD2;1, Cyclin D2;1 0.65 0.31 -0.3
55 AT1G77080 K-box region and MADS-box transcription factor family
protein 		AGAMOUS-like 27, FLOWERING LOCUS
M, MADS AFFECTING FLOWERING 1		 -0.65 0.31 -0.3
56 AT2G42540 cold-regulated 15a COR15, cold-regulated 15a -0.65 0.32 -0.31
57 AT3G58990 isopropylmalate isomerase 1 isopropylmalate isomerase 1 0.64 0.31 -0.31
58 AT5G10290 leucine-rich repeat transmembrane protein kinase family
protein		 0.64 0.33 -0.33
59 AT1G02205 Fatty acid hydroxylase superfamily ECERIFERUM 1 -0.64 0.29 -0.31
60 AT5G10210 CONTAINS InterPro DOMAIN/s: C2 calcium-dependent membrane
targeting (InterPro:IPR000008); BEST Arabidopsis thaliana
protein match is: unknown protein (TAIR:AT5G65030.1); Has
1807 Blast hits to 1807 proteins in 277 species: Archae -
0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385;
Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).		 0.64 0.3 -0.3
61 AT4G12460 OSBP(oxysterol binding protein)-related protein 2B OSBP(oxysterol binding
protein)-related protein 2B		 -0.64 0.35 -0.31
62 AT3G22750 Protein kinase superfamily protein 0.64 0.31 -0.32
63 AT5G24620 Pathogenesis-related thaumatin superfamily protein -0.64 0.31 -0.33
64 AT1G09090 respiratory burst oxidase homolog B respiratory burst oxidase homolog
B, ATRBOHB-BETA, respiratory burst
oxidase homolog B		 0.64 0.33 -0.32
65 ATMG00690 hypothetical protein ORF240A 0.64 0.32 -0.31
66 AT4G15680 Thioredoxin superfamily protein 0.63 0.31 -0.32
67 AT3G44840 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 0.62 0.33 -0.32
68 AT5G52310 low-temperature-responsive protein 78 (LTI78) /
desiccation-responsive protein 29A (RD29A)		 COLD REGULATED 78, LTI140,
LOW-TEMPERATURE-INDUCED 78,
RESPONSIVE TO DESSICATION 29A		 -0.62 0.31 -0.31
69 AT5G23750 Remorin family protein -0.62 0.32 -0.32
70 AT5G04310 Pectin lyase-like superfamily protein 0.62 0.31 -0.32
71 AT1G71340 PLC-like phosphodiesterases superfamily protein AtGDPD4, glycerophosphodiester
phosphodiesterase 4		 -0.62 0.33 -0.34
72 AT4G35190 Putative lysine decarboxylase family protein LONELY GUY 5 -0.62 0.32 -0.31
73 AT4G09630 Protein of unknown function (DUF616) 0.62 0.33 -0.31
74 AT5G64080 Bifunctional inhibitor/lipid-transfer protein/seed storage
2S albumin superfamily protein		 AtXYP1, xylogen protein 1 -0.62 0.3 -0.31
75 AT1G71880 sucrose-proton symporter 1 ARABIDOPSIS THALIANA
SUCROSE-PROTON SYMPORTER 1,
sucrose-proton symporter 1		 0.62 0.34 -0.3
76 AT3G02130 receptor-like protein kinase 2 clv3 peptide insensitive 1,
receptor-like protein kinase 2,
TOADSTOOL 2		 -0.62 0.32 -0.31
77 AT1G53640 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: 20 plant structures;
EXPRESSED DURING: 11 growth stages; Has 1186 Blast hits to
678 proteins in 89 species: Archae - 0; Bacteria - 50;
Metazoa - 731; Fungi - 92; Plants - 226; Viruses - 4; Other
Eukaryotes - 83 (source: NCBI BLink).		 0.61 0.3 -0.34
78 AT5G54130 Calcium-binding endonuclease/exonuclease/phosphatase family 0.61 0.31 -0.32
79 AT5G54130 Calcium-binding endonuclease/exonuclease/phosphatase family 0.61 0.33 -0.29
80 AT1G50590 RmlC-like cupins superfamily protein -0.61 0.31 -0.3
81 AT5G25610 BURP domain-containing protein ATRD22, RESPONSIVE TO DESSICATION
22		 -0.61 0.3 -0.32
82 AT4G08480 mitogen-activated protein kinase kinase kinase 9 mitogen-activated protein kinase
kinase kinase 9, MAPK/ERK KINASE
KINASE 2		 -0.61 0.33 -0.32
83 AT5G10620 methyltransferases -0.6 0.33 -0.31
84 AT5G65470 O-fucosyltransferase family protein -0.6 0.3 -0.34
85 AT1G78090 trehalose-6-phosphate phosphatase Arabidopsis thaliana
trehalose-6-phosphate phosphatase
B, trehalose-6-phosphate
phosphatase B		 0.6 0.3 -0.3
86 AT1G06690 NAD(P)-linked oxidoreductase superfamily protein -0.6 0.32 -0.32
87 AT5G14340 myb domain protein 40 myb domain protein 40, myb domain
protein 40		 0.6 0.34 -0.31
88 AT1G78070 Transducin/WD40 repeat-like superfamily protein -0.6 0.32 -0.31
89 AT1G22500 RING/U-box superfamily protein Arabidopsis thaliana Arabidopsis
toxicos en levadura 15,
Arabidopsis toxicos en levadura 15		 0.59 0.3 -0.32
90 AT3G06300 P4H isoform 2 P4H isoform 2, prolyl
4-hydroxylase 2		 0.59 0.31 -0.35
91 AT4G27050 F-box/RNI-like superfamily protein 0.59 0.33 -0.31
92 AT2G03450 purple acid phosphatase 9 PURPLE ACID PHOSPHATASE 9, purple
acid phosphatase 9		 0.59 0.31 -0.31
93 AT1G79970 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED
DURING: 13 growth stages; BEST Arabidopsis thaliana protein
match is: Protein of unknown function (DUF581)
(TAIR:AT2G25690.2); Has 30201 Blast hits to 17322 proteins
in 780 species: Archae - 12; Bacteria - 1396; Metazoa -
17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other
Eukaryotes - 2996 (source: NCBI BLink).		 -0.58 0.31 -0.31
94 AT4G09480 transposable element gene -0.58 0.32 -0.32
95 AT2G04240 RING/U-box superfamily protein XERICO -0.58 0.31 -0.29
96 AT5G01810 CBL-interacting protein kinase 15 PROTEIN KINASE 10, CBL-interacting
protein kinase 15, PKS3,
SOS3-INTERACTING PROTEIN 2,
SNF1-RELATED PROTEIN KINASE 3.1		 -0.58 0.32 -0.31
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
97 C0123 Isoleucine D,L-Isoleucine L-Isoleucine tRNA charging,
isoleucine biosynthesis I (from threonine),
jasmonoyl-amino acid conjugates biosynthesis I,
isoleucine degradation I 		-0.85 0.45 -0.43 C0123
98 C0183 MST_3033.1 - - - -0.79 0.44 -0.45
99 C0252 Threonic acid D,L-Threonic acid L-Threonate ascorbic acid degradation -0.75 0.42 -0.44 C0252
100 C0038 5-(Methylthio)pentylglucosinolate - 5-Methylthiopentylglucosinolate glucosinolate biosynthesis from trihomomethionine -0.68 0.44 -0.42 C0038
101 C0239 Spermidine - Spermidine spermine biosynthesis,
spermine and spermidine degradation III,
beta-alanine biosynthesis I,
hypusine biosynthesis,
spermidine hydroxycinnamic acid conjugates biosynthesis,
spermidine biosynthesis I 		0.65 0.49 -0.42 C0239
102 C0033 4-(Methylsulfinyl)butylglucosinolate - 4-Methylsulfinylbutyl glucosinolate glucosinolate biosynthesis from dihomomethionine -0.65 0.47 -0.5 C0033
103 C0092 Fumaric acid - Fumarate citrulline-nitric oxide cycle,
succinate + a ubiquinone -> a ubiquinol + fumarate,
superpathway of glyoxylate cycle and fatty acid degradation,
tyrosine degradation I,
aerobic respiration (alternative oxidase pathway),
inosine-5'-phosphate biosynthesis II,
arginine biosynthesis I,
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
purine nucleotides de novo biosynthesis II,
arginine biosynthesis II (acetyl cycle),
urea cycle,
aerobic respiration (cytochrome c) 		-0.61 0.32 -0.31 C0092
104 C0219 Pyroglutamic acid (2R,2S)-Pyroglutamic acid 5-Oxoproline gamma-glutamyl cycle (plant pathway),
gamma-glutamyl cycle 		-0.58 0.32 -0.33 C0219