ID | C0104 |
Compound name | Glutathione |
External link | http://pmn.plantcyc.org/ARA/NEW-IMAGE?type=COMPOUND&object=GLUTATHIONE |
Pathway Information | glucosinolate biosynthesis from tryptophan, glutathione redox reactions I, glutathione degradation, gamma-glutamyl cycle (plant pathway), indole glucosinolate breakdown (active in intact plant cell), selenate reduction, glutathione redox reactions II, glucosinolate biosynthesis from trihomomethionine, ascorbate glutathione cycle, glucosinolate biosynthesis from pentahomomethionine, camalexin biosynthesis, glucosinolate biosynthesis from homomethionine, glucosinolate biosynthesis from phenylalanine, methylglyoxal degradation I, sulfate reduction II (assimilatory), glucosinolate biosynthesis from dihomomethionine, indole glucosinolate breakdown (insect chewing induced), glutathione biosynthesis, formaldehyde oxidation II (glutathione-dependent), glutathione-mediated detoxification II, glucosinolate biosynthesis from tetrahomomethionine, glucosinolate biosynthesis from hexahomomethionine, gamma-glutamyl cycle |
Gene Code | Description / Information | Gene name | Correlation | link | ||||
---|---|---|---|---|---|---|---|---|
pcc | 2.5% | 97.5% | PPI | |||||
1 | AT1G19200 | Protein of unknown function (DUF581) | 0.61 | 0.32 | -0.33 | |||
2 | AT1G61930 | Protein of unknown function, DUF584 | -0.61 | 0.34 | -0.34 | |||
3 | AT1G60750 | NAD(P)-linked oxidoreductase superfamily protein | 0.61 | 0.29 | -0.3 | |||
4 | AT4G13980 | winged-helix DNA-binding transcription factor family protein |
AT-HSFA5, HEAT SHOCK TRANSCRIPTION FACTOR A5 |
0.61 | 0.31 | -0.32 | ||
5 | AT2G20150 | unknown protein; Has 5 Blast hits to 5 proteins in 1 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). |
-0.61 | 0.28 | -0.32 | |||
6 | AT5G11890 | FUNCTIONS IN: molecular_function unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 6 growth stages; BEST Arabidopsis thaliana protein match is: Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family (TAIR:AT1G17620.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). |
EMBRYO DEFECTIVE 3135 | -0.61 | 0.3 | -0.33 | ||
7 | AT1G22080 | Cysteine proteinases superfamily protein | 0.6 | 0.32 | -0.31 | |||
8 | AT5G61320 | cytochrome P450, family 89, subfamily A, polypeptide 3 | cytochrome P450, family 89, subfamily A, polypeptide 3 |
0.6 | 0.32 | -0.33 | ||
9 | AT1G37060 | transposable element gene | -0.59 | 0.33 | -0.31 | |||
10 | AT2G30380 | Plant protein of unknown function (DUF641) | -0.59 | 0.32 | -0.31 | |||
11 | AT1G19890 | male-gamete-specific histone H3 | MALE-GAMETE-SPECIFIC HISTONE H3, male-gamete-specific histone H3 |
0.57 | 0.32 | -0.31 | ||
12 | AT1G51915 | cryptdin protein-related | -0.57 | 0.32 | -0.34 | |||
13 | AT1G61070 | low-molecular-weight cysteine-rich 66 | low-molecular-weight cysteine-rich 66, PLANT DEFENSIN 2.4 |
0.57 | 0.29 | -0.33 | ||
14 | AT4G36790 | Major facilitator superfamily protein | 0.56 | 0.31 | -0.32 | |||
15 | AT5G28790 | transposable element gene | -0.56 | 0.31 | -0.33 | |||
16 | AT5G35510 | unknown protein; Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). |
0.54 | 0.31 | -0.31 | |||
17 | AT5G47360 | Tetratricopeptide repeat (TPR)-like superfamily protein | -0.54 | 0.31 | -0.3 | |||
18 | AT3G44630 | Disease resistance protein (TIR-NBS-LRR class) family | -0.54 | 0.29 | -0.32 | |||
19 | AT1G08130 | DNA ligase 1 | DNA ligase 1, DNA ligase 1 | -0.54 | 0.32 | -0.33 | ||
20 | AT5G34830 | unknown protein; Has 19 Blast hits to 19 proteins in 6 species: Archae - 0; Bacteria - 0; Metazoa - 3; Fungi - 0; Plants - 16; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). |
0.54 | 0.32 | -0.34 | |||
21 | AT4G24660 | homeobox protein 22 | HOMEOBOX PROTEIN 22, homeobox protein 22, MATERNAL EFFECT EMBRYO ARREST 68, ZINC FINGER HOMEODOMAIN 2 |
-0.53 | 0.32 | -0.32 | ||
22 | AT1G73700 | MATE efflux family protein | -0.53 | 0.32 | -0.33 | |||
23 | AT5G25880 | NADP-malic enzyme 3 | Arabidopsis thaliana NADP-malic enzyme 3, NADP-malic enzyme 3 |
0.53 | 0.33 | -0.34 | ||
24 | AT4G21090 | MITOCHONDRIAL FERREDOXIN 2 | ARABIDOPSIS MITOCHONDRIAL FERREDOXIN 2, MITOCHONDRIAL FERREDOXIN 2 |
0.53 | 0.32 | -0.33 | ||
25 | AT2G16810 | F-box and associated interaction domains-containing protein | -0.53 | 0.32 | -0.3 | |||
26 | AT1G76880 | Duplicated homeodomain-like superfamily protein | -0.52 | 0.29 | -0.33 | |||
27 | AT4G31630 | Transcriptional factor B3 family protein | 0.51 | 0.32 | -0.3 | |||
28 | AT2G33690 | Late embryogenesis abundant protein, group 6 | -0.51 | 0.32 | -0.3 | |||
29 | AT3G17740 | unknown protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1740 (InterPro:IPR013633); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT3G17712.1); Has 409 Blast hits to 335 proteins in 133 species: Archae - 1; Bacteria - 0; Metazoa - 140; Fungi - 188; Plants - 42; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink). |
-0.5 | 0.31 | -0.31 | |||
30 | AT3G43150 | unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G11010.1); Has 34 Blast hits to 32 proteins in 2 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 34; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). |
-0.5 | 0.32 | -0.32 | |||
31 | AT4G26150 | cytokinin-responsive gata factor 1 | cytokinin-responsive gata factor 1, GATA TRANSCRIPTION FACTOR 22, GNC-LIKE |
-0.49 | 0.3 | -0.31 | ||
32 | AT5G28270 | transposable element gene | -0.49 | 0.33 | -0.3 | |||
33 | AT1G12210 | RPS5-like 1 | RPS5-like 1 | 0.48 | 0.32 | -0.31 | ||
34 | AT1G06070 | Basic-leucine zipper (bZIP) transcription factor family protein |
-0.47 | 0.33 | -0.31 | |||
35 | AT3G27070 | translocase outer membrane 20-1 | translocase outer membrane 20-1 | 0.47 | 0.31 | -0.32 | ||
36 | AT1G17545 | Protein phosphatase 2C family protein | -0.47 | 0.32 | -0.32 | |||
37 | AT3G59790 | MAP kinase 10 | MAP kinase 10, MAP kinase 10 | 0.47 | 0.3 | -0.31 | ||
38 | AT3G03830 | SAUR-like auxin-responsive protein family | 0.47 | 0.31 | -0.3 | |||
39 | AT3G47130 | F-box associated ubiquitination effector family protein | -0.46 | 0.32 | -0.31 | |||
40 | AT2G37010 | non-intrinsic ABC protein 12 | non-intrinsic ABC protein 12, non-intrinsic ABC protein 12 |
-0.46 | 0.3 | -0.33 | ||
41 | AT2G07230 | transposable element gene | 0.46 | 0.33 | -0.31 | |||
42 | AT5G28080 | Protein kinase superfamily protein | WNK9 | 0.46 | 0.32 | -0.34 |
CID | Metabolite name | Pathway Information | Correlation | link | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Compound name | Stereochemistry | Aracyc name | pcc | 2.5% | 97.5% | PPI | ||||
43 | C0104 | Glutathione | - | Glutathione | glucosinolate biosynthesis from tryptophan, glutathione redox reactions I, glutathione degradation, gamma-glutamyl cycle (plant pathway), indole glucosinolate breakdown (active in intact plant cell), selenate reduction, glutathione redox reactions II, glucosinolate biosynthesis from trihomomethionine, ascorbate glutathione cycle, glucosinolate biosynthesis from pentahomomethionine, camalexin biosynthesis, glucosinolate biosynthesis from homomethionine, glucosinolate biosynthesis from phenylalanine, methylglyoxal degradation I, sulfate reduction II (assimilatory), glucosinolate biosynthesis from dihomomethionine, indole glucosinolate breakdown (insect chewing induced), glutathione biosynthesis, formaldehyde oxidation II (glutathione-dependent), glutathione-mediated detoxification II, glucosinolate biosynthesis from tetrahomomethionine, glucosinolate biosynthesis from hexahomomethionine, gamma-glutamyl cycle |
1 | 0.33 | -0.33 | ||
44 | C0073 | Cysteine | L-Cysteine | L-Cysteine | alanine biosynthesis III, cysteine biosynthesis I, gamma-glutamyl cycle (plant pathway), farnesylcysteine salvage pathway, molybdenum cofactor biosynthesis, thiamine biosynthesis II, cyanide detoxification II, indole glucosinolate breakdown (insect chewing induced), glutathione degradation, glutathione biosynthesis, molybdenum cofactor biosynthesis II (eukaryotes), cyanide degradation, homocysteine and cysteine interconversion, methionine biosynthesis II, tRNA charging, gamma-glutamyl cycle, coenzyme A biosynthesis |
0.94 | 0.47 | -0.45 | ||
45 | C0186 | NAD | - | NAD+ | ammonia assimilation cycle II, aspartate degradation II, adenosine nucleotides degradation I, plant sterol biosynthesis II, UDP-D-xylose and UDP-D-glucuronate biosynthesis, NAD biosynthesis I (from aspartate), ethanol degradation IV (peroxisomal), abscisic acid biosynthesis, palmitate biosynthesis II (bacteria and plants), zeaxanthin biosynthesis, sucrose degradation to ethanol and lactate (anaerobic), glutamate degradation IV, stearate biosynthesis II (plants), guanosine nucleotides degradation II, glutamate degradation I, mannitol degradation II, glycerol-3-phosphate shuttle, 2-ketoglutarate dehydrogenase complex, arginine degradation I (arginase pathway), aerobic respiration (alternative oxidase pathway), branched-chain alpha-keto acid dehydrogenase complex, 4-aminobutyrate degradation IV, glycolysis I, glycine cleavage complex, lysine degradation II, fatty acid beta-oxidation II (core pathway), nitrate reduction II (assimilatory), TCA cycle variation V (plant), leucine degradation I, thiamine biosynthesis II, acetaldehyde biosynthesis I, sorbitol degradation I, glutamine biosynthesis III, aerobic respiration (cytochrome c), ethanol degradation I, ascorbate biosynthesis I (L-galactose pathway), glycolysis IV (plant cytosol), benzoate biosynthesis II (CoA-independent, non-beta-oxidative), siroheme biosynthesis, TCA cycle variation III (eukaryotic), isoleucine degradation I, pyridine nucleotide cycling (plants), tyrosine biosynthesis I, gluconeogenesis I, glycine betaine biosynthesis III (plants), traumatin and (Z)-3-hexen-1-yl acetate biosynthesis, NAD/NADH phosphorylation and dephosphorylation, guanosine nucleotides degradation I, purine nucleotides de novo biosynthesis II, acetyl-CoA biosynthesis (from pyruvate), serine biosynthesis, photorespiration, histidine biosynthesis, glyoxylate cycle, jasmonic acid biosynthesis, alanine degradation II (to D-lactate), a ubiquinone + NADH + H+ -> a ubiquinol + NAD+, putrescine degradation IV, brassinosteroid biosynthesis III, fatty acid elongation -- saturated, pyruvate fermentation to ethanol II, beta-alanine biosynthesis II, 4-hydroxybenzoate biosynthesis V, plant sterol biosynthesis, urate biosynthesis/inosine 5'-phosphate degradation, phenylalanine degradation III, glutamate biosynthesis IV, leucine biosynthesis, fatty acid alpha-oxidation, a ubiquinone + NADH + H+ -> NAD+ + a ubiquinol, Fe(III)-reduction and Fe(II) transport, purine nucleotide metabolism (phosphotransfer and nucleotide modification), phenylethanol biosynthesis, pyruvate fermentation to lactate, superpathway of glyoxylate cycle and fatty acid degradation, fatty acid omega-oxidation, galactose degradation III, ethanol degradation II (cytosol), sucrose biosynthesis I, valine degradation I, folate transformations II |
0.88 | 0.47 | -0.45 | ||
46 | C0099 | Glucose-1-phosphate | α,β-D-Glucose-1-phosphate | α-D-Glucose-1-phosphate; β-D-Glucose-1-phosphate | galactose degradation I (Leloir pathway) | 0.8 | 0.43 | -0.45 | ||
47 | C0088 | FAD | - | FAD | cytokinins degradation, lysine degradation II, valine degradation I, isoleucine degradation I, flavin biosynthesis I (bacteria and plants) |
0.78 | 0.43 | -0.43 | ||
48 | C0026 | 2-Hydroxyisobutyric acid | - | - | β oxidation | 0.78 | 0.46 | -0.45 | ||
49 | C0261 | UDP-glucose | - | UDP-D-glucose | quercetin glucoside biosynthesis (Arabidopsis), abscisic acid glucose ester biosynthesis, anthocyanin biosynthesis (delphinidin 3-O-glucoside), UDP-glucose biosynthesis (from sucrose), 2,4,6-trinitrotoluene degradation, galactose degradation I (Leloir pathway), cytokinins-O-glucoside biosynthesis, trehalose biosynthesis I, dolichyl-diphosphooligosaccharide biosynthesis, phenolic malonylglucosides biosynthesis, callose biosynthesis, superpathway of anthocyanin biosynthesis (from cyanidin and cyanidin 3-O-glucoside), glucosinolate biosynthesis from hexahomomethionine, coniferin metabolism, glucosinolate biosynthesis from phenylalanine, xyloglucan biosynthesis, glucosinolate biosynthesis from pentahomomethionine, anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside), glucosinolate biosynthesis from dihomomethionine, cellulose biosynthesis, sinapate ester biosynthesis, superpathway of IAA conjugate biosynthesis, salicylate glucosides biosynthesis IV, sucrose biosynthesis I, glucosinolate biosynthesis from trihomomethionine, tetrahydrofolate biosynthesis II, sucrose degradation III, UDP-D-xylose and UDP-D-glucuronate biosynthesis, coumarin biosynthesis (via 2-coumarate), superpathway of sucrose and starch metabolism I (non-photosynthetic tissue), monolignol glucosides biosynthesis, glucosinolate biosynthesis from homomethionine, kaempferol glucoside biosynthesis (Arabidopsis), salicylate glucosides biosynthesis III, cytokinins 7-N-glucoside biosynthesis, galactose degradation III, cytokinins 9-N-glucoside biosynthesis, glucosinolate biosynthesis from tryptophan, UDP-galactose biosynthesis, salicylate glucosides biosynthesis II, stachyose degradation, superpathway of sucrose and starch metabolism II (photosynthetic tissue), UDP-glucose biosynthesis (from glucose 6-phosphate), sphingolipid biosynthesis (plants), glucosinolate biosynthesis from tetrahomomethionine, galactose degradation II, UDP-L-rhamnose biosynthesis |
0.78 | 0.43 | -0.43 | ||
50 | C0149 | Mevalonolactone | D,L-Mevalonolactone | - | terpenoid biosynthesis | 0.78 | 0.43 | -0.46 | ||
51 | C0262 | UDP-glucuronic acid | - | UDP-D-glucuronate | xylan biosynthesis, UDP-D-glucuronate biosynthesis (from myo-inositol), UDP-D-galacturonate biosynthesis I (from UDP-D-glucuronate), UDP-D-apiose biosynthesis (from UDP-D-glucuronate), galactose degradation III, UDP-D-xylose and UDP-D-glucuronate biosynthesis |
0.76 | 0.43 | -0.46 | ||
52 | C0075 | dGDP | - | dGDP | purine nucleotide metabolism (phosphotransfer and nucleotide modification) | 0.74 | 0.44 | -0.44 | ||
53 | C0027 | 2-Oxoglutaric acid | - | α-Ketoglutarate | gibberellin biosynthesis III (early C-13 hydroxylation), leucopelargonidin and leucocyanidin biosynthesis, aspartate degradation II, ornithine biosynthesis, isoleucine biosynthesis I (from threonine), pantothenate biosynthesis, phenylalanine degradation III, flavonol biosynthesis, lysine biosynthesis VI, luteolin biosynthesis, ammonia assimilation cycle II, serine biosynthesis, flavonoid biosynthesis, glutamate biosynthesis V, aspartate biosynthesis, glutamate degradation I, gibberellin inactivation I (2beta-hydroxylation), alanine degradation III, photorespiration, valine biosynthesis, glycine biosynthesis, arginine biosynthesis II (acetyl cycle), arginine degradation I (arginase pathway), gibberellin biosynthesis II (early C-3 hydroxylation), leucine biosynthesis, glutamate biosynthesis IV, tyrosine biosynthesis II, proline biosynthesis III, citrulline biosynthesis, anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside), L-Ndelta-acetylornithine biosynthesis, isoleucine degradation I, alanine biosynthesis II, tyrosine biosynthesis I, TCA cycle variation III (eukaryotic), leucine degradation I, alanine degradation II (to D-lactate), TCA cycle variation V (plant), arginine degradation VI (arginase 2 pathway), valine degradation I, gibberellin biosynthesis I (non C-3, non C-13 hydroxylation), 1,4-dihydroxy-2-naphthoate biosynthesis II (plants), 2-ketoglutarate dehydrogenase complex, glutamate degradation IV, tyrosine degradation I, anthocyanin biosynthesis (delphinidin 3-O-glucoside), IAA biosynthesis I, phenylalanine biosynthesis II, lysine degradation II, scopoletin biosynthesis, 4-hydroxyphenylpyruvate biosynthesis, histidine biosynthesis, glutamine biosynthesis III, leucodelphinidin biosynthesis |
0.72 | 0.47 | -0.46 | ||
54 | C0091 | Fructose-1,6-bisphosphate | D-Fructose-1,6-bisphosphate | Fructose-1,6-bisphosphate | gluconeogenesis I, Calvin-Benson-Bassham cycle, glycolysis IV (plant cytosol), glycolysis I, CA1P biosynthesis, sucrose biosynthesis I |
0.71 | 0.46 | -0.43 | ||
55 | C0239 | Spermidine | - | Spermidine | spermine biosynthesis, spermine and spermidine degradation III, beta-alanine biosynthesis I, hypusine biosynthesis, spermidine hydroxycinnamic acid conjugates biosynthesis, spermidine biosynthesis I |
0.69 | 0.44 | -0.49 | ||
56 | C0087 | Erythrose-4-phosphate | D-Erythrose-4-phosphate | D-Erythrose-4-phosphate | Rubisco shunt, pentose phosphate pathway (non-oxidative branch), chorismate biosynthesis, Calvin-Benson-Bassham cycle |
0.68 | 0.47 | -0.45 | ||
57 | C0030 | 3-Methylsulfinyl-n-propylglucosinolate | - | 3-Methylsulfinylpropyl-glucosinolate | glucosinolate biosynthesis from homomethionine | 0.66 | 0.45 | -0.45 | ||
58 | C0011 | N-Acetyl-glutamic acid | N-Acetyl-D,L-glutamic acid | N-Acetyl-L-glutamate | arginine biosynthesis II (acetyl cycle), ornithine biosynthesis |
0.65 | 0.43 | -0.44 | ||
59 | C0006 | β-Homothreonine | L-β-Homothreonine | - | - | 0.63 | 0.43 | -0.45 | ||
60 | C0112 | Histidine | L-Histidine | L-Histidine | tRNA charging, histidine biosynthesis |
0.53 | 0.32 | -0.32 |