AT3G05150 : -
Query Information
Cytoscape Web will replace the contents of this div with your graph.
AGICode AT3G05150
Description Major facilitator superfamily protein
Gene information
Help   
  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT3G05150 Major facilitator superfamily protein 1 0.32 -0.31
2 AT5G15350 early nodulin-like protein 17 AtENODL17, early nodulin-like
protein 17		 0.84 0.3 -0.32
3 AT3G48750 cell division control 2 cell division control 2, CDC2A,
CDC2AAT, CDK2, CDKA1, CDKA;1		 0.82 0.3 -0.31
4 AT5G62490 HVA22 homologue B ARABIDOPSIS THALIANA HVA22
HOMOLOGUE B, HVA22 homologue B		 -0.8 0.34 -0.3
5 AT2G30050 transducin family protein / WD-40 repeat family protein 0.8 0.32 -0.31
6 AT2G32270 zinc transporter 3 precursor zinc transporter 3 precursor 0.79 0.33 -0.32
7 AT5G39320 UDP-glucose 6-dehydrogenase family protein 0.78 0.32 -0.33
8 AT4G03200 catalytics -0.78 0.31 -0.33
9 AT5G01300 PEBP (phosphatidylethanolamine-binding protein) family
protein		 -0.77 0.34 -0.32
10 AT4G32840 phosphofructokinase 6 phosphofructokinase 6 0.77 0.33 -0.32
11 AT2G43600 Chitinase family protein 0.77 0.31 -0.32
12 AT5G52300 CAP160 protein LOW-TEMPERATURE-INDUCED 65,
RESPONSIVE TO DESSICATION 29B		 -0.77 0.31 -0.31
13 AT3G50380 Protein of unknown function (DUF1162) -0.76 0.31 -0.29
14 AT5G51490 Plant invertase/pectin methylesterase inhibitor superfamily 0.76 0.33 -0.3
15 AT1G03870 FASCICLIN-like arabinoogalactan 9 FASCICLIN-like arabinoogalactan 9 0.76 0.32 -0.34
16 AT5G57610 Protein kinase superfamily protein with
octicosapeptide/Phox/Bem1p domain		 -0.76 0.3 -0.32
17 AT5G56280 COP9 signalosome subunit 6A COP9 signalosome subunit 6A 0.76 0.31 -0.33
18 AT4G17460 Homeobox-leucine zipper protein 4 (HB-4) / HD-ZIP protein HAT1 0.76 0.33 -0.32
19 AT2G18440 GUT15 (GENE WITH UNSTABLE TRANSCRIPT 15); other RNA GENE WITH UNSTABLE TRANSCRIPT 15 -0.75 0.31 -0.31
20 AT4G19390 Uncharacterised protein family (UPF0114) -0.75 0.3 -0.32
21 AT4G34960 Cyclophilin-like peptidyl-prolyl cis-trans isomerase family
protein		 0.75 0.32 -0.31
22 AT1G52060 Mannose-binding lectin superfamily protein 0.75 0.32 -0.31
23 AT2G19900 NADP-malic enzyme 1 Arabidopsis thaliana NADP-malic
enzyme 1, NADP-malic enzyme 1		 -0.75 0.32 -0.33
24 AT5G05440 Polyketide cyclase/dehydrase and lipid transport
superfamily protein		 PYRABACTIN RESISTANCE 1-LIKE 5,
regulatory component of ABA
receptor 8		 0.75 0.32 -0.31
25 AT5G62090 SEUSS-like 2 SEUSS-like 2 -0.75 0.3 -0.32
26 AT2G19760 profilin 1 PROFILIN 1, profilin 1 0.75 0.32 -0.33
27 AT3G05030 sodium hydrogen exchanger 2 ATNHX2, sodium hydrogen exchanger
2		 -0.74 0.32 -0.31
28 AT1G63220 Calcium-dependent lipid-binding (CaLB domain) family
protein		 0.74 0.33 -0.32
29 AT2G21590 Glucose-1-phosphate adenylyltransferase family protein APL4 -0.74 0.3 -0.32
30 AT3G22380 time for coffee TIME FOR COFFEE -0.74 0.31 -0.31
31 AT4G15700 Thioredoxin superfamily protein 0.74 0.32 -0.3
32 AT2G38310 PYR1-like 4 PYR1-like 4, regulatory components
of ABA receptor 10		 0.74 0.31 -0.32
33 AT4G35200 Arabidopsis protein of unknown function (DUF241) 0.74 0.32 -0.33
34 AT4G17190 farnesyl diphosphate synthase 2 farnesyl diphosphate synthase 2 0.74 0.3 -0.33
35 AT3G47080 Tetratricopeptide repeat (TPR)-like superfamily protein -0.74 0.31 -0.31
36 AT2G41210 phosphatidylinositol- 4-phosphate 5-kinase 5 phosphatidylinositol- 4-phosphate
5-kinase 5		 -0.73 0.32 -0.31
37 AT2G37700 Fatty acid hydroxylase superfamily 0.73 0.3 -0.32
38 AT1G27310 nuclear transport factor 2A nuclear transport factor 2A 0.73 0.32 -0.32
39 AT1G49240 actin 8 actin 8, FRIZZY AND KINKED SHOOTS 0.73 0.32 -0.32
40 AT2G22475 GRAM domain family protein GL2-EXPRESSION MODULATOR 0.73 0.33 -0.32
41 AT5G23670 long chain base2 long chain base2 0.73 0.32 -0.29
42 AT3G61890 homeobox 12 homeobox 12, ARABIDOPSIS THALIANA
HOMEOBOX 12, homeobox 12		 -0.73 0.3 -0.3
43 AT1G32460 unknown protein; Has 19 Blast hits to 19 proteins in 8
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 19; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 0.73 0.32 -0.32
44 AT1G79520 Cation efflux family protein -0.73 0.32 -0.32
45 AT5G15190 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED
DURING: LP.04 four leaves visible, 4 anthesis, petal
differentiation and expansion stage, E expanded cotyledon
stage, D bilateral stage; Has 7 Blast hits to 7 proteins in
3 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi -
0; Plants - 7; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 -0.73 0.34 -0.33
46 AT2G36390 starch branching enzyme 2.1 BRANCHING ENZYME 3, starch
branching enzyme 2.1		 -0.73 0.32 -0.32
47 AT2G41190 Transmembrane amino acid transporter family protein -0.73 0.31 -0.32
48 AT5G26570 catalytics;carbohydrate kinases;phosphoglucan, water
dikinases		 ATGWD3, OK1, PHOSPHOGLUCAN WATER
DIKINASE		 -0.73 0.31 -0.3
49 AT1G70990 proline-rich family protein 0.73 0.29 -0.3
50 AT3G06510 Glycosyl hydrolase superfamily protein SENSITIVE TO FREEZING 2, SENSITIVE
TO FREEZING 2		 -0.72 0.3 -0.32
51 AT3G14850 TRICHOME BIREFRINGENCE-LIKE 41 TRICHOME BIREFRINGENCE-LIKE 41 0.72 0.31 -0.32
52 AT3G24190 Protein kinase superfamily protein -0.72 0.29 -0.32
53 AT2G30060 Pleckstrin homology (PH) domain superfamily protein 0.72 0.33 -0.32
54 AT5G06740 Concanavalin A-like lectin protein kinase family protein 0.72 0.3 -0.32
55 AT4G14000 Putative methyltransferase family protein 0.71 0.31 -0.32
56 AT4G15690 Thioredoxin superfamily protein 0.71 0.31 -0.31
57 AT5G22290 NAC domain containing protein 89 NAC domain containing protein 89,
fructose-sensing quantitative
trait locus 6, NAC domain
containing protein 89		 -0.71 0.32 -0.31
58 AT4G21940 calcium-dependent protein kinase 15 calcium-dependent protein kinase
15		 -0.71 0.32 -0.33
59 AT1G68570 Major facilitator superfamily protein -0.71 0.32 -0.3
60 AT1G54890 Late embryogenesis abundant (LEA) protein-related 0.71 0.31 -0.32
61 AT1G67310 Calmodulin-binding transcription activator protein with
CG-1 and Ankyrin domains		 -0.71 0.32 -0.34
62 AT5G47770 farnesyl diphosphate synthase 1 farnesyl diphosphate synthase 1 0.71 0.31 -0.29
63 AT3G19710 branched-chain aminotransferase4 branched-chain aminotransferase4 0.71 0.31 -0.33
64 AT3G24670 Pectin lyase-like superfamily protein 0.7 0.31 -0.31
65 AT5G25560 CHY-type/CTCHY-type/RING-type Zinc finger protein -0.7 0.31 -0.31
66 AT3G55730 myb domain protein 109 myb domain protein 109, myb domain
protein 109		 0.7 0.32 -0.33
67 AT5G07050 nodulin MtN21 /EamA-like transporter family protein -0.7 0.31 -0.3
68 AT2G38905 Low temperature and salt responsive protein family -0.7 0.31 -0.32
69 AT5G50375 cyclopropyl isomerase cyclopropyl isomerase 0.7 0.33 -0.32
70 AT1G11740 ankyrin repeat family protein 0.7 0.32 -0.3
71 AT3G04240 Tetratricopeptide repeat (TPR)-like superfamily protein secret agent -0.7 0.33 -0.33
72 AT4G22720 Actin-like ATPase superfamily protein 0.7 0.31 -0.3
73 AT1G72430 SAUR-like auxin-responsive protein family 0.7 0.33 -0.32
74 AT1G35580 cytosolic invertase 1 alkaline/neutral invertase G,
cytosolic invertase 1		 0.7 0.3 -0.29
75 AT5G12140 cystatin-1 cystatin-1, cystatin-1 -0.69 0.32 -0.32
76 AT5G53250 arabinogalactan protein 22 arabinogalactan protein 22,
ARABINOGALACTAN PROTEIN 22		 0.69 0.31 -0.33
77 AT1G10570 Cysteine proteinases superfamily protein OVERLY TOLERANT TO SALT 2, UB-LIKE
PROTEASE 1C		 -0.69 0.31 -0.29
78 AT3G54920 Pectin lyase-like superfamily protein powdery mildew resistant 6 0.69 0.31 -0.31
79 AT2G21820 unknown protein; Has 45 Blast hits to 45 proteins in 13
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 45; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 -0.69 0.32 -0.3
80 AT1G24706 THO2 AtTHO2, EMBRYO DEFECTIVE 2793,
THO2		 -0.69 0.31 -0.3
81 AT4G35300 tonoplast monosaccharide transporter2 tonoplast monosaccharide
transporter2		 -0.69 0.31 -0.33
82 AT4G17870 Polyketide cyclase/dehydrase and lipid transport
superfamily protein		 PYRABACTIN RESISTANCE 1,
regulatory component of ABA
receptor 11		 0.69 0.31 -0.33
83 AT5G63400 adenylate kinase 1 adenylate kinase 1 0.69 0.31 -0.33
84 AT3G08020 PHD finger family protein -0.69 0.33 -0.32
85 ATCG01100 NADH dehydrogenase family protein NDHA -0.68 0.31 -0.32
86 AT1G52070 Mannose-binding lectin superfamily protein 0.68 0.3 -0.32
87 AT2G15810 transposable element gene -0.68 0.3 -0.32
88 AT5G11060 KNOTTED1-like homeobox gene 4 KNOTTED1-like homeobox gene 4 -0.68 0.33 -0.32
89 AT1G77800 PHD finger family protein -0.68 0.32 -0.31
90 AT1G14040 EXS (ERD1/XPR1/SYG1) family protein 0.68 0.33 -0.31
91 AT3G58990 isopropylmalate isomerase 1 isopropylmalate isomerase 1 0.68 0.33 -0.32
92 AT5G55390 ENHANCED DOWNY MILDEW 2 ENHANCED DOWNY MILDEW 2 -0.68 0.34 -0.29
93 ATCG00530 CemA-like proton extrusion protein-related YCF10 -0.68 0.3 -0.33
94 AT2G38700 mevalonate diphosphate decarboxylase 1 ATMVD1, mevalonate diphosphate
decarboxylase 1		 0.68 0.33 -0.32
95 AT1G73250 GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1 ACTIVATING TRANSCRIPTION FACTOR 5,
GDP-4-keto-6-deoxymannose-3,5-epim
erase-4-reductase 1		 0.68 0.32 -0.3
96 AT2G43500 Plant regulator RWP-RK family protein -0.68 0.32 -0.34
97 AT5G01520 RING/U-box superfamily protein ABA Insensitive RING Protein 2,
AtAIRP2		 -0.68 0.32 -0.32
98 AT4G15680 Thioredoxin superfamily protein 0.68 0.32 -0.31
99 AT1G18580 galacturonosyltransferase 11 galacturonosyltransferase 11 0.68 0.3 -0.34
100 AT5G56520 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G55365.1); Has 30201 Blast
hits to 17322 proteins in 780 species: Archae - 12;
Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants -
5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI
BLink).		 -0.68 0.32 -0.29
101 AT3G07070 Protein kinase superfamily protein 0.68 0.32 -0.32
102 AT4G14760 kinase interacting (KIP1-like) family protein -0.68 0.31 -0.31
103 AT2G37130 Peroxidase superfamily protein 0.67 0.33 -0.34
104 AT2G43880 Pectin lyase-like superfamily protein 0.67 0.3 -0.31
105 AT3G04780 Protein of unknown function (DUF1000) 0.67 0.32 -0.33
106 AT5G13870 xyloglucan endotransglucosylase/hydrolase 5 endoxyloglucan transferase A4,
xyloglucan
endotransglucosylase/hydrolase 5		 0.67 0.31 -0.33
107 AT5G45610 protein dimerizations SENSITIVE TO UV 2 -0.67 0.32 -0.33
108 AT3G47980 Integral membrane HPP family protein 0.67 0.32 -0.33
109 ATCG00080 photosystem II reaction center protein I photosystem II reaction center
protein I		 -0.67 0.3 -0.32
110 AT4G34215 Domain of unknown function (DUF303) 0.67 0.32 -0.3
111 AT5G20840 Phosphoinositide phosphatase family protein -0.67 0.31 -0.33
112 AT1G70900 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G23110.4); Has 57 Blast hits
to 57 proteins in 14 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 57; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.67 0.31 -0.32
113 AT1G10760 Pyruvate phosphate dikinase, PEP/pyruvate binding domain GWD, GWD1, STARCH EXCESS 1, SOP,
SOP1		 -0.67 0.33 -0.31
114 AT2G21045 Rhodanese/Cell cycle control phosphatase superfamily
protein		 0.67 0.31 -0.33
115 AT3G09300 OSBP(oxysterol binding protein)-related protein 3B OSBP(oxysterol binding
protein)-related protein 3B		 0.67 0.3 -0.3
116 AT4G15660 Thioredoxin superfamily protein 0.67 0.32 -0.33
117 AT3G16360 HPT phosphotransmitter 4 HPT phosphotransmitter 4 -0.67 0.32 -0.31
118 AT2G37120 S1FA-like DNA-binding protein 0.66 0.32 -0.31
119 AT1G16030 heat shock protein 70B heat shock protein 70B -0.66 0.32 -0.31
120 AT1G21160 eukaryotic translation initiation factor 2 (eIF-2) family
protein		 -0.66 0.32 -0.31
121 AT5G60660 plasma membrane intrinsic protein 2;4 plasma membrane intrinsic protein
2;4, PIP2F		 0.66 0.32 -0.32
122 AT5G24410 6-phosphogluconolactonase 4 6-phosphogluconolactonase 4 0.66 0.35 -0.32
123 AT5G10430 arabinogalactan protein 4 arabinogalactan protein 4, ATAGP4 0.66 0.3 -0.3
124 AT5G05610 alfin-like 1 alfin-like 1 0.66 0.31 -0.33
125 AT3G55460 SC35-like splicing factor 30 SC35-like splicing factor 30,
SC35-like splicing factor 30		 0.66 0.33 -0.3
126 AT4G26550 Got1/Sft2-like vescicle transport protein family 0.66 0.33 -0.34
127 AT5G07960 unknown protein; CONTAINS InterPro DOMAIN/s:
Uncharacterised protein family UPF0139
(InterPro:IPR005351); Has 193 Blast hits to 193 proteins in
75 species: Archae - 0; Bacteria - 0; Metazoa - 130; Fungi
- 0; Plants - 52; Viruses - 0; Other Eukaryotes - 11
(source: NCBI BLink).		 0.66 0.33 -0.31
128 AT3G19960 myosin 1 myosin 1 -0.66 0.32 -0.31
129 AT1G28230 purine permease 1 ATPUP1, purine permease 1 -0.66 0.34 -0.33
130 AT4G03190 GRR1-like protein 1 AUXIN SIGNALING F BOX PROTEIN 1,
ATGRH1, GRR1-like protein 1		 0.66 0.33 -0.34
131 AT1G17870 ethylene-dependent gravitropism-deficient and
yellow-green-like 3		 ETHYLENE-DEPENDENT
GRAVITROPISM-DEFICIENT AND
YELLOW-GREEN-LIKE 3,
ETHYLENE-DEPENDENT
GRAVITROPISM-DEFICIENT AND
YELLOW-GREEN-LIKE 3		 -0.66 0.31 -0.3
132 AT1G71860 protein tyrosine phosphatase 1 ATPTP1, protein tyrosine
phosphatase 1		 0.66 0.31 -0.3
133 AT5G14070 Thioredoxin superfamily protein ROXY2 0.66 0.32 -0.32
134 ATCG00590 electron carriers ORF31 -0.66 0.33 -0.31
135 AT1G56680 Chitinase family protein 0.66 0.32 -0.31
136 AT1G67110 cytochrome P450, family 735, subfamily A, polypeptide 2 cytochrome P450, family 735,
subfamily A, polypeptide 2		 0.66 0.31 -0.29
137 AT3G56080 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.65 0.34 -0.31
138 AT2G25890 Oleosin family protein -0.65 0.32 -0.31
139 AT1G13920 Remorin family protein -0.65 0.31 -0.32
140 AT5G35180 Protein of unknown function (DUF1336) -0.65 0.32 -0.31
141 AT3G26350 LOCATED IN: chloroplast; EXPRESSED IN: root, pedicel,
carpel, stamen; EXPRESSED DURING: 4 anthesis, petal
differentiation and expansion stage; CONTAINS InterPro
DOMAIN/s: Late embryogenesis abundant protein, group 2
(InterPro:IPR004864); BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT1G13050.1); Has 3534
Blast hits to 2704 proteins in 342 species: Archae - 6;
Bacteria - 192; Metazoa - 1076; Fungi - 505; Plants - 1162;
Viruses - 224; Other Eukaryotes - 369 (source: NCBI BLink).		 -0.65 0.32 -0.31
142 AT4G16160 Mitochondrial import inner membrane translocase subunit
Tim17/Tim22/Tim23 family protein		 ATOEP16-2, ATOEP16-S -0.64 0.32 -0.31
143 AT4G09020 isoamylase 3 ATISA3, isoamylase 3 -0.64 0.32 -0.33
144 AT2G46180 golgin candidate 4 golgin candidate 4 -0.64 0.31 -0.33
145 AT5G06530 ABC-2 type transporter family protein ATP-binding cassette G22,
Arabidopsis thaliana ATP-binding
cassette G22		 -0.64 0.31 -0.34
146 AT5G58160 actin binding -0.64 0.3 -0.33
147 AT1G20100 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT1G75860.1); Has 471 Blast hits
to 438 proteins in 92 species: Archae - 0; Bacteria - 14;
Metazoa - 217; Fungi - 43; Plants - 91; Viruses - 1; Other
Eukaryotes - 105 (source: NCBI BLink).		 -0.64 0.31 -0.32
148 AT3G23340 casein kinase I-like 10 casein kinase I-like 10 -0.64 0.3 -0.29
149 ATCG01090 NADPH dehydrogenases NDHI -0.64 0.32 -0.3
150 AT2G43800 Actin-binding FH2 (formin homology 2) family protein -0.64 0.34 -0.31
151 AT4G18810 NAD(P)-binding Rossmann-fold superfamily protein -0.64 0.31 -0.32
152 AT3G15350 Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase
family protein		 -0.63 0.29 -0.32
153 AT1G23200 Plant invertase/pectin methylesterase inhibitor superfamily -0.63 0.33 -0.3
154 AT1G62710 beta vacuolar processing enzyme beta vacuolar processing enzyme,
BETAVPE		 -0.63 0.32 -0.29
155 ATCG00120 ATP synthase subunit alpha ATP synthase subunit alpha -0.63 0.33 -0.32
156 AT5G47020 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: 23 plant structures;
EXPRESSED DURING: 13 growth stages; BEST Arabidopsis
thaliana protein match is: unknown protein
(TAIR:AT5G11700.2); Has 1807 Blast hits to 1807 proteins in
277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi
- 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339
(source: NCBI BLink).		 -0.63 0.32 -0.34
157 AT1G01830 ARM repeat superfamily protein -0.63 0.34 -0.32
158 AT1G36160 acetyl-CoA carboxylase 1 acetyl-CoA carboxylase 1, AT-ACC1,
EMBRYO DEFECTIVE 22, GURKE,
GLOSSYHEAD 1, PASTICCINO 3		 -0.63 0.31 -0.31
159 AT5G58870 FTSH protease 9 FTSH protease 9 -0.63 0.32 -0.31
160 AT2G29190 pumilio 2 pumilio 2, pumilio 2 -0.63 0.31 -0.32
161 AT3G60240 eukaryotic translation initiation factor 4G CUCUMOVIRUS MULTIPLICATION 2,
eukaryotic translation initiation
factor 4G		 -0.63 0.31 -0.33
162 AT1G24735 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.63 0.33 -0.33
163 AT3G59770 sacI homology domain-containing protein / WW
domain-containing protein		 ARABIDOPSIS THALIANA SUPPRESSOR OF
ACTIN 9, SUPPRESSOR OF ACTIN 9		 -0.63 0.3 -0.3
164 AT4G35190 Putative lysine decarboxylase family protein LONELY GUY 5 -0.63 0.31 -0.33
165 AT5G35260 transposable element gene -0.63 0.32 -0.33
Metabolite information
Help   
  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
166 C0136 Lactic acid D,L-Lactic acid Lactate pyruvate fermentation to lactate 0.77 0.49 -0.43 C0136
167 C0193 Pantothenic acid D,L-Pantothenic acid Pantothenate pantothenate biosynthesis -0.71 0.46 -0.44 C0193
168 C0131 Kaempferol-3-O-β-glucopyranoside-7-O-α-rhamnopyranoside Kaempferol-3-O-β-D-glucopyranoside-7-O-α-L-rhamnopyranoside Kaempferol-3-glucoside-7-rhamnoside kaempferol glucoside biosynthesis (Arabidopsis) -0.7 0.46 -0.44 C0131