C0219 : Pyroglutamic acid
Query Information
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ID C0219
Compound name Pyroglutamic acid
External link   http://pmn.plantcyc.org/ARA/NEW-IMAGE?type=COMPOUND&object=5-OXOPROLINE
Pathway Information gamma-glutamyl cycle (plant pathway),
gamma-glutamyl cycle
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT4G35500 Protein kinase superfamily protein -0.68 0.32 -0.3
2 AT1G61940 tubby like protein 4 tubby like protein 4, tubby like
protein 4		 -0.62 0.3 -0.3
3 AT1G71880 sucrose-proton symporter 1 ARABIDOPSIS THALIANA
SUCROSE-PROTON SYMPORTER 1,
sucrose-proton symporter 1		 -0.61 0.31 -0.31
4 AT1G17720 Protein phosphatase 2A, regulatory subunit PR55 ATB BETA -0.59 0.31 -0.31
5 AT3G45480 RING/U-box protein with C6HC-type zinc finger 0.58 0.3 -0.32
6 AT5G23020 2-isopropylmalate synthase 2 2-isopropylmalate synthase 2,
METHYLTHIOALKYMALATE
SYNTHASE-LIKE, MAM3		 -0.58 0.31 -0.31
7 AT5G61960 MEI2-like protein 1 MEI2-like protein 1, MEI2-like
protein 1		 -0.58 0.3 -0.32
8 AT1G47270 tubby like protein 6 tubby like protein 6, tubby like
protein 6		 0.58 0.31 -0.3
9 AT2G42240 RNA-binding (RRM/RBD/RNP motifs) family protein 0.58 0.32 -0.31
10 AT3G57860 UV-B-insensitive 4-like GIGAS CELL 1, OMISSION OF SECOND
DIVISION, UV-B-insensitive 4-like		 0.57 0.33 -0.31
11 AT5G57260 cytochrome P450, family 71, subfamily B, polypeptide 10 cytochrome P450, family 71,
subfamily B, polypeptide 10		 0.56 0.31 -0.34
12 AT5G28590 DNA-binding family protein -0.56 0.31 -0.3
13 AT3G15490 Regulator of Vps4 activity in the MVB pathway protein -0.55 0.3 -0.34
14 AT2G31440 INVOLVED IN: positive regulation of catalytic activity,
protein processing; LOCATED IN: integral to membrane;
EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15
growth stages; CONTAINS InterPro DOMAIN/s: Aph-1
(InterPro:IPR009294); Has 268 Blast hits to 262 proteins in
79 species: Archae - 0; Bacteria - 0; Metazoa - 212; Fungi
- 0; Plants - 34; Viruses - 0; Other Eukaryotes - 22
(source: NCBI BLink).		 0.55 0.31 -0.3
15 AT5G08100 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
superfamily protein		 asparaginase A1 0.55 0.31 -0.32
16 AT5G50410 unknown protein; Has 1807 Blast hits to 1807 proteins in
277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi
- 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339
(source: NCBI BLink).		 0.55 0.3 -0.33
17 AT5G54830 DOMON domain-containing protein / dopamine
beta-monooxygenase N-terminal domain-containing protein		 -0.55 0.31 -0.31
18 AT3G18770 Autophagy-related protein 13 -0.54 0.31 -0.31
19 AT1G68510 LOB domain-containing protein 42 LOB domain-containing protein 42 -0.54 0.31 -0.3
20 AT1G66030 cytochrome P450, family 96, subfamily A, polypeptide 14
pseudogene		 cytochrome P450, family 96,
subfamily A, polypeptide 14
pseudogene		 -0.53 0.3 -0.31
21 AT2G32440 ent-kaurenoic acid hydroxylase 2 ARABIDOPSIS ENT-KAURENOIC ACID
HYDROXYLASE 2, CYP88A4,
ent-kaurenoic acid hydroxylase 2		 0.53 0.31 -0.32
22 AT5G01720 RNI-like superfamily protein -0.53 0.32 -0.32
23 AT2G29800 Galactose oxidase/kelch repeat superfamily protein -0.52 0.32 -0.3
24 AT3G13140 hydroxyproline-rich glycoprotein family protein 0.52 0.29 -0.31
25 AT4G14290 alpha/beta-Hydrolases superfamily protein 0.52 0.31 -0.33
26 AT5G41790 COP1-interactive protein 1 COP1-interactive protein 1 -0.51 0.34 -0.32
27 AT3G44140 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: sperm cell, male
gametophyte, pollen tube; EXPRESSED DURING: M germinated
pollen stage; Has 1 Blast hits to 1 proteins in 1 species:
Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants -
1; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).		 -0.51 0.31 -0.33
28 AT2G26320 AGAMOUS-like 33 AGAMOUS-like 33 0.51 0.31 -0.3
29 AT3G43110 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: petal, flower; EXPRESSED
DURING: 4 anthesis, petal differentiation and expansion
stage; BEST Arabidopsis thaliana protein match is: unknown
protein (TAIR:AT5G20790.1); Has 30 Blast hits to 30
proteins in 10 species: Archae - 0; Bacteria - 0; Metazoa -
0; Fungi - 0; Plants - 30; Viruses - 0; Other Eukaryotes -
0 (source: NCBI BLink).		 -0.5 0.33 -0.33
30 AT2G17170 Protein kinase superfamily protein -0.5 0.34 -0.34
31 AT5G10740 Protein phosphatase 2C family protein -0.49 0.31 -0.32
32 AT3G04690 Malectin/receptor-like protein kinase family protein ANXUR1 0.49 0.32 -0.31
33 AT5G09850 Transcription elongation factor (TFIIS) family protein -0.49 0.32 -0.33
34 AT4G10460 transposable element gene -0.48 0.31 -0.31
35 AT2G37070 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT3G53320.1); Has 1323 Blast hits
to 775 proteins in 176 species: Archae - 0; Bacteria - 113;
Metazoa - 351; Fungi - 175; Plants - 115; Viruses - 13;
Other Eukaryotes - 556 (source: NCBI BLink).		 0.48 0.33 -0.27
36 AT2G17620 Cyclin B2;1 Cyclin B2;1 0.48 0.32 -0.31
37 AT2G35540 DNAJ heat shock N-terminal domain-containing protein -0.48 0.31 -0.32
38 AT1G54840 HSP20-like chaperones superfamily protein 0.47 0.34 -0.31
39 AT2G41451 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT3G57200.1); Has 30201
Blast hits to 17322 proteins in 780 species: Archae - 12;
Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants -
5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI
BLink).		 -0.47 0.33 -0.31
40 AT5G57650 eukaryotic translation initiation factor-related -0.47 0.32 -0.31
41 AT5G35750 histidine kinase 2 histidine kinase 2, histidine
kinase 2		 0.46 0.29 -0.34
42 AT2G16870 Disease resistance protein (TIR-NBS-LRR class) family 0.45 0.29 -0.32
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
43 C0219 Pyroglutamic acid (2R,2S)-Pyroglutamic acid 5-Oxoproline gamma-glutamyl cycle (plant pathway),
gamma-glutamyl cycle 		1 0.31 -0.31 C0219
44 C0252 Threonic acid D,L-Threonic acid L-Threonate ascorbic acid degradation 0.79 0.45 -0.46 C0252
45 C0166 MST_1705.1 - - - 0.72 0.43 -0.43
46 C0165 MST_1688.6 - - - -0.65 0.46 -0.45
47 C0164 MST_1596.8 - - - -0.64 0.48 -0.44
48 C0194 Phenylalanine D,L-Phenylalanine L-Phenylalanine suberin biosynthesis,
benzoate biosynthesis II (CoA-independent, non-beta-oxidative),
indole-3-acetyl-amino acid biosynthesis,
phenylalanine degradation III,
jasmonoyl-amino acid conjugates biosynthesis I,
trans-cinnamoyl-CoA biosynthesis,
phenylethanol biosynthesis,
phenylalanine biosynthesis II,
tRNA charging,
IAA degradation V,
glucosinolate biosynthesis from phenylalanine,
phenylpropanoid biosynthesis, initial reactions 		-0.56 0.33 -0.33 C0194
49 C0004 β-Alanine - β-Alanine uracil degradation II (reductive),
pantothenate biosynthesis,
beta-alanine biosynthesis II,
beta-alanine biosynthesis I 		0.52 0.3 -0.31 C0004
50 C0102 Glutamine D,L-Glutamine L-Glutamine ammonia assimilation cycle II,
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
purine nucleotides de novo biosynthesis II,
tetrahydrofolate biosynthesis II,
NAD biosynthesis I (from aspartate),
nitrate reduction II (assimilatory),
5-aminoimidazole ribonucleotide biosynthesis I,
citrulline biosynthesis,
pyrimidine ribonucleotides interconversion,
histidine biosynthesis,
indole-3-acetyl-amino acid biosynthesis,
pyridoxal 5'-phosphate biosynthesis II,
arginine biosynthesis I,
UDP-N-acetyl-D-glucosamine biosynthesis II,
pyridine nucleotide cycling (plants),
glutamate biosynthesis IV,
glutamine biosynthesis III,
glutamate biosynthesis V,
asparagine biosynthesis III (tRNA-dependent),
tryptophan biosynthesis,
L-glutamine biosynthesis II (tRNA-dependent),
uridine-5'-phosphate biosynthesis,
tRNA charging,
glutamine biosynthesis I,
arginine biosynthesis II (acetyl cycle),
asparagine biosynthesis I 		-0.5 0.32 -0.31 C0102
51 C0060 Asparagine D,L-Asparagine L-Asparagine asparagine degradation I,
asparagine biosynthesis III (tRNA-dependent),
asparagine biosynthesis I,
tRNA charging,
cyanide detoxification II 		-0.5 0.3 -0.3 C0060
52 C0209 Phosphoric acid - - ascorbate biosynthesis,
GDP biosynthesis,
polysaccharide biosynthesis 		0.5 0.31 -0.33