AT3G55160 : -
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AGICode AT3G55160
Description unknown protein; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF2428, death-receptor-like (InterPro:IPR019442); Has 357 Blast hits to 330 proteins in 163 species: Archae - 0; Bacteria - 0; Metazoa - 144; Fungi - 118; Plants - 50; Viruses - 0; Other Eukaryotes - 45 (source: NCBI BLink).
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT3G55160 unknown protein; EXPRESSED IN: 11 plant structures;
EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal
differentiation and expansion stage, E expanded cotyledon
stage, D bilateral stage; CONTAINS InterPro DOMAIN/s:
Protein of unknown function DUF2428, death-receptor-like
(InterPro:IPR019442); Has 357 Blast hits to 330 proteins in
163 species: Archae - 0; Bacteria - 0; Metazoa - 144; Fungi
- 118; Plants - 50; Viruses - 0; Other Eukaryotes - 45
(source: NCBI BLink).
1 0.32 -0.3
2 AT5G12450 FBD-like domain family protein 0.78 0.34 -0.32
3 AT3G46860 Serine protease inhibitor, potato inhibitor I-type family
protein
0.78 0.33 -0.32
4 AT5G52850 Pentatricopeptide repeat (PPR) superfamily protein 0.78 0.32 -0.31
5 AT5G60280 Concanavalin A-like lectin protein kinase family protein 0.77 0.33 -0.33
6 AT4G33450 myb domain protein 69 MYB DOMAIN PROTEIN 69, myb domain
protein 69
0.77 0.31 -0.31
7 ATMG00820 Reverse transcriptase (RNA-dependent DNA polymerase) ORF170 0.75 0.3 -0.3
8 AT4G19370 Protein of unknown function (DUF1218) 0.75 0.31 -0.32
9 AT5G54950 Aconitase family protein 0.75 0.31 -0.31
10 AT3G66656 AGAMOUS-like 91 AGAMOUS-like 91 -0.75 0.33 -0.32
11 AT3G51520 diacylglycerol acyltransferase family -0.74 0.31 -0.31
12 AT4G04480 unknown protein; LOCATED IN: chloroplast; EXPRESSED IN:
flower, pollen tube; EXPRESSED DURING: petal
differentiation and expansion stage; BEST Arabidopsis
thaliana protein match is: F-box family protein with a
domain of unknown function (DUF295) (TAIR:AT4G22030.1); Has
78 Blast hits to 78 proteins in 10 species: Archae - 0;
Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 78; Viruses
- 0; Other Eukaryotes - 0 (source: NCBI BLink).
0.74 0.31 -0.31
13 AT5G24240 Phosphatidylinositol 3- and 4-kinase ;Ubiquitin family
protein
-0.74 0.29 -0.31
14 AT2G15750 transposable element gene 0.74 0.32 -0.3
15 AT3G13170 Spo11/DNA topoisomerase VI, subunit A protein ATSPO11-1 0.74 0.32 -0.32
16 AT5G30480 transposable element gene -0.73 0.32 -0.3
17 AT1G34210 somatic embryogenesis receptor-like kinase 2 ATSERK2, somatic embryogenesis
receptor-like kinase 2
0.73 0.31 -0.28
18 AT4G30590 early nodulin-like protein 12 AtENODL12, early nodulin-like
protein 12
0.73 0.34 -0.29
19 AT5G59590 UDP-glucosyl transferase 76E2 UDP-glucosyl transferase 76E2 0.73 0.33 -0.3
20 AT5G25820 Exostosin family protein 0.73 0.31 -0.32
21 AT2G16760 Calcium-dependent phosphotriesterase superfamily protein 0.73 0.29 -0.33
22 AT1G69990 Leucine-rich repeat protein kinase family protein 0.73 0.31 -0.33
23 AT5G57320 villin, putative villin 5 0.73 0.31 -0.32
24 AT4G29580 Cytidine/deoxycytidylate deaminase family protein 0.73 0.3 -0.3
25 AT2G02515 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: central cell, embryo;
EXPRESSED DURING: C globular stage; Has 18 Blast hits to 17
proteins in 2 species: Archae - 0; Bacteria - 0; Metazoa -
0; Fungi - 0; Plants - 18; Viruses - 0; Other Eukaryotes -
0 (source: NCBI BLink).
0.73 0.35 -0.29
26 AT1G74490 Protein kinase superfamily protein 0.72 0.32 -0.32
27 AT3G42690 transposable element gene 0.72 0.3 -0.32
28 AT5G37590 Tetratricopeptide repeat (TPR)-like superfamily protein 0.72 0.31 -0.31
29 AT4G33870 Peroxidase superfamily protein 0.72 0.32 -0.33
30 AT1G43260 hAT transposon superfamily protein 0.72 0.33 -0.31
31 AT5G06839 bZIP transcription factor family protein bZIP65, TGACG (TGA) motif-binding
protein 10
0.72 0.33 -0.3
32 AT5G64690 neurofilament triplet H protein-related 0.72 0.3 -0.32
33 AT2G37670 Transducin/WD40 repeat-like superfamily protein 0.72 0.33 -0.33
34 AT5G52160 Bifunctional inhibitor/lipid-transfer protein/seed storage
2S albumin superfamily protein
0.71 0.34 -0.34
35 AT1G20550 O-fucosyltransferase family protein 0.71 0.31 -0.29
36 AT5G25160 zinc finger protein 3 zinc finger protein 3 0.71 0.3 -0.32
37 AT3G04420 NAC domain containing protein 48 NAC domain containing protein 48,
NAC domain containing protein 48
0.71 0.32 -0.33
38 AT1G68090 annexin 5 annexin 5, ANNEXIN ARABIDOPSIS
THALIANA 5
0.71 0.32 -0.33
39 AT4G02660 Beige/BEACH domain ;WD domain, G-beta repeat protein 0.71 0.29 -0.3
40 AT2G23800 geranylgeranyl pyrophosphate synthase 2 geranylgeranyl pyrophosphate
synthase 2, GERANYLGERANYL
PYROPHOSPHATE SYNTHASE 5
-0.71 0.31 -0.31
41 AT5G13380 Auxin-responsive GH3 family protein 0.71 0.32 -0.33
42 AT1G59630 F-box associated ubiquitination effector family protein -0.71 0.29 -0.34
43 AT3G01380 transferases;sulfuric ester
hydrolases;catalytics;transferases
0.71 0.32 -0.31
44 AT2G30090 Acyl-CoA N-acyltransferases (NAT) superfamily protein 0.71 0.3 -0.31
45 AT4G20235 cytochrome P450, family 71, subfamily A, polypeptide 28 cytochrome P450, family 71,
subfamily A, polypeptide 28
0.71 0.34 -0.29
46 AT3G18900 FUNCTIONS IN: molecular_function unknown; INVOLVED IN:
biological_process unknown; LOCATED IN: cellular_component
unknown; EXPRESSED IN: synergid; CONTAINS InterPro
DOMAIN/s: F-box associated domain, type 1
(InterPro:IPR006527), F-box associated interaction domain
(InterPro:IPR017451), Protein of unknown function DUF547
(InterPro:IPR006869); BEST Arabidopsis thaliana protein
match is: Protein of unknown function, DUF547
(TAIR:AT5G66600.3).
0.71 0.32 -0.29
47 AT5G34900 transposable element gene 0.71 0.32 -0.29
48 AT1G49150 unknown protein; Has 6 Blast hits to 6 proteins in 2
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 6; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
0.7 0.31 -0.31
49 AT5G22550 Plant protein of unknown function (DUF247) 0.7 0.34 -0.31
50 AT3G58280 Arabidopsis phospholipase-like protein (PEARLI 4) with
TRAF-like domain
0.7 0.32 -0.29
51 AT2G01790 TRAF-like family protein 0.7 0.34 -0.32
52 AT1G28135 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; Has 7 Blast hits to 7 proteins in 1 species:
Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants -
7; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
0.7 0.32 -0.29
53 AT3G22070 proline-rich family protein -0.7 0.32 -0.34
54 AT3G23040 unknown protein; Has 1 Blast hits to 1 proteins in 1
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 1; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
0.7 0.31 -0.32
55 AT2G02380 glutathione S-transferase (class zeta) 2 glutathione S-transferase (class
zeta) 2, glutathione S-transferase
(class zeta) 2
0.7 0.32 -0.33
56 AT4G36105 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
nucleus; EXPRESSED IN: 6 plant structures; EXPRESSED
DURING: LP.04 four leaves visible, 4 anthesis, petal
differentiation and expansion stage; BEST Arabidopsis
thaliana protein match is: unknown protein
(TAIR:AT2G17990.1); Has 30201 Blast hits to 17322 proteins
in 780 species: Archae - 12; Bacteria - 1396; Metazoa -
17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other
Eukaryotes - 2996 (source: NCBI BLink).
0.7 0.29 -0.29
57 AT4G18530 Protein of unknown function (DUF707) -0.7 0.33 -0.31
58 AT1G56690 Pentatricopeptide repeat (PPR) superfamily protein 0.7 0.32 -0.31
59 AT3G51680 NAD(P)-binding Rossmann-fold superfamily protein AtSDR2, short-chain
dehydrogenase/reductase 2
0.69 0.33 -0.32
60 AT5G38340 Disease resistance protein (TIR-NBS-LRR class) family 0.69 0.31 -0.31
61 AT4G13750 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
family protein
EMBRYO DEFECTIVE 2597, NO VEIN 0.69 0.33 -0.31
62 AT5G35140 transposable element gene -0.69 0.32 -0.33
63 AT2G38650 galacturonosyltransferase 7 galacturonosyltransferase 7, LIKE
GLYCOSYL TRANSFERASE 7
0.69 0.34 -0.3
64 AT1G20280 homeobox-leucine zipper protein-related 0.69 0.29 -0.32
65 AT5G43610 sucrose-proton symporter 6 sucrose-proton symporter 6,
sucrose-proton symporter 6
0.69 0.33 -0.34
66 AT2G27380 extensin proline-rich 1 extensin proline-rich 1, extensin
proline-rich 1
0.69 0.31 -0.29
67 AT4G11690 Pentatricopeptide repeat (PPR-like) superfamily protein 0.69 0.35 -0.31
68 AT4G09100 RING/U-box superfamily protein 0.68 0.32 -0.34
69 AT4G32700 helicases;ATP-dependent helicases;nucleic acid binding;ATP
binding;DNA-directed DNA polymerases;DNA binding
TEBICHI 0.68 0.32 -0.34
70 AT3G59490 unknown protein; Has 30 Blast hits to 30 proteins in 12
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 28; Viruses - 0; Other Eukaryotes - 2 (source:
NCBI BLink).
-0.68 0.32 -0.34
71 AT1G36150 Bifunctional inhibitor/lipid-transfer protein/seed storage
2S albumin superfamily protein
0.68 0.34 -0.33
72 AT3G04810 NIMA-related kinase 2 NIMA-related kinase 2,
NIMA-related kinase 2
0.68 0.3 -0.3
73 AT1G34080 transposable element gene 0.68 0.33 -0.32
74 AT5G37620 Cysteine/Histidine-rich C1 domain family protein 0.68 0.31 -0.32
75 AT1G15640 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G15620.1); Has 154 Blast hits
to 146 proteins in 13 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 154; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).
0.68 0.32 -0.34
76 AT2G33460 ROP-interactive CRIB motif-containing protein 1 ROP-interactive CRIB
motif-containing protein 1
0.68 0.31 -0.31
77 AT1G12450 SNARE associated Golgi protein family -0.67 0.29 -0.32
78 AT2G19830 SNF7 family protein SNF7.2, VPS32 -0.67 0.3 -0.32
79 AT2G26630 transposable element gene 0.67 0.32 -0.31
80 AT4G23930 Late embryogenesis abundant (LEA) hydroxyproline-rich
glycoprotein family
-0.67 0.34 -0.31
81 AT1G02540 unknown protein; Has 3327 Blast hits to 2216 proteins in
265 species: Archae - 18; Bacteria - 202; Metazoa - 802;
Fungi - 283; Plants - 84; Viruses - 187; Other Eukaryotes -
1751 (source: NCBI BLink).
0.67 0.32 -0.32
82 AT1G56610 Protein with RNI-like/FBD-like domains -0.67 0.33 -0.34
83 AT1G26760 SET domain protein 35 ATXR1, SET domain protein 35 0.67 0.31 -0.32
84 AT3G32220 transposable element gene -0.67 0.32 -0.3
85 AT3G60760 unknown protein; Has 1 Blast hits to 1 proteins in 1
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 1; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
0.67 0.3 -0.3
86 AT1G32450 nitrate transporter 1.5 nitrate transporter 1.5 0.67 0.32 -0.34
87 AT1G59950 NAD(P)-linked oxidoreductase superfamily protein 0.67 0.31 -0.32
88 AT3G46960 RNA helicase, ATP-dependent, SK12/DOB1 protein 0.67 0.29 -0.3
89 AT4G19440 Tetratricopeptide repeat (TPR)-like superfamily protein 0.66 0.32 -0.31
90 AT3G44980 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT2G07215.1); Has 2 Blast hits to
2 proteins in 1 species: Archae - 0; Bacteria - 0; Metazoa
- 0; Fungi - 0; Plants - 2; Viruses - 0; Other Eukaryotes -
0 (source: NCBI BLink).
-0.66 0.35 -0.33
91 AT3G44210 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT3G43870.1); Has 15 Blast hits
to 15 proteins in 2 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 15; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).
0.66 0.33 -0.29
92 AT2G16970 Major facilitator superfamily protein maternal effect embryo arrest 15 0.66 0.33 -0.28
93 AT2G26390 Serine protease inhibitor (SERPIN) family protein 0.66 0.31 -0.29
94 AT3G42100 transposable element gene 0.66 0.34 -0.31
95 AT4G13820 Leucine-rich repeat (LRR) family protein 0.66 0.33 -0.3
96 AT2G19700 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; Has 5 Blast hits to 5 proteins in 2
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 5; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
-0.66 0.31 -0.34
97 AT1G35380 transposable element gene -0.66 0.33 -0.33
98 AT2G42060 Cysteine/Histidine-rich C1 domain family protein 0.66 0.35 -0.32
99 AT3G43630 Vacuolar iron transporter (VIT) family protein 0.66 0.32 -0.33
100 AT3G42390 unknown protein; Has 1 Blast hits to 1 proteins in 1
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 1; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
-0.65 0.32 -0.33
101 AT1G80420 BRCT domain-containing DNA repair protein ATXRCC1 -0.65 0.3 -0.32
102 AT5G37970 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein
-0.65 0.35 -0.3
103 AT2G15695 Protein of unknown function DUF829, transmembrane 53 -0.65 0.31 -0.31
104 AT1G15590 BEST Arabidopsis thaliana protein match is: RING/U-box
superfamily protein (TAIR:AT1G80400.1); Has 30201 Blast
hits to 17322 proteins in 780 species: Archae - 12;
Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants -
5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI
BLink).
-0.64 0.33 -0.3
105 AT2G15890 maternal effect embryo arrest 14 maternal effect embryo arrest 14 -0.64 0.31 -0.32
106 AT1G26800 RING/U-box superfamily protein -0.64 0.31 -0.31
107 AT2G30650 ATP-dependent caseinolytic (Clp) protease/crotonase family
protein
-0.64 0.31 -0.32
108 AT3G47800 Galactose mutarotase-like superfamily protein -0.63 0.33 -0.32
109 AT2G04000 transposable element gene -0.63 0.32 -0.32
110 AT2G24010 serine carboxypeptidase-like 23 serine carboxypeptidase-like 23 -0.63 0.31 -0.3
111 AT4G18850 unknown protein; Has 6 Blast hits to 6 proteins in 2
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 6; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
-0.63 0.33 -0.32
112 AT2G36090 F-box family protein -0.63 0.31 -0.29
113 AT3G48880 RNI-like superfamily protein -0.63 0.32 -0.3
114 AT2G30430 unknown protein; Has 3 Blast hits to 3 proteins in 1
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 3; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
-0.63 0.32 -0.31
115 AT5G39860 basic helix-loop-helix (bHLH) DNA-binding family protein BASIC HELIX-LOOP-HELIX PROTEIN
136, BANQUO 1, PACLOBUTRAZOL
RESISTANCE1
-0.63 0.31 -0.32
116 AT2G43270 F-box and associated interaction domains-containing protein -0.63 0.3 -0.33
117 AT4G34500 Protein kinase superfamily protein -0.62 0.32 -0.33
118 AT1G69010 BES1-interacting Myc-like protein 2 BES1-interacting Myc-like protein
2
-0.62 0.3 -0.34
119 AT3G04280 response regulator 22 response regulator 22, response
regulator 22
-0.62 0.32 -0.34
120 AT1G54140 TATA binding protein associated factor 21kDa subunit TBP-ASSOCIATED FACTOR 9, TATA
binding protein associated factor
21kDa subunit
-0.62 0.31 -0.31
121 AT3G28490 Oxoglutarate/iron-dependent oxygenase -0.62 0.29 -0.31
122 AT5G13790 AGAMOUS-like 15 AGAMOUS-like 15 -0.62 0.31 -0.32
123 AT5G03260 laccase 11 laccase 11 -0.62 0.31 -0.31
124 AT1G49100 Leucine-rich repeat protein kinase family protein -0.61 0.32 -0.34
125 AT2G23900 Pectin lyase-like superfamily protein -0.61 0.31 -0.32
126 AT3G62230 F-box family protein DUO1-activated F-box 1 -0.61 0.32 -0.33
127 AT4G04560 transposable element gene -0.61 0.32 -0.31
128 AT2G24950 Protein of Unknown Function (DUF239) -0.61 0.31 -0.31
129 AT1G21010 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: N-terminal protein myristoylation; LOCATED IN:
cellular_component unknown; EXPRESSED IN: 24 plant
structures; EXPRESSED DURING: 14 growth stages; BEST
Arabidopsis thaliana protein match is: unknown protein
(TAIR:AT1G76600.1); Has 206 Blast hits to 206 proteins in
13 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi -
0; Plants - 206; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).
-0.61 0.34 -0.33
130 AT4G13640 Homeodomain-like superfamily protein unfertilized embryo sac 16 -0.61 0.32 -0.31
131 AT2G47560 RING/U-box superfamily protein -0.61 0.32 -0.32
132 AT5G42560 Abscisic acid-responsive (TB2/DP1, HVA22) family protein -0.61 0.32 -0.32
133 AT1G72960 Root hair defective 3 GTP-binding protein (RHD3) -0.6 0.32 -0.33
134 AT1G67890 PAS domain-containing protein tyrosine kinase family
protein
-0.6 0.31 -0.31
135 AT2G29700 pleckstrin homologue 1 pleckstrin homologue 1, pleckstrin
homologue 1
-0.6 0.31 -0.32
136 AT3G42860 zinc knuckle (CCHC-type) family protein -0.6 0.32 -0.33
137 AT5G14890 NHL domain-containing protein -0.6 0.31 -0.29
138 AT5G56320 expansin A14 ATEXP14, expansin A14, ATHEXP
ALPHA 1.5, EXPANSIN 14, expansin
A14
-0.6 0.33 -0.32
139 AT3G16730 CONTAINS InterPro DOMAIN/s: Non-SMC condensin II complex,
subunit H2-like (InterPro:IPR009378); Has 249 Blast hits to
211 proteins in 82 species: Archae - 0; Bacteria - 0;
Metazoa - 145; Fungi - 8; Plants - 30; Viruses - 0; Other
Eukaryotes - 66 (source: NCBI BLink).
hypersensitive to excess boron 2 -0.6 0.32 -0.34
140 AT1G05990 EF hand calcium-binding protein family ROOT HAIR SPECIFIC 1 -0.59 0.32 -0.33
141 AT1G78500 Terpenoid cyclases family protein -0.59 0.31 -0.32
142 AT5G58003 C-terminal domain phosphatase-like 4 C-terminal domain phosphatase-like
4
-0.59 0.33 -0.31
143 AT1G05330 unknown protein; Has 6 Blast hits to 6 proteins in 2
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 6; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).
-0.59 0.35 -0.35
144 AT5G09950 Tetratricopeptide repeat (TPR)-like superfamily protein -0.59 0.32 -0.29
145 AT1G55660 FBD, F-box and Leucine Rich Repeat domains containing
protein
-0.59 0.32 -0.34
146 AT2G21240 basic pentacysteine 4 BASIC PENTACYSTEINE 4, BBR, basic
pentacysteine 4
-0.59 0.32 -0.32
147 AT1G65810 P-loop containing nucleoside triphosphate hydrolases
superfamily protein
-0.59 0.3 -0.33
148 AT4G40040 Histone superfamily protein -0.59 0.32 -0.31
149 AT1G69780 Homeobox-leucine zipper protein family ATHB13 -0.59 0.31 -0.32
150 AT4G29200 Beta-galactosidase related protein -0.59 0.33 -0.34
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
151 C0178 MST_2446.7 - - - -0.69 0.46 -0.45