C0243 : Succinic acid
Query Information
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ID C0243
Compound name Succinic acid
External link   http://pmn.plantcyc.org/ARA/NEW-IMAGE?type=COMPOUND&object=SUC
Pathway Information flavonol biosynthesis,
glyoxylate cycle,
gibberellin biosynthesis III (early C-13 hydroxylation),
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
aerobic respiration (alternative oxidase pathway),
gibberellin inactivation I (2beta-hydroxylation),
4-aminobutyrate degradation IV,
luteolin biosynthesis,
anthocyanin biosynthesis (delphinidin 3-O-glucoside),
leucodelphinidin biosynthesis,
glutamate degradation IV,
gibberellin biosynthesis I (non C-3, non C-13 hydroxylation),
succinate + a ubiquinone -> a ubiquinol + fumarate,
gibberellin biosynthesis II (early C-3 hydroxylation),
flavonoid biosynthesis,
superpathway of glyoxylate cycle and fatty acid degradation,
aerobic respiration (cytochrome c),
leucopelargonidin and leucocyanidin biosynthesis,
anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside),
scopoletin biosynthesis
Gene information
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  Gene Code Description / Information Gene name Correlation link
pcc 2.5% 97.5% PPI
1 AT1G77260 S-adenosyl-L-methionine-dependent methyltransferases
superfamily protein		 0.69 0.31 -0.31
2 AT3G52170 DNA binding -0.68 0.3 -0.29
3 AT2G32080 purin-rich alpha 1 purin-rich alpha 1 0.68 0.31 -0.31
4 AT1G11930 Predicted pyridoxal phosphate-dependent enzyme, YBL036C
type		 0.67 0.33 -0.33
5 AT5G08260 serine carboxypeptidase-like 35 serine carboxypeptidase-like 35 -0.65 0.35 -0.33
6 AT5G55250 IAA carboxylmethyltransferase 1 AtIAMT1, IAA
carboxylmethyltransferase 1		 -0.65 0.34 -0.33
7 AT3G22400 PLAT/LH2 domain-containing lipoxygenase family protein Arabidopsis thaliana lipoxygenase
5, LOX5		 0.65 0.32 -0.31
8 AT5G46270 Disease resistance protein (TIR-NBS-LRR class) family -0.64 0.31 -0.31
9 AT1G56710 Pectin lyase-like superfamily protein 0.64 0.32 -0.3
10 AT4G01210 glycosyl transferase family 1 protein 0.64 0.32 -0.33
11 AT5G67210 Protein of unknown function (DUF579) IRX15-LIKE 0.62 0.32 -0.34
12 AT1G14820 Sec14p-like phosphatidylinositol transfer family protein -0.61 0.33 -0.33
13 AT1G55520 TATA binding protein 2 A. THALIANA TATA BINDING PROTEIN
2, TATA binding protein 2		 0.61 0.32 -0.3
14 AT3G10700 galacturonic acid kinase galacturonic acid kinase -0.61 0.33 -0.31
15 AT5G01660 CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch,
beta-propeller (InterPro:IPR011043), Kelch repeat type 1
(InterPro:IPR006652), Development/cell death domain
(InterPro:IPR013989), Kelch related (InterPro:IPR013089),
Kelch-type beta propeller (InterPro:IPR015915); BEST
Arabidopsis thaliana protein match is: DCD (Development and
Cell Death) domain protein (TAIR:AT3G11000.1); Has 16133
Blast hits to 7053 proteins in 482 species: Archae - 40;
Bacteria - 1227; Metazoa - 10756; Fungi - 311; Plants -
1896; Viruses - 673; Other Eukaryotes - 1230 (source: NCBI
BLink).		 -0.6 0.3 -0.32
16 AT2G42160 zinc finger (ubiquitin-hydrolase) domain-containing protein BRAP2 RING ZnF UBP
domain-containing protein 1		 0.6 0.32 -0.33
17 AT5G46760 Basic helix-loop-helix (bHLH) DNA-binding family protein MYC3 0.6 0.32 -0.32
18 AT1G72140 Major facilitator superfamily protein 0.6 0.32 -0.31
19 AT2G47010 unknown protein; FUNCTIONS IN: molecular_function unknown;
INVOLVED IN: biological_process unknown; LOCATED IN:
endomembrane system; EXPRESSED IN: 17 plant structures;
EXPRESSED DURING: 10 growth stages; BEST Arabidopsis
thaliana protein match is: unknown protein
(TAIR:AT1G17030.1); Has 72 Blast hits to 72 proteins in 13
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 71; Viruses - 0; Other Eukaryotes - 1 (source:
NCBI BLink).		 -0.59 0.32 -0.31
20 AT5G25120 ytochrome p450, family 71, subfamily B, polypeptide 11 ytochrome p450, family 71,
subfamily B, polypeptide 11		 -0.59 0.32 -0.31
21 AT3G19540 Protein of unknown function (DUF620) -0.58 0.31 -0.32
22 AT3G27520 unknown protein; Has 28 Blast hits to 28 proteins in 10
species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0;
Plants - 28; Viruses - 0; Other Eukaryotes - 0 (source:
NCBI BLink).		 -0.58 0.34 -0.33
23 AT2G38530 lipid transfer protein 2 cell growth defect factor-3, LP2,
lipid transfer protein 2		 -0.57 0.3 -0.3
24 AT1G21640 NAD kinase 2 NAD KINASE 2, NAD kinase 2 0.57 0.29 -0.31
25 AT5G60790 ABC transporter family protein ATP-binding cassette F1,
ARABIDOPSIS THALIANA GENERAL
CONTROL NON-REPRESSIBLE 1, GENERAL
CONTROL NON-REPRESSIBLE 1		 -0.57 0.33 -0.32
26 AT1G74650 myb domain protein 31 ARABIDOPSIS THALIANA MYB DOMAIN
PROTEIN 31, ATY13, myb domain
protein 31		 -0.57 0.33 -0.31
27 AT2G04520 Nucleic acid-binding, OB-fold-like protein -0.57 0.33 -0.32
28 AT1G48800 Terpenoid cyclases/Protein prenyltransferases superfamily
protein		 -0.57 0.33 -0.31
29 AT5G40430 myb domain protein 22 myb domain protein 22, myb domain
protein 22		 -0.57 0.3 -0.33
30 AT1G37057 transposable element gene -0.56 0.32 -0.31
31 AT5G39260 expansin A21 ATEXP21, expansin A21, ATHEXP
ALPHA 1.20, EXPANSIN 21, expansin
A21		 -0.56 0.34 -0.32
32 AT1G34650 homeodomain GLABROUS 10 homeodomain GLABROUS 10 -0.55 0.3 -0.31
33 AT3G43660 Vacuolar iron transporter (VIT) family protein -0.55 0.31 -0.32
34 AT1G13110 cytochrome P450, family 71 subfamily B, polypeptide 7 cytochrome P450, family 71
subfamily B, polypeptide 7		 -0.55 0.32 -0.32
35 AT1G55915 zinc ion binding -0.54 0.32 -0.3
36 AT2G41010 calmodulin (CAM)-binding protein of 25 kDa calmodulin (CAM)-binding protein
of 25 kDa, calmodulin
(CAM)-binding protein of 25 kDa		 -0.54 0.37 -0.32
37 AT5G65630 global transcription factor group E7 global transcription factor group
E7		 -0.54 0.31 -0.34
38 AT5G60630 FUNCTIONS IN: molecular_function unknown; INVOLVED IN:
biological_process unknown; LOCATED IN: endomembrane
system; EXPRESSED IN: 17 plant structures; EXPRESSED
DURING: 6 growth stages; BEST Arabidopsis thaliana protein
match is: hydroxyproline-rich glycoprotein family protein
(TAIR:AT3G45230.1); Has 1807 Blast hits to 1807 proteins in
277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi
- 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339
(source: NCBI BLink).		 -0.54 0.31 -0.32
39 AT5G48720 x-ray induced transcript 1 X-RAY INDUCED TRANSCRIPT, X-RAY
INDUCED TRANSCRIPT 1		 -0.54 0.3 -0.3
Metabolite information
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  CID Metabolite name Pathway Information Correlation link
Compound name Stereochemistry Aracyc name pcc 2.5% 97.5% PPI
40 C0243 Succinic acid - Succinate flavonol biosynthesis,
glyoxylate cycle,
gibberellin biosynthesis III (early C-13 hydroxylation),
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
aerobic respiration (alternative oxidase pathway),
gibberellin inactivation I (2beta-hydroxylation),
4-aminobutyrate degradation IV,
luteolin biosynthesis,
anthocyanin biosynthesis (delphinidin 3-O-glucoside),
leucodelphinidin biosynthesis,
glutamate degradation IV,
gibberellin biosynthesis I (non C-3, non C-13 hydroxylation),
succinate + a ubiquinone -> a ubiquinol + fumarate,
gibberellin biosynthesis II (early C-3 hydroxylation),
flavonoid biosynthesis,
superpathway of glyoxylate cycle and fatty acid degradation,
aerobic respiration (cytochrome c),
leucopelargonidin and leucocyanidin biosynthesis,
anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside),
scopoletin biosynthesis 		1 0.32 -0.31 C0243
41 C0026 2-Hydroxyisobutyric acid - - β oxidation 0.94 0.46 -0.47
42 C0220 Pyruvic acid - Pyruvate sucrose degradation to ethanol and lactate (anaerobic),
alanine degradation II (to D-lactate),
alanine degradation III,
glutamine biosynthesis III,
pyruvate fermentation to ethanol II,
serine racemization,
methylerythritol phosphate pathway,
1,4-dihydroxy-2-naphthoate biosynthesis II (plants),
valine biosynthesis,
seleno-amino acid biosynthesis,
phenylalanine degradation III,
an electron-transfer-related quinone + D-lactate -> an electron-transfer-related quinol + pyruvate,
tetrahydrofolate biosynthesis II,
methylglyoxal degradation I,
glycolysis I,
tryptophan biosynthesis,
salicylate biosynthesis I,
pyruvate fermentation to lactate,
methionine biosynthesis II,
glutathione-mediated detoxification II,
IAA biosynthesis I,
TCA cycle variation V (plant),
Rubisco shunt,
gluconeogenesis I,
acetaldehyde biosynthesis I,
homocysteine and cysteine interconversion,
glycolysis IV (plant cytosol),
4-aminobutyrate degradation IV,
beta-alanine biosynthesis II,
isoleucine biosynthesis I (from threonine),
glutamate degradation IV,
lysine biosynthesis VI,
acetyl-CoA biosynthesis (from pyruvate),
alanine biosynthesis II 		0.89 0.46 -0.45 C0220
43 C0027 2-Oxoglutaric acid - α-Ketoglutarate gibberellin biosynthesis III (early C-13 hydroxylation),
leucopelargonidin and leucocyanidin biosynthesis,
aspartate degradation II,
ornithine biosynthesis,
isoleucine biosynthesis I (from threonine),
pantothenate biosynthesis,
phenylalanine degradation III,
flavonol biosynthesis,
lysine biosynthesis VI,
luteolin biosynthesis,
ammonia assimilation cycle II,
serine biosynthesis,
flavonoid biosynthesis,
glutamate biosynthesis V,
aspartate biosynthesis,
glutamate degradation I,
gibberellin inactivation I (2beta-hydroxylation),
alanine degradation III,
photorespiration,
valine biosynthesis,
glycine biosynthesis,
arginine biosynthesis II (acetyl cycle),
arginine degradation I (arginase pathway),
gibberellin biosynthesis II (early C-3 hydroxylation),
leucine biosynthesis,
glutamate biosynthesis IV,
tyrosine biosynthesis II,
proline biosynthesis III,
citrulline biosynthesis,
anthocyanin biosynthesis (pelargonidin 3-O-glucoside, cyanidin 3-O-glucoside),
L-Ndelta-acetylornithine biosynthesis,
isoleucine degradation I,
alanine biosynthesis II,
tyrosine biosynthesis I,
TCA cycle variation III (eukaryotic),
leucine degradation I,
alanine degradation II (to D-lactate),
TCA cycle variation V (plant),
arginine degradation VI (arginase 2 pathway),
valine degradation I,
gibberellin biosynthesis I (non C-3, non C-13 hydroxylation),
1,4-dihydroxy-2-naphthoate biosynthesis II (plants),
2-ketoglutarate dehydrogenase complex,
glutamate degradation IV,
tyrosine degradation I,
anthocyanin biosynthesis (delphinidin 3-O-glucoside),
IAA biosynthesis I,
phenylalanine biosynthesis II,
lysine degradation II,
scopoletin biosynthesis,
4-hydroxyphenylpyruvate biosynthesis,
histidine biosynthesis,
glutamine biosynthesis III,
leucodelphinidin biosynthesis 		0.82 0.46 -0.44 C0027
44 C0014 O-Acetylserine O-Acetyl-L-serine O-Acetyl-L-serine cysteine biosynthesis I,
seleno-amino acid biosynthesis 		0.78 0.34 -0.32 C0014
45 C0068 Citric acid - Citrate acetyl-CoA biosynthesis (from citrate),
TCA cycle variation V (plant),
TCA cycle variation III (eukaryotic),
glutamine biosynthesis III,
glyoxylate cycle 		0.77 0.33 -0.31 C0068
46 C0260 Tyrosine L-(-)-Tyrosine L-Tyrosine tyrosine biosynthesis II,
4-hydroxyphenylpyruvate biosynthesis,
tyrosine degradation I,
tyrosine biosynthesis I,
tRNA charging,
hydroxycinnamic acid tyramine amides biosynthesis 		0.77 0.3 -0.31 C0260
47 C0091 Fructose-1,6-bisphosphate D-Fructose-1,6-bisphosphate Fructose-1,6-bisphosphate gluconeogenesis I,
Calvin-Benson-Bassham cycle,
glycolysis IV (plant cytosol),
glycolysis I,
CA1P biosynthesis,
sucrose biosynthesis I 		0.75 0.44 -0.47 C0091
48 C0106 Glyceric acid D,L-Glyceric acid Glycerate photorespiration 0.72 0.31 -0.31 C0106
49 C0257 Tryptophan L-Tryptophan L-Tryptophan glucosinolate biosynthesis from tryptophan,
IAA biosynthesis I,
tryptophan biosynthesis,
camalexin biosynthesis,
tRNA charging 		0.72 0.29 -0.33 C0257
50 C0149 Mevalonolactone D,L-Mevalonolactone - terpenoid biosynthesis 0.72 0.48 -0.44
51 C0241 Stigmasterol 3-O-β-D-glucoside - Stigmasterol 3-O-β-D-glucoside - 0.71 0.53 -0.49 C0241
52 C0054 Agmatine - Agmatine putrescine biosynthesis I,
putrescine biosynthesis II,
superpathway of polyamine biosynthesis 		0.7 0.32 -0.31 C0054
53 C0032 3-Phosphoglyceric acid 3-Phospho-(R)-glyceric acid 3-Phosphoglycerate glycolysis I,
gluconeogenesis I,
Calvin-Benson-Bassham cycle,
sucrose biosynthesis I,
serine biosynthesis,
photorespiration,
Rubisco shunt,
glycolysis IV (plant cytosol) 		0.67 0.43 -0.45 C0032
54 C0170 MST_2128.3 - - - 0.67 0.45 -0.45
55 C0168 MST_2023.2 - - - 0.65 0.47 -0.47
56 C0087 Erythrose-4-phosphate D-Erythrose-4-phosphate D-Erythrose-4-phosphate Rubisco shunt,
pentose phosphate pathway (non-oxidative branch),
chorismate biosynthesis,
Calvin-Benson-Bassham cycle 		0.65 0.43 -0.48 C0087
57 C0053 ADP - ADP phosphatidylcholine biosynthesis I,
mannitol degradation II,
lipid IVA biosynthesis,
stachyose degradation,
Rubisco shunt,
copper transport II,
glycerol degradation IV,
chorismate biosynthesis,
folate polyglutamylation II,
galactose degradation III,
D-myo-inositol (1,4,5)-trisphosphate biosynthesis,
UDP-L-arabinose biosynthesis II (from L-arabinose),
cadmium transport I,
folate polyglutamylation,
coenzyme A biosynthesis,
sulfate activation for sulfonation,
1,4-dihydroxy-2-naphthoate biosynthesis II (plants),
pyrimidine deoxyribonucleotides de novo biosynthesis I,
galactose degradation II,
inosine-5'-phosphate biosynthesis II,
ribose degradation,
acetyl-CoA biosynthesis (from citrate),
inositol pyrophosphates biosynthesis,
fatty acid biosynthesis initiation I,
xylose degradation I,
adenine and adenosine salvage VI,
TCA cycle variation III (eukaryotic),
tetrahydrofolate biosynthesis II,
phosphatidylethanolamine biosynthesis II,
pyridoxal 5'-phosphate salvage pathway,
citrulline biosynthesis,
trans-zeatin biosynthesis,
glutamine biosynthesis I,
arginine biosynthesis II (acetyl cycle),
L-Ndelta-acetylornithine biosynthesis,
mevalonate pathway I,
methionine biosynthesis II,
trehalose degradation II (trehalase),
citrulline degradation,
methionine salvage pathway,
TCA cycle variation V (plant),
chlorophyllide a biosynthesis I,
starch degradation I,
methylerythritol phosphate pathway,
pyridine nucleotide cycling (plants),
ceramide degradation,
biotin-carboxyl carrier protein assembly,
purine nucleotide metabolism (phosphotransfer and nucleotide modification),
UDP-D-galacturonate biosynthesis II (from D-galacturonate),
asparagine biosynthesis III (tRNA-dependent),
superpathway of glyoxylate cycle and fatty acid degradation,
NAD/NADH phosphorylation and dephosphorylation,
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3),
galactose degradation I (Leloir pathway),
uridine-5'-phosphate biosynthesis,
lipid-dependent phytate biosynthesis II (via Ins(1,3,4)P3),
sucrose degradation III,
lysine biosynthesis VI,
sphingolipid biosynthesis (plants),
choline biosynthesis I,
GDP-glucose biosynthesis,
photorespiration,
gamma-glutamyl cycle (plant pathway),
5-aminoimidazole ribonucleotide biosynthesis I,
gamma-glutamyl cycle,
thiamine biosynthesis II,
proline biosynthesis III,
glutathione biosynthesis,
folate transformations II,
ornithine biosynthesis,
diphthamide biosynthesis,
S-methyl-5'-thioadenosine degradation I,
starch biosynthesis,
arginine biosynthesis I,
homoserine biosynthesis,
flavin biosynthesis I (bacteria and plants),
sucrose biosynthesis I,
leucine degradation I,
glycolysis I,
pyrimidine ribonucleotides interconversion,
1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza),
glycolysis IV (plant cytosol),
Calvin-Benson-Bassham cycle,
UDP-D-glucuronate biosynthesis (from myo-inositol),
guanine and guanosine salvage III,
glutamine biosynthesis III,
L-glutamine biosynthesis II (tRNA-dependent),
GDP-L-fucose biosynthesis II (from L-fucose),
nitrate reduction II (assimilatory),
ammonia assimilation cycle II,
gluconeogenesis I,
threonine biosynthesis from homoserine,
mannose degradation,
urea cycle,
lipid-dependent phytate biosynthesis I (via Ins(1,4,5)P3),
biotin biosynthesis II 		0.65 0.45 -0.42 C0053
58 C0095 Galacturonic acid D-Galacturonic acid D-Galacturonate UDP-D-galacturonate biosynthesis II (from D-galacturonate) 0.64 0.31 -0.31 C0095
59 C0075 dGDP - dGDP purine nucleotide metabolism (phosphotransfer and nucleotide modification) 0.64 0.42 -0.44 C0075
60 C0073 Cysteine L-Cysteine L-Cysteine alanine biosynthesis III,
cysteine biosynthesis I,
gamma-glutamyl cycle (plant pathway),
farnesylcysteine salvage pathway,
molybdenum cofactor biosynthesis,
thiamine biosynthesis II,
cyanide detoxification II,
indole glucosinolate breakdown (insect chewing induced),
glutathione degradation,
glutathione biosynthesis,
molybdenum cofactor biosynthesis II (eukaryotes),
cyanide degradation,
homocysteine and cysteine interconversion,
methionine biosynthesis II,
tRNA charging,
gamma-glutamyl cycle,
coenzyme A biosynthesis 		0.63 0.44 -0.43 C0073
61 C0142 Malonic acid - Malonate fatty acid biosynthesis (plant mitochondria) 0.6 0.32 -0.3 C0142
62 C0218 Pyridoxamine phosphate Pyridoxamine-5'-phosphate Pyridoxamine-5'-phosphate pyridoxal 5'-phosphate salvage pathway 0.59 0.3 -0.34 C0218