C0092 : Fumaric acid
Query Information
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ID C0092
Compound name Fumaric acid
External link   http://pmn.plantcyc.org/ARA/NEW-IMAGE?type=COMPOUND&object=FUM
Pathway Information citrulline-nitric oxide cycle,
succinate + a ubiquinone -> a ubiquinol + fumarate,
superpathway of glyoxylate cycle and fatty acid degradation,
tyrosine degradation I,
aerobic respiration (alternative oxidase pathway),
inosine-5'-phosphate biosynthesis II,
arginine biosynthesis I,
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
purine nucleotides de novo biosynthesis II,
arginine biosynthesis II (acetyl cycle),
urea cycle,
aerobic respiration (cytochrome c)
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT4G34750 SAUR-like auxin-responsive protein family -0.78 0.32 -0.31
2 AT3G22750 Protein kinase superfamily protein -0.77 0.31 -0.33
3 AT4G33040 Thioredoxin superfamily protein 0.76 0.33 -0.31
4 AT2G24420 DNA repair ATPase-related 0.76 0.32 -0.32
5 AT2G22240 myo-inositol-1-phosphate synthase 2 INOSITOL 3-PHOSPHATE SYNTHASE 2,
MYO-INOSITOL-1-PHOSTPATE SYNTHASE
2, myo-inositol-1-phosphate
synthase 2		 0.76 0.32 -0.32
6 AT1G31750 proline-rich family protein 0.75 0.33 -0.32
7 AT3G49940 LOB domain-containing protein 38 LOB domain-containing protein 38 -0.75 0.32 -0.31
8 AT3G61970 AP2/B3-like transcriptional factor family protein NGATHA2 0.74 0.33 -0.32
9 AT5G64100 Peroxidase superfamily protein -0.74 0.32 -0.32
10 AT5G01820 serine/threonine protein kinase 1 ATCIPK14, serine/threonine protein
kinase 1, CBL-INTERACTING PROTEIN
KINASE 14, SOS2-like protein
kinase 24, SNF1-RELATED PROTEIN
KINASE 3.15, serine/threonine
protein kinase 1		 0.73 0.31 -0.33
11 AT1G29395 COLD REGULATED 314 INNER MEMBRANE 1 COLD REGULATED 314 THYLAKOID
MEMBRANE 1, COLD REGULATED 314
INNER MEMBRANE 1, cold regulated
414 thylakoid membrane 1		 0.73 0.32 -0.33
12 AT4G36670 Major facilitator superfamily protein AtPLT6, AtPMT6, polyol transporter
6, polyol/monosaccharide
transporter 6		 -0.73 0.32 -0.3
13 AT4G37540 LOB domain-containing protein 39 LOB domain-containing protein 39 -0.73 0.3 -0.32
14 AT4G31460 Ribosomal L28 family -0.73 0.32 -0.33
15 AT1G62310 transcription factor jumonji (jmjC) domain-containing
protein		 0.72 0.31 -0.32
16 AT2G01900 DNAse I-like superfamily protein -0.72 0.33 -0.32
17 AT5G65890 ACT domain repeat 1 ACT domain repeat 1 0.72 0.33 -0.32
18 AT1G29390 cold regulated 314 thylakoid membrane 2 cold regulated 314 thylakoid
membrane 2, COLD REGULATED 314
INNER MEMBRANE 2		 0.72 0.3 -0.32
19 AT2G14460 unknown protein; Has 3 Blast hits to 3 proteins in 1
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 3; Viruses - 0; Other Eukaryotes - 0 (source: NCBI
BLink).		 -0.72 0.31 -0.31
20 AT2G39450 Cation efflux family protein ATMTP11, MTP11 0.72 0.32 -0.29
21 AT4G34100 RING/U-box superfamily protein 0.71 0.32 -0.31
22 AT3G19620 Glycosyl hydrolase family protein 0.71 0.33 -0.31
23 AT2G31810 ACT domain-containing small subunit of acetolactate
synthase protein		 -0.71 0.34 -0.29
24 AT5G56870 beta-galactosidase 4 beta-galactosidase 4 -0.7 0.32 -0.31
25 AT3G16770 ethylene-responsive element binding protein ethylene-responsive element
binding protein,
ethylene-responsive element
binding protein, ETHYLENE RESPONSE
FACTOR 72, RELATED TO AP2 3		 -0.7 0.3 -0.33
26 AT2G47790 Transducin/WD40 repeat-like superfamily protein -0.7 0.3 -0.31
27 AT1G71480 Nuclear transport factor 2 (NTF2) family protein 0.7 0.33 -0.31
28 AT5G62130 Per1-like family protein 0.7 0.31 -0.33
29 AT1G13300 myb-like transcription factor family protein HYPERSENSITIVITY TO LOW
PI-ELICITED PRIMARY ROOT
SHORTENING 1		 -0.7 0.29 -0.3
30 AT5G51890 Peroxidase superfamily protein 0.69 0.31 -0.31
31 AT5G20640 Protein of unknown function (DUF567) -0.69 0.31 -0.34
32 AT5G48370 Thioesterase/thiol ester dehydrase-isomerase superfamily
protein		 0.69 0.32 -0.3
33 AT5G43600 ureidoglycolate amidohydrolase ARABIDOPSIS THALIANA ALLANTOATE
AMIDOHYDROLASE 2, ureidoglycolate
amidohydrolase		 0.69 0.33 -0.33
34 AT4G02420 Concanavalin A-like lectin protein kinase family protein 0.68 0.34 -0.3
35 AT4G18800 RAB GTPase homolog A1D ATHSGBP, ATRAB11B, RAB GTPase
homolog A1D, RAB GTPase homolog
A1D		 -0.68 0.32 -0.33
36 AT1G80460 Actin-like ATPase superfamily protein GLI1, nonhost resistance to P. s.
phaseolicola 1		 -0.68 0.31 -0.3
37 AT5G16070 TCP-1/cpn60 chaperonin family protein -0.68 0.34 -0.31
38 AT2G36690 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase
superfamily protein		 -0.68 0.3 -0.32
39 AT1G44830 Integrase-type DNA-binding superfamily protein -0.68 0.3 -0.29
40 AT5G23405 HMG-box (high mobility group) DNA-binding family protein -0.68 0.32 -0.33
41 AT2G44790 uclacyanin 2 uclacyanin 2 -0.68 0.31 -0.31
42 AT2G20770 GCR2-like 2 GCR2-like 2 0.68 0.33 -0.31
43 AT2G21340 MATE efflux family protein 0.67 0.3 -0.3
44 AT3G14840 Leucine-rich repeat transmembrane protein kinase -0.67 0.32 -0.31
45 AT5G03650 starch branching enzyme 2.2 starch branching enzyme 2.2 0.67 0.29 -0.31
46 AT1G17440 Transcription initiation factor TFIID subunit A CYTOKININ-HYPERSENSITIVE 1,
ENHANCED ETHYLENE RESPONSE 4,
TBP-ASSOCIATED FACTOR 12B		 0.67 0.31 -0.32
47 AT4G15700 Thioredoxin superfamily protein -0.67 0.31 -0.31
48 AT2G44380 Cysteine/Histidine-rich C1 domain family protein -0.67 0.34 -0.29
49 AT5G57160 DNA ligase IV ATLIG4, DNA LIGASE IV -0.67 0.33 -0.31
50 AT5G53130 cyclic nucleotide gated channel 1 CYCLIC NUCLEOTIDE-GATED CHANNEL 1,
cyclic nucleotide gated channel 1		 0.66 0.3 -0.31
51 AT3G02885 GAST1 protein homolog 5 GAST1 protein homolog 5 -0.66 0.31 -0.33
52 AT4G23990 cellulose synthase like G3 ARABIDOPSIS THALIANA CELLULOSE
SYNTHASE-LIKE G3, cellulose
synthase like G3		 0.66 0.3 -0.3
53 AT5G51770 Protein kinase superfamily protein 0.65 0.33 -0.32
54 AT5G15610 Proteasome component (PCI) domain protein -0.65 0.31 -0.28
55 AT4G18430 RAB GTPase homolog A1E RAB GTPase homolog A1E, RAB GTPase
homolog A1E		 -0.65 0.31 -0.32
56 AT2G19780 Leucine-rich repeat (LRR) family protein 0.65 0.31 -0.33
57 AT2G19385 zinc ion binding -0.65 0.3 -0.31
58 AT1G76350 Plant regulator RWP-RK family protein 0.65 0.31 -0.31
59 ATMG01290 hypothetical protein ORF111C -0.65 0.32 -0.31
60 AT2G40840 disproportionating enzyme 2 disproportionating enzyme 2 0.65 0.32 -0.3
61 AT3G11220 Paxneb protein-related ELONGATA 1 -0.64 0.31 -0.32
62 AT2G33290 SU(VAR)3-9 homolog 2 ATSUVH2, SET DOMAIN-CONTAINING
PROTEIN 3, SU(VAR)3-9 homolog 2		 -0.64 0.3 -0.32
63 AT5G43520 Cysteine/Histidine-rich C1 domain family protein -0.64 0.31 -0.33
64 AT4G15680 Thioredoxin superfamily protein -0.64 0.32 -0.3
65 AT5G19180 E1 C-terminal related 1 E1 C-terminal related 1 -0.64 0.3 -0.3
66 AT5G01770 HEAT repeat ;WD domain, G-beta repeat protein protein ATRAPTOR1A, RAPTOR1A, RAPTOR2 0.64 0.32 -0.3
67 AT1G24530 Transducin/WD40 repeat-like superfamily protein -0.64 0.33 -0.32
68 AT3G56050 Protein kinase family protein 0.63 0.32 -0.31
69 AT2G45860 unknown protein; Has 32 Blast hits to 32 proteins in 13
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 32; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 -0.63 0.3 -0.33
70 AT1G36060 Integrase-type DNA-binding superfamily protein -0.63 0.33 -0.31
71 AT1G31850 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 -0.63 0.33 -0.31
72 AT5G27920 F-box family protein -0.63 0.32 -0.34
73 AT5G66320 GATA transcription factor 5 GATA transcription factor 5 0.63 0.3 -0.31
74 AT4G02230 Ribosomal protein L19e family protein -0.63 0.31 -0.31
75 AT1G65930 cytosolic NADP+-dependent isocitrate dehydrogenase cytosolic NADP+-dependent
isocitrate dehydrogenase		 -0.63 0.35 -0.29
76 AT1G10590 Nucleic acid-binding, OB-fold-like protein -0.63 0.32 -0.31
77 AT3G47840 Tetratricopeptide repeat (TPR)-like superfamily protein -0.63 0.32 -0.28
78 AT3G22320 Eukaryotic rpb5 RNA polymerase subunit family protein ATRPABC24.3, NRPB5, NRPD5, RNA
POLYMERASE II FIFTH LARGEST
SUBUNIT, A		 -0.63 0.31 -0.31
79 AT3G45680 Major facilitator superfamily protein 0.63 0.32 -0.32
80 AT3G01670 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT3G01680.1); Has 121 Blast hits
to 111 proteins in 12 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 121; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 sieve element occlusion a 0.63 0.31 -0.3
81 AT5G05430 RNA-binding protein -0.63 0.28 -0.31
82 AT1G66380 myb domain protein 114 myb domain protein 114, myb domain
protein 114		 0.62 0.34 -0.32
83 AT4G03820 Protein of unknown function (DUF3537) 0.62 0.3 -0.32
84 AT3G14067 Subtilase family protein 0.62 0.31 -0.3
85 AT3G10680 HSP20-like chaperones superfamily protein 0.62 0.31 -0.31
86 AT1G51730 Ubiquitin-conjugating enzyme family protein -0.62 0.33 -0.31
87 AT3G15630 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED
DURING: 15 growth stages; BEST Arabidopsis thaliana protein
match is: unknown protein (TAIR:AT1G52720.1); Has 61 Blast
hits to 61 proteins in 13 species: Archae - 0; Bacteria -
0; Metazoa - 0; Fungi - 0; Plants - 61; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.62 0.31 -0.34
88 AT1G02390 glycerol-3-phosphate acyltransferase 2 ARABIDOPSIS THALIANA
GLYCEROL-3-PHOSPHATE
ACYLTRANSFERASE 2,
glycerol-3-phosphate
acyltransferase 2		 0.62 0.32 -0.32
89 AT1G02900 rapid alkalinization factor 1 RAPID ALKALINIZATION FACTOR 1,
rapid alkalinization factor 1,
RALF-LIKE 1		 -0.62 0.31 -0.31
90 AT5G40270 HD domain-containing metal-dependent phosphohydrolase
family protein		 0.62 0.31 -0.33
91 AT3G58560 DNAse I-like superfamily protein -0.61 0.31 -0.32
92 AT3G53740 Ribosomal protein L36e family protein -0.61 0.31 -0.31
93 AT5G23020 2-isopropylmalate synthase 2 2-isopropylmalate synthase 2,
METHYLTHIOALKYMALATE
SYNTHASE-LIKE, MAM3		 -0.61 0.3 -0.31
94 AT5G53160 regulatory components of ABA receptor 3 PYR1-like 8, regulatory components
of ABA receptor 3		 -0.61 0.33 -0.34
95 AT4G25110 metacaspase 2 metacaspase 2, metacaspase 1c,
metacaspase 2, metacaspase 1c		 -0.61 0.31 -0.32
96 AT3G60550 cyclin p3;2 cyclin p3;2 -0.61 0.32 -0.33
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
97 C0092 Fumaric acid - Fumarate citrulline-nitric oxide cycle,
succinate + a ubiquinone -> a ubiquinol + fumarate,
superpathway of glyoxylate cycle and fatty acid degradation,
tyrosine degradation I,
aerobic respiration (alternative oxidase pathway),
inosine-5'-phosphate biosynthesis II,
arginine biosynthesis I,
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
purine nucleotides de novo biosynthesis II,
arginine biosynthesis II (acetyl cycle),
urea cycle,
aerobic respiration (cytochrome c) 		1 0.29 -0.32 C0092
98 C0170 MST_2128.3 - - - 0.84 0.48 -0.43
99 C0111 Hexa-2-O-glycerol-β-galactopyranoside Hexa-2-O-gllycerol-β-D-galactopyranoside - - 0.83 0.42 -0.45
100 C0123 Isoleucine D,L-Isoleucine L-Isoleucine tRNA charging,
isoleucine biosynthesis I (from threonine),
jasmonoyl-amino acid conjugates biosynthesis I,
isoleucine degradation I 		0.83 0.44 -0.49 C0123
101 C0210 Phytol E-Phytol Phytol chlorophyll a degradation II,
chlorophyll a degradation,
phytol salvage pathway 		0.79 0.46 -0.46 C0210
102 C0174 MST_2370.2 - - - 0.78 0.47 -0.46
103 C0258 Tryptophan amide (NH3+) D,L-Tryptophan amide (NH3+) - - 0.78 0.42 -0.4
104 C0168 MST_2023.2 - - - 0.77 0.47 -0.45
105 C0098 Glucose D-Glucose alpha-D-glucose; beta-D-glucose trehalose degradation II (trehalase),
indole glucosinolate breakdown (active in intact plant cell),
coumarin biosynthesis (via 2-coumarate),
glucosinolate biosynthesis from tryptophan,
sinapate ester biosynthesis,
GDP-glucose biosynthesis,
coniferin metabolism,
melibiose degradation,
indole glucosinolate breakdown (insect chewing induced) 		0.76 0.32 -0.32 C0098
106 C0252 Threonic acid D,L-Threonic acid L-Threonate ascorbic acid degradation 0.7 0.47 -0.47 C0252
107 C0141 Malic acid D,L-Malic acid (RS)-Malate sinapate ester biosynthesis,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle variation III (eukaryotic),
glyoxylate cycle,
aspartate degradation II,
TCA cycle variation V (plant),
gluconeogenesis I,
glycolate and glyoxylate degradation II 		0.67 0.3 -0.31 C0141
108 C0016 S-Adenosylmethionine S-Adenosyl-L-methionine S-Adenosyl-L-methionine ethylene biosynthesis I (plants),
scopoletin biosynthesis,
quercetinsulphates biosynthesis,
siroheme biosynthesis,
gibberellin inactivation II (methylation),
suberin biosynthesis,
volatile benzenoid biosynthesis I (ester formation),
S-adenosyl-L-methionine cycle II,
methylhalides biosynthesis (plants),
S-methylmethionine cycle,
ubiquinol-9 biosynthesis (eukaryotic),
nicotianamine biosynthesis,
methionine biosynthesis II,
spermine biosynthesis,
choline biosynthesis II,
diphthamide biosynthesis,
homogalacturonan biosynthesis,
phosphatidylcholine biosynthesis II,
methylquercetin biosynthesis,
plastoquinol biosynthesis,
chlorophyllide a biosynthesis I,
ferulate and sinapate biosynthesis,
ubiquinol-10 biosynthesis (eukaryotic),
phenylpropanoid biosynthesis,
free phenylpropanoid acid biosynthesis,
seleno-amino acid detoxification and volatilization I,
plant sterol biosynthesis,
lipoate biosynthesis and incorporation I,
methyl indole-3-acetate interconversion,
cyclopropane and cyclopropene fatty acid biosynthesis,
spermidine biosynthesis I,
thiamine biosynthesis II,
methionine salvage pathway,
spermidine hydroxycinnamic acid conjugates biosynthesis,
simple coumarins biosynthesis,
phosphatidylcholine biosynthesis IV,
glutathione-mediated detoxification II,
S-adenosyl-L-methionine biosynthesis,
methionine degradation I (to homocysteine),
phosphatidylcholine biosynthesis III,
phylloquinol biosynthesis,
choline biosynthesis I,
biotin biosynthesis II,
vitamin E biosynthesis 		0.66 0.45 -0.47 C0016