4.0:Information of module
shoot control pRBCS
In comparison with Col BTH help
Scatter plot of seleted modules.
Trend of Up regulated genes including module
GOID Term Ontology p-value
GO:0009853 photorespiration BP 1.388e-05
GO:0006457 protein folding BP 1.516e-05
GO:0009657 plastid organization BP 2.472e-05
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View Hierarchical networks of GOs (      )
Trend of Down regulated genes including module
GOID Term Ontology p-value
GO:0006354 DNA-templated transcription, elongation BP 8.194e-40
GO:0015979 photosynthesis BP 5.139e-28
GO:0006091 generation of precursor metabolites and ... BP 2.637e-18
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View Hierarchical networks of GOs (      )
List of genes in module
･･･up requlated genes  ･･･down regulated genes
probeID AGICode Annotation Log2 signal ratio
shoot control pRBCS		 Log2 signal ratio
Col BTH
1 245385_at AT4G14020 [Rapid alkalinization factor (RALF) family protein] 0.838 0.097
2 260672_at AT1G19480 [DNA glycosylase superfamily protein] 0.557 -0.072
3 258315_at AT3G16175 [Thioesterase superfamily protein] 0.436 -0.072
4 247024_at AT5G66985 unknown 0.435 -0.068
5 262902_x_at AT1G59930 [MADS-box family protein] 0.429 0.104
6 245505_at AT4G15690 [Thioredoxin superfamily protein] 0.426 -0.038
7 247291_at AT5G64480 unknown 0.421 -0.036
8 265837_at AT2G14560 LURP1, LATE UPREGULATED IN RESPONSE TO HYALOPERONOSPORA PARASITICA 0.412 0.234
9 259879_at AT1G76650 CML38, calmodulin-like 38 0.387 -0.067
10 255941_at AT1G20350 ATTIM17-1, translocase inner membrane subunit 17-1, TIM17-1, translocase inner membrane subunit 17-1 0.379 0.355
11 246518_at AT5G15770 AtGNA1, glucose-6-phosphate acetyltransferase 1, GNA1, glucose-6-phosphate acetyltransferase 1 0.377 0.019
12 259423_at AT1G13880 [ELM2 domain-containing protein] 0.358 0.023
13 260076_at AT1G73630 [EF hand calcium-binding protein family] 0.351 -0.106
14 266800_at AT2G22880 [VQ motif-containing protein] 0.347 -0.134
15 252661_at AT3G44450 unknown 0.339 -0.107
16 250650_at AT5G06850 FTIP1, FT-interacting protein 1 0.335 -0.076
17 264974_at AT1G27050 [homeobox protein 54 (HB54)] 0.324 -0.033
18 246653_at AT5G35200 [ENTH/ANTH/VHS superfamily protein] 0.316 0.082
19 251985_at AT3G53220 [Thioredoxin superfamily protein] 0.316 -0.055
20 261938_at AT1G22510 [FUNCTIONS IN: zinc ion binding] 0.312 0.075
21 247656_at AT5G59890 ADF4, actin depolymerizing factor 4, ATADF4 0.306 -0.007
22 245747_at AT1G51100 CRR41, CHLORORESPIRATORY REDUCTION 41 0.302 -0.218
23 253940_at AT4G26950 unknown 0.301 -0.089
24 253207_at AT4G34770 SAUR1, SMALL AUXIN UPREGULATED RNA 1 0.291 0.025
25 258928_at AT3G10070 TAF12, TBP-associated factor 12, TAFII58, TATA-ASSOCIATED FACTOR II 58 0.283 -0.035
26 261286_at AT1G35780 unknown 0.282 -0.053
27 247255_at AT5G64780 [Uncharacterised conserved protein UCP009193] 0.280 0.046
28 247836_at AT5G57860 [Ubiquitin-like superfamily protein] 0.280 0.033
29 263593_at AT2G01860 EMB975, EMBRYO DEFECTIVE 975 0.280 0.038
30 263584_at AT2G17040 anac036, NAC domain containing protein 36, NAC036, NAC domain containing protein 36 0.274 0.146
31 246007_at AT5G08410 FTRA2, ferredoxin/thioredoxin reductase subunit A (variable subunit) 2 0.272 -0.087
32 247632_at AT5G60460 [Preprotein translocase Sec, Sec61-beta subunit protein] 0.271 0.027
33 251454_at AT3G60080 [RING/U-box superfamily protein] 0.270 -0.037
34 254661_at AT4G18260 [Cytochrome b561/ferric reductase transmembrane protein family] 0.269 0.022
35 250603_at AT5G07820 [Plant calmodulin-binding protein-related] 0.267 0.243
36 265044_at AT1G03950 VPS2.3, vacuolar protein sorting-associated protein 2.3 0.266 0.015
37 245337_at AT4G16566 HINT4, histidine triad nucleotide-binding 4 0.265 -0.000
38 246522_at AT5G15830 AtbZIP3, basic leucine-zipper 3, bZIP3, basic leucine-zipper 3 0.258 -0.053
39 249404_at AT5G40160 EMB139, EMBRYO DEFECTIVE 139, EMB506, embryo defective 506 0.256 -0.071
40 256503_at AT1G75250 ATRL6, RAD-like 6, RL6, RAD-like 6, RSM3, RADIALIS-LIKE SANT/MYB 3 0.256 -0.117
41 259497_at AT1G15860 unknown 0.254 0.023
42 265226_at AT2G28430 unknown 0.254 -0.022
43 254276_at AT4G22820 [A20/AN1-like zinc finger family protein] 0.250 -0.024
44 267070_at AT2G41000 [Chaperone DnaJ-domain superfamily protein] 0.248 -0.018
45 245545_at AT4G15280 UGT71B5, UDP-glucosyl transferase 71B5 0.247 0.014
46 251727_at AT3G56290 unknown 0.244 0.022
47 250515_at AT5G09570 [Cox19-like CHCH family protein] 0.244 -0.025
48 260367_at AT1G69760 unknown 0.242 0.237
49 261733_at AT1G47830 [SNARE-like superfamily protein] 0.240 0.005
50 256767_at AT3G13680 [F-box and associated interaction domains-containing protein] 0.239 -0.075
51 263497_at AT2G42540 COR15, COR15A, cold-regulated 15a 0.239 -0.376
52 248282_at AT5G52900 MAKR6, MEMBRANE-ASSOCIATED KINASE REGULATOR 6 0.239 0.249
53 261516_at AT1G71750 HGPT, Hypoxanthine-guanine phosphoribosyltransferase 0.239 -0.002
54 246159_at AT5G20935 CRR42, CHLORORESPIRATORY REDUCTION 42 0.238 -0.110
55 260427_at AT1G72430 SAUR78, SMALL AUXIN UPREGULATED RNA 78 0.234 0.113
56 262196_at AT1G77870 MUB5, membrane-anchored ubiquitin-fold protein 5 precursor 0.233 -0.121
57 257698_at AT3G12730 [Homeodomain-like superfamily protein] 0.231 -0.053
58 259659_at AT1G55170 unknown 0.230 -0.022
59 247754_at AT5G59080 unknown 0.228 0.014
60 258920_at AT3G10520 AHB2, haemoglobin 2, ARATH GLB2, ATGLB2, ARABIDOPSIS HEMOGLOBIN 2, GLB2, HEMOGLOBIN 2, HB2, haemoglobin 2, NSHB2, NON-SYMBIOTIC HAEMOGLOBIN 2 0.227 -0.059
61 260622_at AT1G07980 NF-YC10, nuclear factor Y, subunit C10 0.227 -0.014
62 262160_at AT1G52590 [Putative thiol-disulphide oxidoreductase DCC] 0.227 -0.017
63 250353_at AT5G11630 NOXY2, nonresponding to oxylipins 2 0.226 0.022
64 262050_at AT1G80130 [Tetratricopeptide repeat (TPR)-like superfamily protein] 0.225 0.062
65 247420_at AT5G63100 [S-adenosyl-L-methionine-dependent methyltransferases superfamily protein] 0.223 -0.176
66 257624_at AT3G26220 CYP71B3, cytochrome P450, family 71, subfamily B, polypeptide 3 0.222 0.446
67 252063_at AT3G51590 LTP12, lipid transfer protein 12 0.221 -0.004
68 265214_at AT1G05000 AtPFA-DSP1, PFA-DSP1, plant and fungi atypical dual-specificity phosphatase 1 0.220 0.169
69 263331_at AT2G15270 unknown 0.220 0.052
70 267467_at AT2G30580 BMI1A, DRIP2, DREB2A-interacting protein 2 0.218 0.070
71 265183_at AT1G23750 [Nucleic acid-binding, OB-fold-like protein] 0.218 -0.076
72 252565_at AT3G46000 ADF2, actin depolymerizing factor 2 0.217 -0.005
73 249087_at AT5G44210 ATERF-9, ERF DOMAIN PROTEIN- 9, ATERF9, ERF DOMAIN PROTEIN 9, ERF9, erf domain protein 9 0.217 -0.004
74 249878_at AT5G23090 NF-YB13, nuclear factor Y, subunit B13 0.216 0.054
75 251008_at AT5G02710 unknown 0.216 -0.016
76 258956_at AT3G01440 PnsL3, Photosynthetic NDH subcomplex L 3, PQL1, PsbQ-like 1, PQL2, PsbQ-like 2 0.216 -0.120
77 246218_at AT4G36800 RCE1, RUB1 conjugating enzyme 1 0.215 -0.014
78 258640_at AT3G07930 [DNA glycosylase superfamily protein] 0.214 -0.000
79 246140_at AT5G19910 MED31 0.214 -0.025
80 262974_at AT1G75550 [glycine-rich protein] 0.213 -0.083
81 253302_at AT4G33660 unknown 0.212 -0.067
82 247753_at AT5G59070 [UDP-Glycosyltransferase superfamily protein] 0.211 0.062
83 258915_at AT3G10640 VPS60.1 0.211 0.073
84 255088_at AT4G09350 CRRJ, CHLORORESPIRATORY REDUCTION J, DJC75, DNA J protein C75, NdhT, NADH dehydrogenase-like complex T 0.210 -0.232
85 252373_at AT3G48090 ATEDS1, EDS1, enhanced disease susceptibility 1 0.210 0.230
86 254611_at AT4G19095 unknown 0.210 -0.025
87 248379_at AT5G51700 ATRAR1, PBS2, PPHB SUSCEPTIBLE 2, RAR1, Required for Mla12 resistance 1, RPR2 0.210 0.020
88 248632_at AT5G49010 EMB2812, EMBRYO DEFECTIVE 2812, SLD5, SYNTHETIC LETHALITY WITH DPB11-1 5 0.209 -0.072
89 252223_at AT3G49850 ATTRB3, TBP2, TELOMERE-BINDING PROTEIN 2, TRB3, telomere repeat binding factor 3 0.209 -0.003
90 265510_at AT2G05630 ATG8D 0.208 0.109
91 257373_at AT2G43140 [basic helix-loop-helix (bHLH) DNA-binding superfamily protein] 0.208 0.132
92 251986_at AT3G53310 [AP2/B3-like transcriptional factor family protein] 0.207 0.151
93 265093_at AT1G03905 ABCI19, ATP-binding cassette I19 0.207 0.037
94 254891_at AT4G11740 SAY1 0.207 0.046
95 262107_at AT1G02750 [Drought-responsive family protein] 0.207 0.043
96 252650_at AT3G44690 unknown 0.206 -0.011
97 256384_at AT1G66660 [Protein with RING/U-box and TRAF-like domains] 0.205 0.048
98 258972_at AT3G01920 [DHBP synthase RibB-like alpha/beta domain] 0.205 -0.101
99 261487_at AT1G14340 [RNA-binding (RRM/RBD/RNP motifs) family protein] 0.204 0.021
100 265913_at AT2G25625 unknown 0.204 -0.037
101 262622_at AT1G06510 unknown 0.204 -0.059
102 248910_at AT5G45820 CIPK20, CBL-interacting protein kinase 20, PKS18, PROTEIN KINASE 18, SnRK3.6, SNF1-RELATED PROTEIN KINASE 3.6 0.204 -0.167
103 251197_at AT3G62960 [Thioredoxin superfamily protein] 0.203 0.083
104 260741_at AT1G15040 GAT, glutamine amidotransferase, GAT1_2.1, glutamine amidotransferase 1_2.1 0.202 0.047
105 267123_at AT2G23560 ATMES7, ARABIDOPSIS THALIANA METHYL ESTERASE 7, MES7, methyl esterase 7 0.200 -0.298
106 266570_at AT2G24090 PRPL35, plastid ribosomal protein L35 0.198 -0.049
107 266393_at AT2G41260 ATM17, M17 -1.264 -0.071
108 266353_at AT2G01520 MLP328, MLP-like protein 328, ZCE1, (Zusammen-CA)-enhanced 1 -1.038 0.023
109 265211_at AT2G36640 ATECP63, embryonic cell protein 63, ECP63, embryonic cell protein 63 -1.003 0.008
110 244981_at ATCG00770 RPS8, ribosomal protein S8 -0.999 -0.001
111 266544_at AT2G35300 AtLEA4-2, late embryogenesis abundant 4-2, LEA18, late embryogenesis abundant 18, LEA4-2, late embryogenesis abundant 4-2 -0.946 0.018
112 256814_at AT3G21370 BGLU19, beta glucosidase 19 -0.886 0.012
113 244985_at ATCG00810 RPL22, ribosomal protein L22 -0.848 0.013
114 258347_at AT3G17520 [Late embryogenesis abundant protein (LEA) family protein] -0.841 0.051
115 252019_at AT3G53040 [late embryogenesis abundant protein, putative / LEA protein, putative] -0.832 0.026
116 245049_at ATCG00050 RPS16, ribosomal protein S16 -0.794 -0.061
117 251838_at AT3G54940 [Papain family cysteine protease] -0.788 -0.007
118 250624_at AT5G07330 unknown -0.784 -0.038
119 244939_at ATCG00065 RPS12, RIBOSOMAL PROTEIN S12, RPS12A, ribosomal protein S12A -0.783 -0.078
120 256464_at AT1G32560 AtLEA4-1, Late Embryogenesis Abundant 4-1, LEA4-1, Late Embryogenesis Abundant 4-1 -0.779 -0.047
121 262482_at AT1G17020 ATSRG1, SENESCENCE-RELATED GENE 1, SRG1, senescence-related gene 1 -0.778 0.241
122 244980_at ATCG00760 RPL36, ribosomal protein L36 -0.767 -0.027
123 244966_at ATCG00600 PETG -0.751 -0.085
124 262128_at AT1G52690 LEA7, LATE EMBRYOGENESIS ABUNDANT 7 -0.750 0.115
125 245016_at ATCG00500 ACCD, acetyl-CoA carboxylase carboxyl transferase subunit beta -0.717 -0.079
126 245008_at ATCG00360 YCF3 -0.709 -0.162
127 244932_at ATCG01060 PSAC -0.692 -0.045
128 260097_at AT1G73220 AtOCT1, organic cation/carnitine transporter1, OCT1, organic cation/carnitine transporter1 -0.688 -0.009
129 256354_at AT1G54870 [NAD(P)-binding Rossmann-fold superfamily protein] -0.663 -0.022
130 244970_at ATCG00660 RPL20, ribosomal protein L20 -0.661 -0.072
131 245555_at AT4G15390 [HXXXD-type acyl-transferase family protein] -0.646 -0.042
132 247437_at AT5G62490 ATHVA22B, ARABIDOPSIS THALIANA HVA22 HOMOLOGUE B, HVA22B, HVA22 homologue B -0.636 -0.069
133 247095_at AT5G66400 ATDI8, ARABIDOPSIS THALIANA DROUGHT-INDUCED 8, RAB18, RESPONSIVE TO ABA 18 -0.633 -0.107
134 266462_at AT2G47770 ATTSPO, TSPO(outer membrane tryptophan-rich sensory protein)-related, TSPO, TSPO(outer membrane tryptophan-rich sensory protein)-related -0.630 0.051
135 252102_at AT3G50970 LTI30, LOW TEMPERATURE-INDUCED 30, XERO2 -0.628 0.088
136 245011_at ATCG00430 PSBG, photosystem II reaction center protein G -0.623 -0.153
137 250868_at AT5G03860 MLS, malate synthase -0.619 -0.001
138 244933_at ATCG01070 NDHE -0.619 -0.121
139 253392_at AT4G32650 ATKC1, ARABIDOPSIS THALIANA K+ RECTIFYING CHANNEL 1, AtLKT1, A. thaliana low-K+-tolerant 1, KAT3, potassium channel in Arabidopsis thaliana 3, KC1 -0.616 0.052
140 250500_at AT5G09530 PELPK1, Pro-Glu-Leu|Ile|Val-Pro-Lys 1, PRP10, proline-rich protein 10 -0.608 0.036
141 256338_at AT1G72100 [late embryogenesis abundant domain-containing protein / LEA domain-containing protein] -0.597 0.047
142 251942_at AT3G53480 ABCG37, ATP-binding cassette G37, ATPDR9, PLEIOTROPIC DRUG RESISTANCE 9, PDR9, pleiotropic drug resistance 9, PIS1, polar auxin transport inhibitor sensitive 1 -0.594 -0.092
143 245017_at ATCG00510 PSAI, photsystem I subunit I -0.587 -0.083
144 247297_at AT5G64100 [Peroxidase superfamily protein] -0.586 -0.052
145 244982_at ATCG00780 RPL14, ribosomal protein L14 -0.580 -0.005
146 257334_at ATMG01370 ORF111D -0.576 0.008
147 253660_at AT4G30140 CDEF1, CUTICLE DESTRUCTING FACTOR 1 -0.573 -0.130
148 245021_at ATCG00550 PSBJ, photosystem II reaction center protein J -0.561 0.019
149 244963_at ATCG00570 PSBF, photosystem II reaction center protein F -0.558 -0.002
150 258895_at AT3G05600 [alpha/beta-Hydrolases superfamily protein] -0.556 -0.131
151 262644_at AT1G62710 BETA-VPE, beta vacuolar processing enzyme, BETAVPE -0.553 -0.004
152 244984_at ATCG00800 [RESISTANCE TO PSEUDOMONAS SYRINGAE 3 (RPS3)] -0.549 0.031
153 260088_at AT1G73190 ALPHA-TIP, ALPHA-TONOPLAST INTRINSIC PROTEIN, TIP3;1 -0.543 -0.024
154 253191_at AT4G35350 XCP1, xylem cysteine peptidase 1 -0.542 -0.127
155 248728_at AT5G48000 CYP708 A2, CYTOCHROME P450, FAMILY 708, SUBFAMILY A, POLYPEPTIDE 2, CYP708A2, cytochrome P450, family 708, subfamily A, polypeptide 2, THAH, THALIANOL HYDROXYLASE, THAH1, THALIANOL HYDROXYLASE 1 -0.541 -0.014
156 266143_at AT2G38905 [Low temperature and salt responsive protein family] -0.540 -0.017
157 244996_at ATCG00160 RPS2, ribosomal protein S2 -0.530 -0.061
158 244934_at ATCG01080 NDHG -0.526 -0.127
159 244964_at ATCG00580 PSBE, photosystem II reaction center protein E -0.516 -0.003
160 248727_at AT5G47990 CYP705A5, cytochrome P450, family 705, subfamily A, polypeptide 5, THAD, THALIAN-DIOL DESATURASE, THAD1, THALIAN-DIOL DESATURASE -0.503 -0.017
161 248912_at AT5G45670 [GDSL-like Lipase/Acylhydrolase superfamily protein] -0.501 -0.130
162 244979_at ATCG00750 RPS11, ribosomal protein S11 -0.500 -0.021
163 245010_at ATCG00420 NDHJ, NADH dehydrogenase subunit J -0.500 -0.155
164 249045_at AT5G44380 [FAD-binding Berberine family protein] -0.499 -0.048
165 263098_at AT2G16005 [MD-2-related lipid recognition domain-containing protein] -0.496 -0.003
166 266941_at AT2G18980 [Peroxidase superfamily protein] -0.495 -0.020
167 264166_at AT1G65370 [TRAF-like family protein] -0.490 0.100
168 260166_at AT1G79840 GL2, GLABRA 2 -0.486 -0.078
169 244936_at ATCG01100 NDHA -0.485 0.001
170 253073_at AT4G37410 CYP81F4, cytochrome P450, family 81, subfamily F, polypeptide 4 -0.482 -0.157
171 244998_at ATCG00180 RPOC1 -0.480 -0.064
172 245018_at ATCG00520 YCF4 -0.476 -0.083
173 245019_at ATCG00530 YCF10 -0.462 -0.054
174 245015_at ATCG00490 RBCL -0.460 -0.045
175 244997_at ATCG00170 RPOC2 -0.458 -0.132
176 247061_at AT5G66780 unknown -0.457 0.034
177 252989_at AT4G38420 sks9, SKU5 similar 9 -0.455 -0.096
178 258863_at AT3G03300 ATDCL2, DICER-LIKE 2, DCL2, dicer-like 2 -0.455 0.035
179 254633_at AT4G18640 MRH1, morphogenesis of root hair 1 -0.454 -0.178
180 263485_at AT2G29890 ATVLN1, VLN1, villin 1 -0.449 -0.046
181 261845_at AT1G15960 ATNRAMP6, NRAMP6, NRAMP metal ion transporter 6 -0.447 0.134
182 267645_at AT2G32860 BGLU33, beta glucosidase 33 -0.444 -0.122
183 245022_at ATCG00560 PSBL, photosystem II reaction center protein L -0.441 0.025
184 245009_at ATCG00380 RPS4, chloroplast ribosomal protein S4 -0.441 -0.093
185 260890_at AT1G29090 [Cysteine proteinases superfamily protein] -0.438 0.057
186 265672_at AT2G31980 AtCYS2, PHYTOCYSTATIN 2, CYS2, PHYTOCYSTATIN 2 -0.436 -0.068
187 250648_at AT5G06760 AtLEA4-5, Late Embryogenesis Abundant 4-5, LEA4-5, Late Embryogenesis Abundant 4-5 -0.435 -0.040
188 254543_at AT4G19810 ChiC, class V chitinase -0.433 0.077
189 244986_at ATCG00820 RPS19, ribosomal protein S19 -0.433 -0.012
190 261653_at AT1G01900 ATSBT1.1, SBTI1.1 -0.431 -0.141
191 261930_at AT1G22440 [Zinc-binding alcohol dehydrogenase family protein] -0.427 0.035
192 252537_at AT3G45710 [Major facilitator superfamily protein] -0.427 0.007
193 249542_at AT5G38140 NF-YC12, nuclear factor Y, subunit C12 -0.422 0.111
194 259615_at AT1G47980 unknown -0.420 0.235
195 257217_at AT3G14940 ATPPC3, phosphoenolpyruvate carboxylase 3, PPC3, phosphoenolpyruvate carboxylase 3 -0.420 -0.125
196 254327_at AT4G22490 [Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein] -0.415 -0.022
197 244937_at ATCG01110 NDHH, NAD(P)H dehydrogenase subunit H -0.411 -0.078
198 249567_at AT5G38020 [S-adenosyl-L-methionine-dependent methyltransferases superfamily protein] -0.402 0.016
199 244943_at ATMG00070 NAD9, NADH dehydrogenase subunit 9 -0.402 0.007
200 262796_at AT1G20850 XCP2, xylem cysteine peptidase 2 -0.401 -0.074
201 264469_at AT1G67100 LBD40, LOB domain-containing protein 40 -0.401 0.014
202 265250_at AT2G01950 BRL2, BRI1-like 2, VH1, VASCULAR HIGHWAY 1 -0.400 -0.112
203 256321_at AT1G55020 ATLOX1, ARABIDOPSIS LIPOXYGENASE 1, LOX1, lipoxygenase 1 -0.395 -0.150
204 245014_at ATCG00480 ATPB, ATP synthase subunit beta, PB, ATP synthase subunit beta -0.394 -0.008
205 250228_at AT5G13840 CCS52B, cell cycle switch protein 52 B, FZR3, FIZZY-related 3 -0.392 0.055
206 261991_at AT1G33700 [Beta-glucosidase, GBA2 type family protein] -0.388 0.014
207 253753_at AT4G29030 [Putative membrane lipoprotein] -0.387 -0.019
208 248729_at AT5G48010 AtTHAS1, Arabidopsis thaliana thalianol synthase 1, THAS, THALIANOL SYNTHASE, THAS1, thalianol synthase 1 -0.385 -0.044
209 267595_at AT2G32990 AtGH9B8, glycosyl hydrolase 9B8, GH9B8, glycosyl hydrolase 9B8 -0.383 -0.261
210 251668_at AT3G57010 [Calcium-dependent phosphotriesterase superfamily protein] -0.382 -0.165
211 244962_at ATCG01050 NDHD -0.381 -0.037
212 265902_at AT2G25590 [Plant Tudor-like protein] -0.376 0.220