C0141 : Malic acid
Query Information
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ID C0141
Compound name Malic acid
External link   http://pmn.plantcyc.org/ARA/NEW-IMAGE?type=COMPOUND&object=MAL
Pathway Information sinapate ester biosynthesis,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle variation III (eukaryotic),
glyoxylate cycle,
aspartate degradation II,
TCA cycle variation V (plant),
gluconeogenesis I,
glycolate and glyoxylate degradation II
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT3G60630 GRAS family transcription factor ARABIDOPSIS THALIANA HAIRY
MERISTEM 2, HAIRY MERISTEM 2, LOST
MERISTEMS 2		 -0.77 0.34 -0.33
2 AT4G35720 Arabidopsis protein of unknown function (DUF241) -0.71 0.32 -0.28
3 AT1G19300 Nucleotide-diphospho-sugar transferases superfamily protein ATGATL1,
GALACTURONOSYLTRANSFERASE-LIKE 1,
GAOLAOZHUANGREN 1, PARVUS		 0.71 0.31 -0.32
4 AT1G04010 phospholipid sterol acyl transferase 1 ATPSAT1, phospholipid sterol acyl
transferase 1		 0.71 0.31 -0.31
5 AT5G43700 AUX/IAA transcriptional regulator family protein AUXIN INDUCIBLE 2-11,
indole-3-acetic acid inducible 4		 -0.69 0.32 -0.32
6 AT2G18730 diacylglycerol kinase 3 ATDGK3, diacylglycerol kinase 3 0.69 0.31 -0.33
7 AT5G48960 HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase 0.68 0.31 -0.32
8 AT1G75040 pathogenesis-related gene 5 PR-5, pathogenesis-related gene 5 0.67 0.3 -0.32
9 AT2G39890 proline transporter 1 PROLINE TRANSPORTER 1, proline
transporter 1		 0.67 0.34 -0.32
10 AT5G11930 Thioredoxin superfamily protein 0.67 0.33 -0.3
11 AT1G62770 Plant invertase/pectin methylesterase inhibitor superfamily
protein		 -0.67 0.3 -0.33
12 AT2G38740 Haloacid dehalogenase-like hydrolase (HAD) superfamily
protein		 0.66 0.33 -0.31
13 AT3G16770 ethylene-responsive element binding protein ethylene-responsive element
binding protein,
ethylene-responsive element
binding protein, ETHYLENE RESPONSE
FACTOR 72, RELATED TO AP2 3		 -0.65 0.29 -0.31
14 AT4G07580 transposable element gene 0.65 0.31 -0.3
15 AT2G23180 cytochrome P450, family 96, subfamily A, polypeptide 1 cytochrome P450, family 96,
subfamily A, polypeptide 1		 -0.64 0.34 -0.34
16 AT5G53460 NADH-dependent glutamate synthase 1 NADH-dependent glutamate synthase
1		 -0.64 0.32 -0.3
17 AT3G29370 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT5G39240.1); Has 16 Blast hits
to 16 proteins in 5 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 16; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 P1R3 -0.64 0.35 -0.3
18 AT4G01080 TRICHOME BIREFRINGENCE-LIKE 26 TRICHOME BIREFRINGENCE-LIKE 26 0.64 0.31 -0.31
19 AT5G44210 erf domain protein 9 ERF DOMAIN PROTEIN- 9, ERF DOMAIN
PROTEIN 9, erf domain protein 9		 -0.63 0.33 -0.31
20 AT2G33290 SU(VAR)3-9 homolog 2 ATSUVH2, SET DOMAIN-CONTAINING
PROTEIN 3, SU(VAR)3-9 homolog 2		 -0.63 0.29 -0.32
21 AT4G11890 Protein kinase superfamily protein 0.63 0.32 -0.33
22 AT5G43520 Cysteine/Histidine-rich C1 domain family protein -0.63 0.33 -0.29
23 AT1G62430 CDP-diacylglycerol synthase 1 CDP-diacylglycerol synthase 1,
CDP-diacylglycerol synthase 1		 0.63 0.31 -0.33
24 AT5G62280 Protein of unknown function (DUF1442) -0.63 0.33 -0.31
25 AT4G38620 myb domain protein 4 myb domain protein 4, myb domain
protein 4		 0.62 0.33 -0.32
26 AT1G79260 CONTAINS InterPro DOMAIN/s: Domain of unknown function
DUF1794 (InterPro:IPR014878); Has 30201 Blast hits to 17322
proteins in 780 species: Archae - 12; Bacteria - 1396;
Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0;
Other Eukaryotes - 2996 (source: NCBI BLink).		 -0.62 0.31 -0.34
27 AT5G46760 Basic helix-loop-helix (bHLH) DNA-binding family protein MYC3 0.62 0.32 -0.31
28 AT3G49960 Peroxidase superfamily protein -0.62 0.31 -0.32
29 AT1G56560 Plant neutral invertase family protein alkaline/neutral invertase A 0.61 0.31 -0.32
30 AT1G21710 8-oxoguanine-DNA glycosylase 1 ARABIDOPSIS 8-OXOGUANINE-DNA
GLYCOSYLASE 1, 8-oxoguanine-DNA
glycosylase 1		 -0.61 0.31 -0.31
31 AT1G68120 basic pentacysteine 3 ATBPC3, basic pentacysteine 3 -0.61 0.31 -0.31
32 AT1G52020 transposable element gene -0.61 0.32 -0.3
33 AT2G40840 disproportionating enzyme 2 disproportionating enzyme 2 0.61 0.32 -0.31
34 AT5G54040 Cysteine/Histidine-rich C1 domain family protein -0.6 0.31 -0.32
35 AT5G08500 Transmembrane CLPTM1 family protein -0.6 0.31 -0.33
36 AT2G39370 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT2G37380.1); Has 184 Blast hits
to 178 proteins in 53 species: Archae - 0; Bacteria - 58;
Metazoa - 9; Fungi - 0; Plants - 103; Viruses - 0; Other
Eukaryotes - 14 (source: NCBI BLink).		 MEMBRANE-ASSOCIATED KINASE
REGULATOR 4		 -0.59 0.31 -0.3
37 AT1G78090 trehalose-6-phosphate phosphatase Arabidopsis thaliana
trehalose-6-phosphate phosphatase
B, trehalose-6-phosphate
phosphatase B		 -0.58 0.3 -0.32
38 AT1G02070 unknown protein; BEST Arabidopsis thaliana protein match
is: unknown protein (TAIR:AT3G60520.1); Has 98 Blast hits
to 98 proteins in 13 species: Archae - 0; Bacteria - 0;
Metazoa - 0; Fungi - 0; Plants - 98; Viruses - 0; Other
Eukaryotes - 0 (source: NCBI BLink).		 -0.58 0.33 -0.33
39 AT4G26010 Peroxidase superfamily protein -0.58 0.32 -0.29
40 AT3G54220 GRAS family transcription factor SCARECROW, SHOOT GRAVITROPISM 1 -0.58 0.33 -0.31
41 AT5G10100 Haloacid dehalogenase-like hydrolase (HAD) superfamily
protein		 trehalose-6-phosphate phosphatase
I		 -0.57 0.31 -0.3
42 AT1G09280 CONTAINS InterPro DOMAIN/s: Rhodanese-like
(InterPro:IPR001763), Serine hydrolase
(InterPro:IPR005645); BEST Arabidopsis thaliana protein
match is: Rhodanese/Cell cycle control phosphatase
superfamily protein (TAIR:AT2G40760.1); Has 5925 Blast hits
to 5912 proteins in 1592 species: Archae - 0; Bacteria -
2946; Metazoa - 156; Fungi - 408; Plants - 229; Viruses -
0; Other Eukaryotes - 2186 (source: NCBI BLink).		 -0.57 0.33 -0.3
43 AT4G17080 Histone H3 K4-specific methyltransferase SET7/9 family
protein		 -0.56 0.3 -0.31
44 AT5G35190 proline-rich extensin-like family protein extensin 13 -0.56 0.29 -0.31
45 AT5G57540 xyloglucan endotransglucosylase/hydrolase 13 AtXTH13, xyloglucan
endotransglucosylase/hydrolase 13		 -0.56 0.33 -0.34
46 AT5G15720 GDSL-motif lipase 7 GDSL-motif lipase 7 -0.56 0.32 -0.32
47 AT1G65930 cytosolic NADP+-dependent isocitrate dehydrogenase cytosolic NADP+-dependent
isocitrate dehydrogenase		 -0.56 0.31 -0.32
48 AT1G77760 nitrate reductase 1 GNR1, nitrate reductase 1, NITRATE
REDUCTASE 1		 -0.56 0.32 -0.32
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
49 C0141 Malic acid D,L-Malic acid (RS)-Malate sinapate ester biosynthesis,
superpathway of glyoxylate cycle and fatty acid degradation,
TCA cycle variation III (eukaryotic),
glyoxylate cycle,
aspartate degradation II,
TCA cycle variation V (plant),
gluconeogenesis I,
glycolate and glyoxylate degradation II 		1 0.31 -0.32 C0141
50 C0158 MST_1480.5 - - - 0.84 0.43 -0.47
51 C0174 MST_2370.2 - - - 0.74 0.43 -0.43
52 C0051 Aconitic acid cis-Aconitic acid cis-Aconitate glutamine biosynthesis III,
TCA cycle variation V (plant),
glyoxylate cycle,
TCA cycle variation III (eukaryotic) 		0.69 0.44 -0.44 C0051
53 C0009 myo-Inositol - myo-Inositol stachyose biosynthesis,
UDP-D-glucuronate biosynthesis (from myo-inositol),
1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza),
D-myo-inositol (1,4,5)-trisphosphate degradation,
galactosylcyclitol biosynthesis,
D-myo-inositol (1,4,5)-trisphosphate biosynthesis,
phytate degradation I,
myo-inositol biosynthesis,
ajugose biosynthesis I (galactinol-dependent),
phospholipid biosynthesis II 		0.68 0.48 -0.47 C0009
54 C0106 Glyceric acid D,L-Glyceric acid Glycerate photorespiration 0.67 0.33 -0.3 C0106
55 C0092 Fumaric acid - Fumarate citrulline-nitric oxide cycle,
succinate + a ubiquinone -> a ubiquinol + fumarate,
superpathway of glyoxylate cycle and fatty acid degradation,
tyrosine degradation I,
aerobic respiration (alternative oxidase pathway),
inosine-5'-phosphate biosynthesis II,
arginine biosynthesis I,
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
purine nucleotides de novo biosynthesis II,
arginine biosynthesis II (acetyl cycle),
urea cycle,
aerobic respiration (cytochrome c) 		0.67 0.3 -0.3 C0092
56 C0098 Glucose D-Glucose alpha-D-glucose; beta-D-glucose trehalose degradation II (trehalase),
indole glucosinolate breakdown (active in intact plant cell),
coumarin biosynthesis (via 2-coumarate),
glucosinolate biosynthesis from tryptophan,
sinapate ester biosynthesis,
GDP-glucose biosynthesis,
coniferin metabolism,
melibiose degradation,
indole glucosinolate breakdown (insect chewing induced) 		0.66 0.31 -0.33 C0098
57 C0184 MST_3110.4 - - - 0.65 0.46 -0.47
58 C0168 MST_2023.2 - - - 0.61 0.43 -0.45